Mechanism of tissue‐specific farnesoid X receptor in suppressing the expression of genes in bile‐acid synthesis in mice B Kong, L Wang, JYL Chiang, Y Zhang, CD Klaassen, GL Guo Hepatology 56 (3), 1034-1043, 2012 | 431 | 2012 |
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin L Chen, Y Shu, X Liang, EC Chen, SW Yee, AA Zur, S Li, L Xu, ... Proceedings of the National Academy of Sciences 111 (27), 9983-9988, 2014 | 233 | 2014 |
Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity T Li, JM Francl, S Boehme, A Ochoa, Y Zhang, CD Klaassen, SK Erickson, ... Journal of Biological Chemistry 287 (3), 1861-1873, 2012 | 231 | 2012 |
Effect of bile duct ligation on bile acid composition in mouse serum and liver Y Zhang, JY Hong, CE Rockwell, BL Copple, H Jaeschke, CD Klaassen Liver International 32 (1), 58-69, 2012 | 205 | 2012 |
Dose-response of five bile acids on serum and liver bile Acid concentrations and hepatotoxicty in mice P Song, Y Zhang, CD Klaassen Toxicological Sciences 123 (2), 359-367, 2011 | 160 | 2011 |
Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice [S] Y Zhang, CD Klaassen Journal of lipid research 51 (11), 3230-3242, 2010 | 154 | 2010 |
Effect of various antibiotics on modulation of intestinal microbiota and bile acid profile in mice Y Zhang, PB Limaye, HJ Renaud, CD Klaassen Toxicology and applied pharmacology 277 (2), 138-145, 2014 | 151 | 2014 |
Organic anion–transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2‐null mice IL Csanaky, H Lu, Y Zhang, K Ogura, S Choudhuri, CD Klaassen Hepatology 53 (1), 272-281, 2011 | 139 | 2011 |
Importance of large intestine in regulating bile acids and glucagon-like peptide-1 in germ-free mice FP Selwyn, IL Csanaky, Y Zhang, CD Klaassen Drug Metabolism and Disposition 43 (10), 1544-1556, 2015 | 96 | 2015 |
Dose-response effect of berberine on bile acid profile and gut microbiota in mice Y Guo, YC Zhang, WH Huang, FP Selwyn, CD Klaassen BMC complementary and alternative medicine 16, 1-12, 2016 | 73 | 2016 |
Transcription factor-mediated regulation of carboxylesterase enzymes in livers of mice Y Zhang, X Cheng, L Aleksunes, CD Klaassen Drug Metabolism and Disposition 40 (6), 1191-1197, 2012 | 62 | 2012 |
Reduced renal clearance of cefotaxime in asians with a low-frequency polymorphism of OAT3 (SLC22A8) SW Yee, AN Nguyen, C Brown, RM Savic, Y Zhang, RA Castro, CD Cropp, ... Journal of pharmaceutical sciences 102 (9), 3451-3457, 2013 | 54 | 2013 |
The Nrf2 activator oltipraz also activates the constitutive androstane receptor MD Merrell, JP Jackson, LM Augustine, CD Fisher, AL Slitt, JM Maher, ... Drug Metabolism and Disposition 36 (8), 1716-1721, 2008 | 53 | 2008 |
Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice J Liu, YF Lu, Y Zhang, KC Wu, F Fan, CD Klaassen Toxicology and applied pharmacology 272 (3), 816-824, 2013 | 51 | 2013 |
Prediction and validation of enzyme and transporter off-targets for metformin SW Yee, L Lin, M Merski, MJ Keiser, A Gupta, Y Zhang, HC Chien, ... Journal of pharmacokinetics and pharmacodynamics 42, 463-475, 2015 | 49 | 2015 |
Nrf2 protects against diquat-induced liver and lung injury KC Wu, Y Zhang, CD Klaassen Free radical research 46 (10), 1220-1229, 2012 | 48 | 2012 |
Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles L Gong, N Aranibar, YH Han, Y Zhang, L Lecureux, V Bhaskaran, ... Toxicological Sciences 122 (2), 587-597, 2011 | 47 | 2011 |
Hormonal regulation of Cyp4a isoforms in mouse liver and kidney Y Zhang, CD Klaassen Xenobiotica 43 (12), 1055-1063, 2013 | 42 | 2013 |
1H NMR and UHPLC/Q-Orbitrap-MS-Based Metabolomics Combined with 16S rRNA Gut Microbiota Analysis Revealed the Potential Regulation Mechanism of … LM Wang, P Wang, T Teka, YC Zhang, WZ Yang, Y Zhang, T Wang, ... Journal of Agricultural and Food Chemistry 68 (47), 14059-14070, 2020 | 40 | 2020 |
Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice Y Zhang, PB Limaye, LD Lehman-McKeeman, CD Klaassen PLoS One 7 (4), e34522, 2012 | 40 | 2012 |