Gut microbes contribute to variation in solid organ transplant outcomes in mice CM McIntosh, L Chen, A Shaiber, AM Eren, ML Alegre Microbiome 6, 1-12, 2018 | 66 | 2018 |
The combination of hypomethylating agents and histone deacetylase inhibitors produce marked synergy in preclinical models of T‐cell lymphoma E Marchi, KM Zullo, JE Amengual, M Kalac, D Bongero, CM McIntosh, ... British journal of haematology 171 (2), 215-226, 2015 | 63 | 2015 |
The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κB C Deng, M Lipstein, R Rodriguez, XOJ Serrano, C McIntosh, WY Tsai, ... Clinical Cancer Research 21 (1), 134-145, 2015 | 32 | 2015 |
Distinct graft-specific TCR avidity profiles during acute rejection and tolerance ML Miller, CM McIntosh, JB Williams, Y Wang, MK Hollinger, NJ Isaad, ... Cell reports 24 (8), 2112-2126, 2018 | 20 | 2018 |
Resilience of T cell-intrinsic dysfunction in transplantation tolerance ML Miller, CM McIntosh, Y Wang, L Chen, P Wang, YM Lei, MD Daniels, ... Proceedings of the National Academy of Sciences 116 (47), 23682-23690, 2019 | 15 | 2019 |
The pursuit of transplantation tolerance: new mechanistic insights PK Gupta, CM McIntosh, AS Chong, ML Alegre Cellular & Molecular Immunology 16 (4), 324-333, 2019 | 14 | 2019 |
Evolving approaches in the identification of allograft-reactive T and B cells in mice and humans JS Young, C McIntosh, ML Alegre, AS Chong Transplantation 101 (11), 2671-2681, 2017 | 13 | 2017 |
Exercise increases skin graft resistance to rejection VE Rael, L Chen, CM McIntosh, ML Alegre American Journal of Transplantation 19 (5), 1560-1567, 2019 | 8 | 2019 |
The PI3K delta inhibitor TGR-1202 and proteasome inhibitor carfilzomib are highly synergistic in killing human B-and T-cell lymphoma cells C Deng, C McIntosh, R Rodriguez, P Sportelli, HP Miskin, S Vakkalanka, ... Blood 122 (21), 4421, 2013 | 7 | 2013 |
Combination of epigenetic agents synergistically reverse the malignant phenotype in models of T-cell lymphoma E Marchi, M Kalac, DC Bongero, CM McIntosh, LK Fogli, L Scotto, M Rossi, ... Blood 118 (21), 2727, 2011 | 5 | 2011 |
Oral administration of the commensal Alistipes onderdonkii prolongs allograft survival Z Li, M Rasic, M Kwan, M Sepulveda, C McIntosh, V Shastry, L Chen, ... American Journal of Transplantation 23 (2), 272-277, 2023 | 4 | 2023 |
Teamwork by IL-10+ and IL-35+ Tregs CM McIntosh, ML Alegre American Journal of Transplantation 19 (8), 2147, 2019 | 3 | 2019 |
Reduced Satb1 expression predisposes CD4+ T conventional cells to Treg suppression and promotes transplant survival PK Gupta, JB Allocco, JM Fraipont, ML McKeague, P Wang, MS Andrade, ... Proceedings of the National Academy of Sciences 119 (40), e2205062119, 2022 | 2 | 2022 |
Combination of selective HDAC inhibitors that target specific HDAC isoforms synergistically inhibits T cell lymphoma C Deng, R Rodriguez, C McIntosh, E Holson, C Karan, M Lipstein, ... Blood 122 (21), 5142, 2013 | 2 | 2013 |
Low-affinity CD8+ T cells provide interclonal help to high-affinity CD8+ T cells to augment alloimmunity P Wang, L Chen, R Mora-Cartin, CM McIntosh, H Sattar, AS Chong, ... American Journal of Transplantation 24 (6), 933-943, 2024 | 1 | 2024 |
Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection CM McIntosh, JB Allocco, P Wang, ML McKeague, A Cassano, Y Wang, ... The Journal of Clinical Investigation 133 (21), 2023 | 1 | 2023 |
Oral alloantigen exposure promotes donor-specific tolerance in a mouse model of minor-mismatched skin transplantation P Wang, L Chen, CM McIntosh, JI Lane, R Li, SZ Xie, H Sattar, ... American Journal of Transplantation 22 (10), 2348-2359, 2022 | 1 | 2022 |
Giving effector/memory T cells a new (suppressive) purpose CM Mcintosh, ML Alegre American Journal of Transplantation 20 (3), 625-625, 2020 | 1 | 2020 |
Variegated levels of alloreactive T cell dysfunction in transplantation tolerance determine graft vulnerability to infection-triggered rejection JB Allocco, C McIntosh, P Wang, M McKeague, Y Wang, A Cassano, ... The Journal of Immunology 210 (1_Supplement), 173.08-173.08, 2023 | | 2023 |
Tregs are important to maintain CD4+ Tconv hypofunction in allograft tolerance. A Cassano, R Mora-Cartin, P Wang, Y Wang, C McIntosh, ASF Chong, ... The Journal of Immunology 210 (1_Supplement), 173.44-173.44, 2023 | | 2023 |