| Regulation of gene expression by insulin RM O'Brien, DK Granner Physiological reviews 76 (4), 1109-1161, 1996 | 657 | 1996 |
| Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription RM O'Brien, PC Lucas, CD Forest, MA Magnuson, DK Granner Science 249 (4968), 533-537, 1990 | 418 | 1990 |
| Regulation of gene expression by insulin. RM O'Brien, DK Granner Biochemical Journal 278 (Pt 3), 609, 1991 | 368 | 1991 |
| Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin: the role of winged helix/forkhead proteins RK Hall, T Yamasaki, T Kucera, M Waltner-Law, R O'Brien, DK Granner Journal of Biological Chemistry 275 (39), 30169-30175, 2000 | 348 | 2000 |
| Hepatic nuclear factor 3-and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes RM O'Brien, EL Noisin, A Suwanichkul, T Yamasaki, PC Lucas, JC Wang, ... Molecular and cellular biology 15 (3), 1747-1758, 1995 | 275 | 1995 |
| Insulin-regulated gene expression RM O'brien, RS Streeper, JE Ayala, BT Stadelmaier, LA Hornbuckle Biochemical Society Transactions 29 (4), 552-558, 2001 | 266 | 2001 |
| Glucose-6-phosphatase catalytic subunit gene family JC Hutton, RM O'Brien Journal of Biological Chemistry 284 (43), 29241-29245, 2009 | 222 | 2009 |
| Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion LD Pound, SA Sarkar, RKP Benninger, Y Wang, A Suwanichkul, ... Biochemical Journal 421 (3), 371-376, 2009 | 219 | 2009 |
| Molecular physiology and genetics of NIDDM: importance of metabolic staging DK Granner, RM O'Brien Diabetes Care 15 (3), 369-395, 1992 | 200 | 1992 |
| Zinc transporter 8 (ZnT8) and β cell function HW Davidson, JM Wenzlau, RM O’Brien Trends in Endocrinology & Metabolism 25 (8), 415-424, 2014 | 194 | 2014 |
| Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by … C Sutherland, RM O'Brien, DK Granner Journal of Biological Chemistry 270 (26), 15501-15506, 1995 | 189 | 1995 |
| A retinoic acid response element is part of a pleiotropic domain in the phosphoenolpyruvate carboxykinase gene. PC Lucas, RM O'Brien, JA Mitchell, CM Davis, E Imai, BM Forman, ... Proceedings of the National Academy of Sciences 88 (6), 2184-2188, 1991 | 187 | 1991 |
| The glucose-6-phosphatase catalytic subunit gene promoter contains both positive and negative glucocorticoid response elements BT Vander Kooi, H Onuma, JK Oeser, CA Svitek, SR Allen, ... Molecular endocrinology 19 (12), 3001-3022, 2005 | 182 | 2005 |
| A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin RS Streeper, CA Svitek, S Chapman, LE Greenbaum, R Taub, RM O'Brien Journal of Biological Chemistry 272 (18), 11698-11701, 1997 | 177 | 1997 |
| Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway (∗) RA Gabbay, C Sutherland, L Gnudi, BB Kahn, RM O'Brien, DK Granner, ... Journal of Biological Chemistry 271 (4), 1890-1897, 1996 | 163 | 1996 |
| The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go RM O'Brien, MD Houslay, G Milligan, K Siddle FEBS letters 212 (2), 281-288, 1987 | 151 | 1987 |
| Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response … JE Ayala, RS Streeper, JS Desgrosellier, SK Durham, A Suwanichkul, ... Diabetes 48 (9), 1885-1889, 1999 | 150 | 1999 |
| Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein. SD Arden, T Zahn, S Steegers, S Webb, B Bergman, RM O'Brien, ... Diabetes 48 (3), 531-542, 1999 | 140 | 1999 |
| Insulin’s direct hepatic effect explains the inhibition of glucose production caused by insulin secretion DS Edgerton, G Kraft, M Smith, B Farmer, PE Williams, KC Coate, ... JCI insight 2 (6), 2017 | 130 | 2017 |
| PEPCK gene as model of inhibitory effects of insulin on gene transcription RM O'Brien, DK Granner Diabetes Care 13 (3), 327-339, 1990 | 130 | 1990 |
