| Structure− function relationships in aminoquinolines: effect of amino and chloro groups on quinoline− hematin complex formation, inhibition of β-hematin formation, and … TJ Egan, R Hunter, CH Kaschula, HM Marques, A Misplon, J Walden Journal of medicinal chemistry 43 (2), 283-291, 2000 | 428 | 2000 |
| Health benefits of resveratrol: Evidence from clinical studies AP Singh, R Singh, SS Verma, V Rai, CH Kaschula, P Maiti, SC Gupta Medicinal research reviews 39 (5), 1851-1891, 2019 | 398 | 2019 |
| Structure− activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position CH Kaschula, TJ Egan, R Hunter, N Basilico, S Parapini, D Taramelli, ... Journal of Medicinal Chemistry 45 (16), 3531-3539, 2002 | 313 | 2002 |
| The immunomodulation and anti-inflammatory effects of garlic organosulfur compounds in cancer chemoprevention G Schafer, C H Kaschula Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2014 | 239 | 2014 |
| Speciation and structure of ferriprotoporphyrin IX in aqueous solution: spectroscopic and diffusion measurements demonstrate dimerization, but not μ-oxo dimer formation KA de Villiers, CH Kaschula, TJ Egan, HM Marques JBIC Journal of Biological Inorganic Chemistry 12, 101-117, 2007 | 183 | 2007 |
| Garlic‐derived anticancer agents: Structure and biological activity of ajoene CH Kaschula, R Hunter, MI Parker Biofactors 36 (1), 78-85, 2010 | 100 | 2010 |
| Strategies to reverse drug resistance in malaria TJ Egan, CH Kaschula Current opinion in infectious diseases 20 (6), 598-604, 2007 | 89 | 2007 |
| Structure–activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells CH Kaschula, R Hunter, N Stellenboom, MR Caira, S Winks, T Ogunleye, ... European journal of medicinal chemistry 50, 236-254, 2012 | 77 | 2012 |
| Forkhead box Q1 is a novel target of breast cancer stem cell inhibition by diallyl trisulfide SH Kim, CH Kaschula, N Priedigkeit, AV Lee, SV Singh Journal of Biological Chemistry 291 (26), 13495-13508, 2016 | 70 | 2016 |
| A phenolate-induced trans influence: Crystallographic evidence for unusual asymmetric coordination of an α-diimine in ternary complexes of iron (III) possessing biologically … MS Shongwe, CH Kaschula, MS Adsetts, EW Ainscough, AM Brodie, ... Inorganic chemistry 44 (9), 3070-3079, 2005 | 64 | 2005 |
| Substituted ajoenes as novel anti-cancer agents R Hunter, CH Kaschula, IM Parker, MR Caira, P Richards, S Travis, ... Bioorganic & medicinal chemistry letters 18 (19), 5277-5279, 2008 | 61 | 2008 |
| The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells CH Kaschula, R Tuveri, E Ngarande, K Dzobo, C Barnett, DA Kusza, ... BMC cancer 19, 1-16, 2019 | 53 | 2019 |
| The garlic compound ajoene targets protein folding in the endoplasmic reticulum of cancer cells CH Kaschula, R Hunter, J Cotton, R Tuveri, E Ngarande, K Dzobo, ... Molecular carcinogenesis 55 (8), 1213-1228, 2016 | 48 | 2016 |
| Anti-proliferative activity of synthetic ajoene analogues on cancer cell-lines C H Kaschula, R Hunter, H T Hassan, N Stellenboom, J Cotton, X Q Zhai, ... Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2011 | 46 | 2011 |
| The cytotoxicity of garlic-related disulphides and thiosulfonates in WHCO1 oesophageal cancer cells is dependent on S-thiolation and not production of ROS M Smith, R Hunter, N Stellenboom, DA Kusza, MI Parker, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (7), 1439-1449, 2016 | 44 | 2016 |
| The cytotoxicity of the ajoene analogue BisPMB in WHCO1 oesophageal cancer cells is mediated by CHOP/GADD153 V Siyo, G Schäfer, R Hunter, A Grafov, I Grafova, M Nieger, AA Katz, ... Molecules 22 (6), 892, 2017 | 35 | 2017 |
| Synthesis and anti-prion activity evaluation of aminoquinoline analogues B Macedo, CH Kaschula, R Hunter, JAP Chaves, JD van der Merwe, ... European journal of medicinal chemistry 45 (11), 5468-5473, 2010 | 26 | 2010 |
| Transition metal-alkenyl complexes [M–(CH2) nCHCH2, n≥ 2]: Synthesis, structure, reactivity and applications A Sivaramakrishna, HS Clayton, C Kaschula, JR Moss Coordination chemistry reviews 251 (9-10), 1294-1308, 2007 | 25 | 2007 |
| Acyl CoA: retinol acyltransferase (ARAT) activity is present in bovine retinal pigment epithelium CH Kaschula, M Jin, NS Desmond-Smith, GH Travis Experimental eye research 82 (1), 111-121, 2006 | 25 | 2006 |
| Synthesis and structure–activity relations in allylsulfide and isothiocyanate compounds from garlic and broccoli against in vitro cancer cell growth CH Kaschula, R Hunter Studies in Natural Products Chemistry 50, 1-43, 2016 | 16 | 2016 |
