Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice LA Hancock, CE Hennessy, GM Solomon, E Dobrinskikh, A Estrella, ... Nature communications 9 (1), 5363, 2018 | 198 | 2018 |
Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis CR Esther, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ... Science translational medicine 11 (486), eaav3488, 2019 | 184 | 2019 |
Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH DB Hill, RF Long, WJ Kissner, E Atieh, IC Garbarine, MR Markovetz, ... European Respiratory Journal 52 (6), 2018 | 123 | 2018 |
Mucus, mucins, and cystic fibrosis CB Morrison, MR Markovetz, C Ehre Pediatric pulmonology 54, S84-S96, 2019 | 114 | 2019 |
An improved inhaled mucolytic to treat airway muco-obstructive diseases C Ehre, ZL Rushton, B Wang, LN Hothem, CB Morrison, NC Fontana, ... American journal of respiratory and critical care medicine 199 (2), 171-180, 2019 | 98 | 2019 |
Endotracheal tube mucus as a source of airway mucus for rheological study MR Markovetz, DB Subramani, WJ Kissner, CB Morrison, IC Garbarine, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (4 …, 2019 | 47 | 2019 |
Treatment of cystic fibrosis airway cells with CFTR modulators reverses aberrant mucus properties via hydration CB Morrison, KM Shaffer, KC Araba, MR Markovetz, JA Wykoff, ... European Respiratory Journal 59 (2), 2022 | 46 | 2022 |
Pseudomonas infection and mucociliary and absorptive clearance in the cystic fibrosis lung LW Locke, MM Myerburg, DJ Weiner, MR Markovetz, RS Parker, ... European Respiratory Journal 47 (5), 1392-1401, 2016 | 29 | 2016 |
Quantitative imaging of airway liquid absorption in cystic fibrosis LW Locke, MM Myerburg, MR Markovetz, RS Parker, L Weber, ... European Respiratory Journal 44 (3), 675-684, 2014 | 26 | 2014 |
Pseudomonas aeruginosa Biofilm Eradication via Nitric Oxide-Releasing Cyclodextrins KR Rouillard, MR Markovetz, LG Bacudio, DB Hill, MH Schoenfisch ACS Infectious Diseases 6 (7), 1940-1950, 2020 | 23 | 2020 |
Induction of ciliary orientation by matrix patterning and characterization of mucociliary transport PR Sears, XM Bustamante-Marin, H Gong, MR Markovetz, R Superfine, ... Biophysical Journal 120 (8), 1387-1395, 2021 | 20 | 2021 |
Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis MR Markovetz, IC Garbarine, CB Morrison, WJ Kissner, I Seim, MG Forest, ... Journal of Cystic Fibrosis 21 (6), 959-966, 2022 | 16 | 2022 |
Effects of mucin and DNA concentrations in airway mucus on Pseudomonas aeruginosa biofilm recalcitrance KR Rouillard, WJ Kissner, MR Markovetz, DB Hill Msphere 7 (4), e00291-22, 2022 | 16 | 2022 |
Overnight delivery of hypertonic saline by nasal cannula aerosol for cystic fibrosis TE Corcoran, JE Godovchik, KH Donn, DR Busick, J Goralski, LW Locke, ... Pediatric pulmonology 52 (9), 1142-1149, 2017 | 15 | 2017 |
A physiologically-motivated compartment-based model of the effect of inhaled hypertonic saline on mucociliary clearance and liquid transport in cystic fibrosis MR Markovetz, TE Corcoran, LW Locke, MM Myerburg, JM Pilewski, ... PloS one 9 (11), e111972, 2014 | 14 | 2014 |
Biochemical and rheological analysis of human colonic culture mucus reveals similarity to gut mucus RL Howard, M Markovetz, Y Wang, C Ehre, SZ Sheikh, NL Allbritton, ... Biophysical Journal 120 (23), 5384-5394, 2021 | 13 | 2021 |
Molecular dynamics simulations to explore the structure and rheological properties of normal and hyperconcentrated airway mucus AG Ford, XZ Cao, MJ Papanikolas, T Kato, RC Boucher, MR Markovetz, ... Studies in Applied Mathematics 147 (4), 1369-1387, 2021 | 13 | 2021 |
Mucus concentration–dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis T Kato, G Radicioni, MJ Papanikolas, GV Stoychev, MR Markovetz, K Aoki, ... Science Advances 8 (13), eabm9718, 2022 | 10 | 2022 |
Altering the viscoelastic properties of mucus-grown Pseudomonas aeruginosa biofilms affects antibiotic susceptibility KR Rouillard, MR Markovetz, WJ Kissner, WL Boone, LM Plott, DB Hill Biofilm 5, 100104, 2023 | 7 | 2023 |
Delivery characterization of SPL84 inhaled antisense oligonucleotide drug for 3849+ 10 kb C-> T cystic fibrosis patients E Ozeri-Galai, L Friedman, O Barchad-Avitzur, MR Markovetz, W Boone, ... nucleic acid therapeutics 33 (5), 306-318, 2023 | 5 | 2023 |