A mechanical switch couples T cell receptor triggering to the cytoplasmic juxtamembrane regions of CD3ζζ MS Lee, CR Glassman, NR Deshpande, HB Badgandi, HL Parrish, ... Immunity 43 (2), 227-239, 2015 | 120 | 2015 |
Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected C Liu, T Miyajima, G Melangath, T Miyai, S Vasanth, N Deshpande, ... Proceedings of the National Academy of Sciences 117 (1), 573-583, 2020 | 88 | 2020 |
Activation of PINK1-parkin–mediated mitophagy degrades mitochondrial quality control proteins in Fuchs endothelial corneal dystrophy T Miyai, S Vasanth, G Melangath, N Deshpande, V Kumar, AS Benischke, ... The American Journal of Pathology 189 (10), 2061-2076, 2019 | 35 | 2019 |
Self-recognition drives the preferential accumulation of promiscuous CD4+ T-cells in aged mice NR Deshpande, HL Parrish, MS Kuhns Elife 4, e05949, 2015 | 35 | 2015 |
A transmembrane domain GGxxG motif in CD4 contributes to its Lck-independent function but does not mediate CD4 dimerization HL Parrish, CR Glassman, MM Keenen, NR Deshpande, MP Bronnimann, ... PLoS One 10 (7), e0132333, 2015 | 26 | 2015 |
A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells S Kobayashi, MA Thelin, HL Parrish, NR Deshpande, MS Lee, ... Proceedings of the National Academy of Sciences 117 (46), 28950-28959, 2020 | 22 | 2020 |
Loss of NQO1 generates genotoxic estrogen-DNA adducts in Fuchs Endothelial Corneal Dystrophy T Miyajima, G Melangath, S Zhu, N Deshpande, S Vasanth, B Mondal, ... Free Radical Biology and Medicine 147, 69-79, 2020 | 20 | 2020 |
Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling A Pawar, JA Meier, A Dasgupta, N Diwanji, N Deshpande, K Saxena, ... Cellular signalling 28 (9), 1225-1236, 2016 | 20 | 2016 |
Cell cycle re-entry and arrest in G2/M phase induces senescence and fibrosis in Fuchs Endothelial Corneal Dystrophy TL White, N Deshpande, V Kumar, AG Gauthier, UV Jurkunas Free Radical Biology and Medicine 164, 34-43, 2021 | 19 | 2021 |
The CD4 and CD3δε Cytosolic Juxtamembrane Regions Are Proximal within a Compact TCR–CD3–pMHC–CD4 Macrocomplex CR Glassman, HL Parrish, NR Deshpande, MS Kuhns The Journal of Immunology 196 (11), 4713-4722, 2016 | 11 | 2016 |
Increased corneal endothelial cell migration in Fuchs endothelial corneal dystrophy: a live cell imaging study SO Tone, A Wylegala, M Böhm, G Melangath, N Deshpande, ... Ophthalmology Science 1 (1), 100006, 2021 | 7 | 2021 |
The Neuropeptide α-Melanocyte–Stimulating Hormone Prevents Persistent Corneal Edema Following Injury H Alemi, S Wang, T Blanco, F Kahale, RB Singh, G Ortiz, A Musayeva, ... The American Journal of Pathology 194 (1), 150-164, 2024 | 5 | 2024 |
Dysregulation of DNA repair genes in Fuchs endothelial corneal dystrophy S Ashraf, N Deshpande, S Vasanth, G Melangath, RJ Wong, Y Zhao, ... Experimental Eye Research 231, 109499, 2023 | 2 | 2023 |
MAVS regulates the quality of the antibody response to West-Nile Virus M O’Ketch, S Williams, C Larson, JL Uhrlaub, R Wong, B Hall, ... PLoS Pathogens 16 (10), e1009009, 2020 | 2 | 2020 |
Treatment with Neuropeptide Alpha-Melanocyte Stimulating Hormone Suppresses Progression of Fuchs Dystrophy in a UV-Induced Mouse Model F Kahale, N Deshpande, H Alemi, A Naderi, S Wang, T Blanco, ... Investigative Ophthalmology & Visual Science 64 (8), 635-635, 2023 | 1 | 2023 |
Effect of ROCK inhibitor on cell migration in fuchs endothelial corneal dystrophy M Parekh, A Miall, N Deshpande, UV Jurkunas Investigative Ophthalmology & Visual Science 63 (7), 3634–A0199-3634–A0199, 2022 | 1 | 2022 |
Efficacy of Neuropeptide Alpha-Melanocyte Stimulating Hormone (α-MSH) on Corneal Endothelial Cell Regeneration following Injury H Alemi, S Wang, N Deshpande, T Blanco, F Kahale, G Ortiz, ... Investigative Ophthalmology & Visual Science 63 (7), 3645–A0210-3645–A0210, 2022 | 1 | 2022 |
Defective DNA Repair in Fuchs endothelial corneal dystrophy N Deshpande, G Melangath, S Vasanth, M Price, F Price, UV Jurkunas Investigative Ophthalmology & Visual Science 62 (8), 838-838, 2021 | 1 | 2021 |
UV-A light induces G2/M phase arrest and subsequent endothelial-mesenchymal transition in Fuchs Endothelial Corneal Dystrophy T White, N Deshpande, UV Jurkunas Investigative ophthalmology & visual science 60 (9), 2179-2179, 2019 | 1 | 2019 |
NQO1 downregulation generates genotoxic DNA adducts in in vitro FECD model T Miyajima, S Vasanth, G Melangath, N Deshpande, Y Chen, M Zahid, ... Investigative ophthalmology & visual science 60 (9), 2177-2177, 2019 | 1 | 2019 |