| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 11212 | 2021 |
| Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants JC Greene, AJ Whitworth, I Kuo, LA Andrews, MB Feany, LJ Pallanck Proceedings of the National Academy of Sciences 100 (7), 4078-4083, 2003 | 1430 | 2003 |
| The PINK1/Parkin pathway regulates mitochondrial morphology AC Poole, RE Thomas, LA Andrews, HM McBride, AJ Whitworth, ... Proceedings of the National Academy of Sciences 105 (5), 1638-1643, 2008 | 1036 | 2008 |
| Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin E Ziviani, RN Tao, AJ Whitworth Proceedings of the National Academy of Sciences 107 (11), 5018-5023, 2010 | 843 | 2010 |
| PINK1 cleavage at position A103 by the mitochondrial protease PARL E Deas, H Plun-Favreau, S Gandhi, H Desmond, S Kjaer, SHY Loh, ... Human molecular genetics 20 (5), 867-879, 2011 | 564 | 2011 |
| Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease AJ Whitworth, DA Theodore, JC Greene, H Beneš, PD Wes, LJ Pallanck Proceedings of the National Academy of Sciences 102 (22), 8024-8029, 2005 | 482 | 2005 |
| The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy CP Webster, EF Smith, CS Bauer, A Moller, GM Hautbergue, L Ferraiuolo, ... The EMBO journal 35 (15), 1656-1676, 2016 | 473 | 2016 |
| Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson’s disease M Meulener, AJ Whitworth, CE Armstrong-Gold, P Rizzu, P Heutink, ... Current Biology 15 (17), 1572-1577, 2005 | 421 | 2005 |
| The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy VS Burchell, DE Nelson, A Sanchez-Martinez, M Delgado-Camprubi, ... Nature neuroscience 16 (9), 1257-1265, 2013 | 370 | 2013 |
| Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss LS Tain, H Mortiboys, RN Tao, E Ziviani, O Bandmann, AJ Whitworth Nature neuroscience 12 (9), 1129-1135, 2009 | 368 | 2009 |
| The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinson’s disease DC Schöndorf, D Ivanyuk, P Baden, A Sanchez-Martinez, S De Cicco, ... Cell reports 23 (10), 2976-2988, 2018 | 337 | 2018 |
| Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin JJ Lee, A Sanchez-Martinez, AM Zarate, C Benincá, U Mayor, MJ Clague, ... Journal of Cell Biology 217 (5), 1613-1622, 2018 | 308 | 2018 |
| Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations VK Godena, N Brookes-Hocking, A Moller, G Shaw, M Oswald, ... Nature communications 5 (1), 5245, 2014 | 298 | 2014 |
| Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis JC Greene, AJ Whitworth, LA Andrews, TJ Parker, LJ Pallanck Human molecular genetics 14 (6), 799-811, 2005 | 235 | 2005 |
| Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson’s disease factors Pink1 and Parkin AJ Whitworth, JR Lee, VMW Ho, R Flick, R Chowdhury, GA McQuibban Disease models & mechanisms 1 (2-3), 168-174, 2008 | 228 | 2008 |
| Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models A Sanchez-Martinez, M Beavan, ME Gegg, KY Chau, AJ Whitworth, ... Scientific reports 6 (1), 31380, 2016 | 173 | 2016 |
| PINK1/Parkin mitophagy and neurodegeneration—what do we really know in vivo? AJ Whitworth, LJ Pallanck Current opinion in genetics & development 44, 47-53, 2017 | 170 | 2017 |
| The PINK1/Parkin pathway: a mitochondrial quality control system? AJ Whitworth, LJ Pallanck Journal of bioenergetics and biomembranes 41, 499-503, 2009 | 160 | 2009 |
| Drosophila models pioneer a new approach to drug discovery for Parkinson's disease AJ Whitworth, PD Wes, LJ Pallanck Drug discovery today 11 (3-4), 119-126, 2006 | 154 | 2006 |
| SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ... Nature communications 8 (1), 16063, 2017 | 149 | 2017 |
