| GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation M Shigeto, R Ramracheya, AI Tarasov, CY Cha, MV Chibalina, B Hastoy, ... The Journal of clinical investigation 125 (12), 4714-4728, 2015 | 175 | 2015 |
| Engineering a model cell for rational tuning of GPCR signaling WM Shaw, H Yamauchi, J Mead, GOF Gowers, DJ Bell, D Öling, ... Cell 177 (3), 782-796. e27, 2019 | 171 | 2019 |
| Ras activation revisited: role of GEF and GAP systems A Hennig, R Markwart, MA Esparza-Franco, G Ladds, I Rubio Biological chemistry 396 (8), 831-848, 2015 | 127 | 2015 |
| Functional analysis of heterologous GPCR signalling pathways in yeast G Ladds, A Goddard, J Davey Trends in biotechnology 23 (7), 367-373, 2005 | 121 | 2005 |
| Combinatorial expression of GPCR isoforms affects signalling and drug responses M Marti-Solano, SE Crilly, D Malinverni, C Munk, M Harris, A Pearce, ... Nature 587 (7835), 650-656, 2020 | 96 | 2020 |
| Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors C Weston, I Winfield, M Harris, R Hodgson, A Shah, SJ Dowell, ... Journal of Biological Chemistry 291 (42), 21925-21944, 2016 | 94 | 2016 |
| Corticotropin-releasing hormone receptors EW Hillhouse, H Randeva, G Ladds, D Grammatopoulos Biochemical Society Transactions 30 (4), 428-432, 2002 | 80 | 2002 |
| Modulation of glucagon receptor pharmacology by receptor activity-modifying protein-2 (RAMP2) C Weston, J Lu, N Li, K Barkan, GO Richards, DJ Roberts, TM Skerry, ... Journal of Biological Chemistry 290 (38), 23009-23022, 2015 | 75 | 2015 |
| Paracrine oxytocin and estradiol demonstrate a spatial increase in human intrauterine tissues with labor AM Blanks, M Vatish, MJ Allen, G Ladds, NCJ de Wit, DM Slater, ... The Journal of Clinical Endocrinology & Metabolism 88 (7), 3392-3400, 2003 | 75 | 2003 |
| BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, ... Nature communications 9 (1), 3327, 2018 | 64 | 2018 |
| Modified yeast cells to investigate the coupling of G protein‐coupled receptors to specific G proteins G Ladds, K Davis, EW Hillhouse, J Davey Molecular Microbiology 47 (3), 781-792, 2003 | 64 | 2003 |
| Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulum S Li, RA Spooner, SCH Allen, CP Guise, G Ladds, T Schnöder, ... Molecular biology of the cell 21 (15), 2543-2554, 2010 | 60 | 2010 |
| Investigating G protein signalling bias at the glucagon‐like peptide‐1 receptor in yeast C Weston, D Poyner, V Patel, S Dowell, G Ladds British journal of pharmacology 171 (15), 3651-3665, 2014 | 59 | 2014 |
| The sxa2‐dependent inactivation of the P‐factor mating pheromone in the fission yeast Schizosaccharomyces pombe G Ladds, EM Rasmussen, T Young, O Nielsen, J Davey Molecular microbiology 20 (1), 35-42, 1996 | 52 | 1996 |
| Discovery of novel adenosine receptor agonists that exhibit subtype selectivity A Knight, JL Hemmings, I Winfield, M Leuenberger, E Frattini, ... Journal of medicinal chemistry 59 (3), 947-964, 2016 | 47 | 2016 |
| A constitutively active GPCR retains its G protein specificity and the ability to form dimers G Ladds, K Davis, A Das, J Davey Molecular microbiology 55 (2), 482-497, 2005 | 46 | 2005 |
| RAMP3 determines rapid recycling of atypical chemokine receptor-3 for guided angiogenesis DI Mackie, NR Nielsen, M Harris, S Singh, RB Davis, D Dy, G Ladds, ... Proceedings of the National Academy of Sciences 116 (48), 24093-24099, 2019 | 44 | 2019 |
| Feedback activation of neurofibromin terminates growth factor-induced Ras activation A Hennig, R Markwart, K Wolff, K Schubert, Y Cui, IA Prior, ... Cell Communication and Signaling 14, 1-14, 2016 | 41 | 2016 |
| Receptor activity-modifying proteins; multifunctional G protein-coupled receptor accessory proteins DL Hay, CS Walker, JJ Gingell, G Ladds, CA Reynolds, DR Poyner Biochemical Society Transactions 44 (2), 568-573, 2016 | 41 | 2016 |
| Differential effects of RGS proteins on Gαq and Gα11 activity G Ladds, A Goddard, C Hill, S Thornton, J Davey Cellular signalling 19 (1), 103-113, 2007 | 40 | 2007 |
