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Mahan Gholam Azad
Mahan Gholam Azad
Griffith Institute of Drug Discovery
在 griffith.edu.au 的电子邮件经过验证
标题
引用次数
引用次数
年份
Parkinson's disease: alterations in iron and redox biology as a key to unlock therapeutic strategies
L Ma, MG Azad, M Dharmasivam, V Richardson, RJ Quinn, Y Feng, ...
Redox biology 41, 101896, 2021
872021
The oncogenic signaling disruptor, NDRG1: molecular and cellular mechanisms of activity
J Chekmarev, MG Azad, DR Richardson
Cells 10 (9), 2382, 2021
412021
Designing tailored thiosemicarbazones with bespoke properties: The styrene moiety imparts potent activity, inhibits heme center oxidation, and results in a novel “Stealth Zinc …
M Dharmasivam, B Kaya, T Wijesinghe, M Gholam Azad, MA Gonzalvez, ...
Journal of Medicinal Chemistry 66 (2), 1426-1453, 2023
152023
The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature-and energy-dependent uptake by tumor cells
M Dharmasivam, MG Azad, R Afroz, V Richardson, PJ Jansson, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1866 (8), 130152, 2022
152022
Ascorbate-and iron-driven redox activity of Dp44mT and Emodin facilitates peroxidation of micelles and bicelles
OY Selyutina, PA Kononova, VE Koshman, EA Shelepova, MG Azad, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1866 (4), 130078, 2022
112022
Calcium channels and iron metabolism: A redox catastrophe in Parkinson's disease and an innovative path to novel therapies?
MK Boag, L Ma, GD Mellick, DL Pountney, Y Feng, RJ Quinn, AWC Liew, ...
Redox Biology 47, 102136, 2021
72021
The Relationship of Glutathione-S-Transferase and Multi-Drug Resistance-Related Protein 1 in Nitric Oxide (NO) Transport and Storage
TM Russell, MG Azad, DR Richardson
Molecules 26 (19), 5784, 2021
72021
Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen-and prolactin-receptors in breast cancer
F Shehadeh-Tout, HH Milioli, S Roslan, PJ Jansson, M Dharmasivam, ...
Pharmacological Research 193, 106806, 2023
52023
Parkinson’s disease: alterations in iron and redox biology as a key to unlock therapeutic strategies. Redox Biol 41: 101896
L Ma, M Gholam Azad, M Dharmasivam, V Richardson, RJ Quinn, Y Feng, ...
52021
Ascorbate and tumor cell iron metabolism: The evolving story and its link to pathology
DH Bae, M Gholam Azad, DS Kalinowski, DJR Lane, PJ Jansson, ...
Antioxidants & Redox Signaling 33 (12), 816-838, 2020
52020
Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure–Activity Relationships of the Novel PPP4pT Series
TP Wijesinghe, B Kaya, MA Gonzálvez, JR Harmer, M Gholam Azad, ...
Journal of Medicinal Chemistry 66 (22), 15453-15476, 2023
42023
Differential transmetallation of complexes of the anti-cancer thiosemicarbazone, Dp4e4mT: effects on anti-proliferative efficacy, redox activity, oxy-myoglobin and oxy …
M Dharmasivam, B Kaya, TP Wijesinghe, V Richardson, JR Harmer, ...
Chemical Science 15 (3), 974-990, 2024
32024
An innovative non-hormonal strategy targeting redox active metals to down-regulate estrogen-, progesterone-, androgen-and prolactin-receptors in breast cancer
F Shehadeh-Tout, HH Milioli, S Roslan, PJ Jansson, M Dharmasivam, ...
bioRxiv, 2023.02. 02.526543, 2023
32023
Thiosemicarbazones reprogram pancreatic cancer bidirectional oncogenic signaling between cancer cells and stellate cells to suppress desmoplasia
DR Richardson, MG Azad, R Afroz, V Richardson, M Dharmasivam
Future Medicinal Chemistry 14 (13), 1005-1017, 2022
22022
Melanotransferrin Functions as a Pro-Oncogenic WNT Agonist: A Yin-Yang Relationship in Melanoma with the WNT Antagonist and Metastasis Suppressor, NDRG1
J Paluncic, M Gholam Azad, DJR Lane, J Skoda, KC Park, S Chiang, ...
bioRxiv, 2023.02. 27.530353, 2023
12023
Isosteric Replacement of Sulfur to Selenium in a Thiosemicarbazone: Promotion of Zn (II) Complex Dissociation and Transmetalation to Augment Anticancer Efficacy
B Kaya, M Gholam Azad, M Suleymanoglu, JR Harmer, TP Wijesinghe, ...
Journal of Medicinal Chemistry, 2024
2024
Multi-modal mechanisms of the metastasis suppressor, NDRG1: Inhibition of WNT/β-catenin signaling by stabilization of protein kinase Cα
MG Azad, M Hussaini, TM Russell, V Richardson, B Kaya, ...
Journal of Biological Chemistry, 107417, 2024
2024
Correction to “Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure–Activity Relationships of the Novel PPP4pT Series’’
TP Wijesinghe, B Kaya, MA Gonzálvez, JR Harmer, M Gholam Azad, ...
Journal of Medicinal Chemistry 67 (8), 6893-6893, 2024
2024
Steric Blockade of Oxy-Myoglobin Oxidation by Thiosemicarbazones: Structure-Activity Relationships of the Novel PPP4pT Series (Vol 66, pg 15453, 2023)
TP Wijesinghe, B Kaya, MA Gonzalvez, JR Harmer, M Gholam Azad, ...
JOURNAL OF MEDICINAL CHEMISTRY, 2024
2024
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