Drivers and sites of diversity in the DNA adenine methylomes of 93 Mycobacterium tuberculosis complex clinical isolates SJ Modlin, D Conkle-Gutierrez, C Kim, SN Mitchell, C Morrissey, ... Elife 9, e58542, 2020 | 30 | 2020 |
SMRT genome assembly corrects reference errors, resolving the genetic basis of virulence in Mycobacterium tuberculosis A Elghraoui, SJ Modlin, F Valafar BMC genomics 18, 1-14, 2017 | 28 | 2017 |
Atypical genetic basis of pyrazinamide resistance in monoresistant Mycobacterium tuberculosis SJ Modlin, T Marbach, J Werngren, M Mansjö, SE Hoffner, F Valafar Antimicrobial Agents and Chemotherapy 65 (6), 10.1128/aac. 01916-20, 2021 | 24 | 2021 |
Exact mapping of Illumina blind spots in the Mycobacterium tuberculosis genome reveals platform-wide and workflow-specific biases SJ Modlin, C Robinhold, C Morrissey, SN Mitchell, SM Ramirez-Busby, ... Microbial Genomics 7 (3), 000465, 2021 | 21 | 2021 |
Pyrazinamide susceptibility is driven by activation of the SigE-dependent cell envelope stress response in mycobacterium tuberculosis JM Thiede, NA Dillon, MD Howe, R Aflakpui, SJ Modlin, SE Hoffner, ... MBio 13 (1), e00439-21, 2022 | 17 | 2022 |
Structure-aware Mycobacterium tuberculosis functional annotation uncloaks resistance, metabolic, and virulence genes SJ Modlin, A Elghraoui, D Gunasekaran, AM Zlotnicki, NA Dillon, ... MSystems 6 (6), e00673-21, 2021 | 8 | 2021 |
Distribution of common and rare genetic markers of second-line-Injectable-drug resistance in Mycobacterium tuberculosis revealed by a genome-wide association study D Conkle-Gutierrez, C Kim, SM Ramirez-Busby, SJ Modlin, M Mansjö, ... Antimicrobial Agents and Chemotherapy 66 (6), e02075-21, 2022 | 7 | 2022 |
Pyrazinamide-resistant tuberculosis obscured from common targeted molecular diagnostics SJ Modlin, M Mansjö, J Werngren, CM Ejike, SE Hoffner, F Valafar Drug Resistance Updates 68, 100959, 2023 | 4 | 2023 |
Resolving the hypotheticome: annotating m. tuberculosis gene function through bibliomic reconciliation and structural modeling SJ Modlin, D Gunasekaran, AM Zlotnicki, A Elghraoui, N Kuo, CK Chan, ... Preprint at https://doi. org/10.1101/358986, 2018 | 4 | 2018 |
Compositions and methods for treating or ameliorating infections F Valafar, SJ Modlin, SM Radecke, E Westin, D Gunasekaran US Patent App. 17/914,662, 2023 | 2 | 2023 |
The DNA Methylome of Drug-Resistant Mycobacterium tuberculosis SJ Modlin San Diego State University, 2018 | 2 | 2018 |
Rare alternative second line injectable drug resistance markers identified by gene-wise genome wide association in M. tuberculosis with unexplained resistance D Conkle-Gutierrez, C Kim, SM Ramirez-Busby, SJ Modlin, M Mansjö, ... bioRxiv, 2021.11. 23.469801, 2021 | 1 | 2021 |
Compositions and methods for treating or ameliorating a mycobacterium tuberculosis infection F Valafar, S Modlin, D Conkle-gutierrez US Patent App. 17/787,114, 2023 | | 2023 |
Pyrazinamide action is driven by the cell envelope stress response in Mycobacterium tuberculosis JM Thiede, NA Dillon, MD Howe, R Aflakpui, SJ Modlin, SE Hoffner, ... bioRxiv, 2021.02. 17.431758, 2021 | | 2021 |
Structure-aware M. tuberculosis functional annotation uncloaks resistance, metabolic, and virulence genes SJ Modlin, A Elghraoui, D Gunasekaran, AM Zlotnicki, NA Dillon, ... bioRxiv, 358986, 2018 | | 2018 |
Lineage-specific Copy Number and Distribution of IS6110 in de novo-assembled Mtb Isolates S Modlin, S Patel, L Fink, A Elghraoui, S Hoffner, F Valafar | | |