Universal strategies in research and drug discovery based on protein-fragment complementation assays SW Michnick, PH Ear, EN Manderson, I Remy, E Stefan Nature reviews Drug discovery 6 (7), 569-582, 2007 | 392 | 2007 |
Purification and characterization of recombinant microsomal prostaglandin E synthase-1 M Ouellet, JP Falgueyret, PH Ear, A Pen, JA Mancini, D Riendeau, ... Protein expression and purification 26 (3), 489-495, 2002 | 71 | 2002 |
Maternal nicotinamide riboside enhances postpartum weight loss, juvenile offspring development, and neurogenesis of adult offspring PH Ear, A Chadda, SB Gumusoglu, MS Schmidt, S Vogeler, J Malicoat, ... Cell reports 26 (4), 969-983. e4, 2019 | 69 | 2019 |
A general life-death selection strategy for dissecting protein functions PH Ear, SW Michnick Nature methods 6 (11), 813-816, 2009 | 64 | 2009 |
A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein–protein interactions in living cells SW Michnick, PH Ear, C Landry, MK Malleshaiah, V Messier Methods in enzymology 470, 335-368, 2010 | 61 | 2010 |
Protein-fragment complementation assays for large-scale analysis, functional dissection and dynamic studies of protein–protein interactions in living cells SW Michnick, PH Ear, C Landry, MK Malleshaiah, V Messier Signal Transduction Protocols, 395-425, 2011 | 55 | 2011 |
PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades E Stefan, MK Malleshaiah, B Breton, PH Ear, V Bachmann, M Beyermann, ... Nature communications 2 (1), 598, 2011 | 50 | 2011 |
Gene expression signatures identify novel therapeutics for metastatic pancreatic neuroendocrine tumors AT Scott, M Weitz, PJ Breheny, PH Ear, B Darbro, BJ Brown, TA Braun, ... Clinical Cancer Research 26 (8), 2011-2021, 2020 | 47 | 2020 |
Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets CK Maharjan, PH Ear, CG Tran, JR Howe, C Chandrasekharan, ... Cancers 13 (20), 5117, 2021 | 39 | 2021 |
Dissection of Cdk1–cyclin complexes in vivo PH Ear, MJ Booth, D Abd-Rabbo, J Kowarzyk Moreno, C Hall, D Chen, ... Proceedings of the National Academy of Sciences 110 (39), 15716-15721, 2013 | 22 | 2013 |
Biological production of nad precursors and analogs DA Sinclair, PH Ear US Patent App. 15/034,953, 2016 | 21 | 2016 |
Effect of bacterial contamination in bile on pancreatic cancer cell survival HR Shrader, AM Miller, A Tomanek-Chalkley, A McCarthy, KL Coleman, ... Surgery 169 (3), 617-622, 2021 | 20 | 2021 |
It is time to rethink biomarkers for surveillance of small bowel neuroendocrine tumors CG Tran, SK Sherman, AT Scott, PH Ear, C Chandrasekharan, AM Bellizzi, ... Annals of surgical oncology 28, 732-741, 2021 | 19 | 2021 |
Establishment and characterization of small bowel neuroendocrine tumor spheroids PH Ear, G Li, M Wu, E Abusada, AM Bellizzi, JR Howe JoVE (Journal of Visualized Experiments), e60303, 2019 | 16 | 2019 |
Management of duodenal neuroendocrine tumors: surgical versus endoscopic mucosal resection CG Tran, SK Sherman, MO Suraju, A Nayyar, H Gerke, RGE Abiad, ... Annals of surgical oncology 29, 75-84, 2022 | 12 | 2022 |
Establishment of novel neuroendocrine carcinoma patient-derived xenograft models for receptor peptide-targeted therapy CG Tran, LC Borbon, JL Mudd, E Abusada, S AghaAmiri, SC Ghosh, ... Cancers 14 (8), 1910, 2022 | 11 | 2022 |
Site‐directed mutagenesis of the type II TGF‐β receptor indicates a ligand‐binding site distinct from that of the type II activin receptor A Guimond, T Sulea, A Pen, P Ear, MD O'Connor-McCourt FEBS letters 515 (1-3), 13-19, 2002 | 11 | 2002 |
Is there a role for surgical resection of grade 3 neuroendocrine neoplasms? LC Borbon, CG Tran, SK Sherman, PH Ear, C Chandrasekharan, ... Annals of surgical oncology 29 (11), 6936-6946, 2022 | 8 | 2022 |
High-contrast detection of somatostatin receptor subtype-2 for fluorescence-guided surgery S Hernandez Vargas, S AghaAmiri, SC Ghosh, MP Luciano, LC Borbon, ... Molecular pharmaceutics 19 (11), 4241-4253, 2022 | 8 | 2022 |
Metastatic pancreatic neuroendocrine tumors have decreased somatostatin expression and increased Akt signaling CG Tran, AT Scott, G Li, SK Sherman, PH Ear, JR Howe Surgery 169 (1), 155-161, 2021 | 8 | 2021 |