| Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state M Foretz, S Hébrard, J Leclerc, E Zarrinpashneh, M Soty, G Mithieux, ... The Journal of clinical investigation 120 (7), 2355-2369, 2010 | 1446 | 2010 |
| LKB1-dependent signaling pathways DR Alessi, K Sakamoto, JR Bayascas Annu. Rev. Biochem. 75, 137-163, 2006 | 905 | 2006 |
| The ancient drug salicylate directly activates AMP-activated protein kinase SA Hawley, MD Fullerton, FA Ross, JD Schertzer, C Chevtzoff, KJ Walker, ... Science 336 (6083), 918-922, 2012 | 820 | 2012 |
| Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis EJ McManus, K Sakamoto, LJ Armit, L Ronaldson, N Shpiro, R Marquez, ... The EMBO journal 24 (8), 1571-1583, 2005 | 736 | 2005 |
| AMPK: a key sensor of fuel and energy status in skeletal muscle DG Hardie, K Sakamoto Physiology 21 (1), 48-60, 2006 | 732 | 2006 |
| Anti-inflammatory effects of metformin irrespective of diabetes status AR Cameron, VL Morrison, D Levin, M Mohan, C Forteath, C Beall, ... Circulation research 119 (5), 652-665, 2016 | 669 | 2016 |
| Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction K Sakamoto, A McCarthy, D Smith, KA Green, D Grahame Hardie, ... The EMBO journal 24 (10), 1810-1820, 2005 | 661 | 2005 |
| Molecular mechanism of action of metformin: old or new insights? G Rena, ER Pearson, K Sakamoto Diabetologia 56, 1898-1906, 2013 | 633 | 2013 |
| Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic K Sakamoto, GD Holman American journal of physiology-endocrinology and metabolism 295 (1), E29-E37, 2008 | 610 | 2008 |
| Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase O Göransson, A McBride, SA Hawley, FA Ross, N Shpiro, M Foretz, ... Journal of Biological Chemistry 282 (45), 32549-32560, 2007 | 505 | 2007 |
| Important role of the LKB1-AMPK pathway in suppressing tumourigenesis in PTEN deficient mice X Huang, S Wullschleger, N Shpiro, VA McGuire, K Sakamoto, YL Woods, ... Biochemical Journal 412 (2), 211-221, 2010 | 483 | 2010 |
| How long does the protective effect on eccentric exercise-induced muscle damage last? K Nosaka, KEI Sakamoto, M Newton, P Sacco Medicine & Science in Sports & Exercise 33 (9), 1490-1495, 2001 | 458 | 2001 |
| AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration R Mounier, M Théret, L Arnold, S Cuvellier, L Bultot, O Göransson, N Sanz, ... Cell metabolism 18 (2), 251-264, 2013 | 456 | 2013 |
| Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells FVN Din, A Valanciute, V Houde, D Zibrova, KA Green, K Sakamoto, ... Gastroenterology, 2012 | 447 | 2012 |
| Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study A Sriwijitkamol, DK Coletta, E Wajcberg, GB Balbontin, SM Reyna, ... Diabetes 56 (3), 836-848, 2007 | 429 | 2007 |
| Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle HF Kramer, CA Witczak, N Fujii, N Jessen, EB Taylor, DE Arnolds, ... Diabetes 55 (7), 2067-2076, 2006 | 412 | 2006 |
| Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR K Sakamoto, O Goransson, DG Hardie, DR Alessi American Journal of Physiology-Endocrinology and Metabolism 287 (2), E310-E317, 2004 | 399 | 2004 |
| Invited review: intracellular signaling in contracting skeletal muscle K Sakamoto, LJ Goodyear Journal of applied physiology 93 (1), 369-383, 2002 | 356 | 2002 |
| Reduced expression of the murine p85α subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes F Mauvais-Jarvis, K Ueki, DA Fruman, MF Hirshman, K Sakamoto, ... The Journal of clinical investigation 109 (1), 141-149, 2002 | 352 | 2002 |
| Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function EP Mottillo, EM Desjardins, JD Crane, BK Smith, AE Green, S Ducommun, ... Cell metabolism 24 (1), 118-129, 2016 | 308 | 2016 |
Dario AlessiMRC Protein Phosphorylation and Ubiquitylation Units, University of Dundee在 dundee.ac.uk 的电子邮件经过验证
