Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease EM Kennedy, AVR Kornepati, M Goldstein, HP Bogerd, BC Poling, ... Journal of virology 88 (20), 11965-11972, 2014 | 334 | 2014 |
In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms AW Whisnant, HP Bogerd, O Flores, P Ho, JG Powers, N Sharova, ... MBio 4 (2), 10.1128/mbio. 00193-13, 2013 | 159 | 2013 |
Replication of many human viruses is refractory to inhibition by endogenous cellular microRNAs HP Bogerd, RL Skalsky, EM Kennedy, Y Furuse, AW Whisnant, O Flores, ... Journal of virology 88 (14), 8065-8076, 2014 | 155 | 2014 |
Derivation and characterization of Dicer-and microRNA-deficient human cells HP Bogerd, AW Whisnant, EM Kennedy, O Flores, BR Cullen Rna 20 (6), 923-937, 2014 | 123 | 2014 |
Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture O Flores, S Nakayama, AW Whisnant, H Javanbakht, BR Cullen, ... Journal of virology 87 (12), 6589-6603, 2013 | 116 | 2013 |
Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer EM Kennedy, AW Whisnant, AVR Kornepati, JB Marshall, HP Bogerd, ... Proceedings of the National Academy of Sciences 112 (50), E6945-E6954, 2015 | 89 | 2015 |
Integrative functional genomics decodes herpes simplex virus 1 AW Whisnant, CS Jürges, T Hennig, E Wyler, B Prusty, AJ Rutkowski, ... Nature communications 11 (1), 2038, 2020 | 88 | 2020 |
HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes T Hennig, M Michalski, AJ Rutkowski, L Djakovic, AW Whisnant, MS Friedl, ... PLoS pathogens 14 (3), e1006954, 2018 | 84 | 2018 |
Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27 X Wang, T Hennig, AW Whisnant, F Erhard, BK Prusty, CC Friedel, ... Nature communications 11 (1), 293, 2020 | 74 | 2020 |
Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus AW Whisnant, T Kehl, Q Bao, M Materniak, J Kuzmak, M Löchelt, ... Journal of Virology 88 (9), 4679-4686, 2014 | 66 | 2014 |
Dissecting herpes simplex virus 1-induced host shutoff at the RNA level CC Friedel, AW Whisnant, L Djakovic, AJ Rutkowski, MS Friedl, M Kluge, ... Journal of Virology 95 (3), 10.1128/jvi. 01399-20, 2021 | 37 | 2021 |
Selective inhibition of miRNA processing by a herpesvirus-encoded miRNA T Hennig, AB Prusty, BB Kaufer, AW Whisnant, M Lodha, A Enders, ... Nature 605 (7910), 539-544, 2022 | 29 | 2022 |
Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation X Wang, L Liu, AW Whisnant, T Hennig, L Djakovic, N Haque, C Bach, ... PLoS genetics 17 (3), e1009263, 2021 | 20 | 2021 |
Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27. Nat Commun 11: 293 X Wang, T Hennig, AW Whisnant, F Erhard, BK Prusty, CC Friedel, ... | 15 | 2020 |
Induced packaging of cellular microRNAs into HIV-1 virions can inhibit infectivity HP Bogerd, EM Kennedy, AW Whisnant, BR Cullen MBio 8 (1), 10.1128/mbio. 02125-16, 2017 | 15 | 2017 |
A review of the multipronged attack of herpes simplex virus 1 on the host transcriptional machinery T Hennig, L Djakovic, L Dölken, AW Whisnant Viruses 13 (9), 1836, 2021 | 10 | 2021 |
HSV-1 infection induces a downstream shift of promoter-proximal pausing for host genes E Weiß, T Hennig, P Graßl, L Djakovic, AW Whisnant, CS Jürges, F Koller, ... Journal of Virology 97 (5), e00381-23, 2023 | 5 | 2023 |
Concatemeric Broccoli reduces mRNA stability and induces aggregates MR Rink, MAP Baptista, FJ Flomm, T Hennig, AW Whisnant, N Wolf, ... Plos one 16 (8), e0244166, 2021 | 5 | 2021 |
The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes L Djakovic, T Hennig, K Reinisch, A Milić, AW Whisnant, K Wolf, E Weiß, ... Nature Communications 14 (1), 4591, 2023 | 4 | 2023 |
HSV-1 and influenza infection induce linear and circular splicing of the long NEAT1 isoform MS Friedl, L Djakovic, M Kluge, T Hennig, AW Whisnant, S Backes, ... Plos one 17 (10), e0276467, 2022 | 2 | 2022 |