The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation NG Seidah, S Benjannet, L Wickham, J Marcinkiewicz, SB Jasmin, ... Proceedings of the National Academy of Sciences 100 (3), 928-933, 2003 | 1475 | 2003 |
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides NG Seidah, M Chrétien Brain research 848 (1-2), 45-62, 1999 | 940 | 1999 |
NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol S Benjannet, D Rhainds, R Essalmani, J Mayne, L Wickham, W Jin, ... Journal of Biological Chemistry 279 (47), 48865-48875, 2004 | 795 | 2004 |
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. S Benjannet, N Rondeau, R Day, M Chretien, NG Seidah Proceedings of the National Academy of Sciences 88 (9), 3564-3568, 1991 | 788 | 1991 |
PCSK9: a key modulator of cardiovascular health NG Seidah, Z Awan, M Chrétien, M Mbikay Circulation research 114 (6), 1022-1036, 2014 | 656 | 2014 |
cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases NG Seidah, L Gaspar, P Mion, M Marcinkiewicz, M Mbikay, M Chretien DNA and cell biology 9 (6), 415-424, 1990 | 592 | 1990 |
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution … NG Seidah, M Marcinkiewicz, S Benjannet, L Gaspar, G Beaubien, ... Molecular Endocrinology 5 (1), 111-122, 1991 | 557 | 1991 |
The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions NG Seidah, M Chretien, R Day Biochimie 76 (3-4), 197-209, 1994 | 504 | 1994 |
Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases NG Seidah, S Benjannet, S Pareek, M Chrétien, RA Murphy FEBS letters 379 (3), 247-250, 1996 | 474 | 1996 |
Amino acids of the Torpedo marmorata acetylcholine receptor. alpha. subunit labeled by a photoaffinity ligand for the acetylcholine binding site M Dennis, J Giraudat, F Kotzyba-Hibert, M Goeldner, C Hirth, JY Chang, ... Biochemistry 27 (7), 2346-2357, 1988 | 415 | 1988 |
Post-translational processing of β-secretase (β-amyloid-converting enzyme) and its ectodomain shedding: the pro-and transmembrane/cytosolic domains affect its cellular activity … S Benjannet, A Elagoz, L Wickham, M Mamarbachi, JS Munzer, A Basak, ... Journal of Biological Chemistry 276 (14), 10879-10887, 2001 | 409 | 2001 |
Mammalian subtilisin/kexin isozyme SKI-1: a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization NG Seidah, SJ Mowla, J Hamelin, AM Mamarbachi, S Benjannet, ... Proceedings of the National Academy of Sciences 96 (4), 1321-1326, 1999 | 397 | 1999 |
Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases NG Seidah, S Benjannet, S Pareek, D Savaria, J Hamelin, B Goulet, ... Biochemical Journal 314 (3), 951-960, 1996 | 379 | 1996 |
Isolation and amino-acid sequence of β-LPH from sheep pituitary glands C Hao Li, L Barnafi, M Chrétien, D Chung Nature 208 (5015), 1093-1094, 1965 | 352 | 1965 |
Eukaryotic protein processing: endoproteolysis of precursor proteins NG Seidah, M Chrétien Current opinion in biotechnology 8 (5), 602-607, 1997 | 346 | 1997 |
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis G Siegfried, A Basak, JA Cromlish, S Benjannet, J Marcinkiewicz, ... The Journal of clinical investigation 111 (11), 1723-1732, 2003 | 320 | 2003 |
Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary. R Day, MK Schafer, SJ Watson, M Chretien, NG Seidah Molecular Endocrinology 6 (3), 485-497, 1992 | 317 | 1992 |
cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells. J Lusson, D Vieau, J Hamelin, R Day, M Chretien, NG Seidah Proceedings of the National Academy of Sciences 90 (14), 6691-6695, 1993 | 314 | 1993 |
cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. NG Seidah, J Hamelin, M Mamarbachi, W Dong, H Tardos, M Mbikay, ... Proceedings of the National Academy of Sciences 93 (8), 3388-3393, 1996 | 307 | 1996 |
Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms. NG Seidah, C Lazure, M Chretien, G Thibault, R Garcia, M Cantin, ... Proceedings of the National Academy of Sciences 81 (9), 2640-2644, 1984 | 301 | 1984 |