| Human and Helicobacter pylori coevolution shapes the risk of gastric disease N Kodaman, A Pazos, BG Schneider, MB Piazuelo, R Mera, RS Sobota, ... Proceedings of the National Academy of Sciences 111 (4), 1455-1460, 2014 | 308 | 2014 |
| Phylogeographic origin of Helicobacter pylori is a determinant of gastric cancer risk T de Sablet, MB Piazuelo, CL Shaffer, BG Schneider, M Asim, ... Gut 60 (9), 1189-1195, 2011 | 194 | 2011 |
| Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface CL Shaffer, JA Gaddy, JT Loh, EM Johnson, S Hill, EE Hennig, ... PLoS Pathogens 7 (9), e1002237, 2011 | 180 | 2011 |
| Genome sequence analysis of Helicobacter pylori strains associated with gastric ulceration and gastric cancer MS McClain, CL Shaffer, DA Israel, RM Peek, TL Cover BMC Genomics 10 (1), 3, 2009 | 134 | 2009 |
| Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori–infected children C Serrano, SW Wright, D Bimczok, CL Shaffer, TL Cover, A Venegas, ... Mucosal Immunology 6 (5), 950, 2013 | 123* | 2013 |
| Pathogenic H elicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system MG Varga, CL Shaffer, JC Sierra, G Suarez, MB Piazuelo, ME Whitaker, ... Oncogene 35 (48), 6262-6269, 2016 | 118 | 2016 |
| Adhesive fiber stratification in uropathogenic Escherichia coli biofilms unveils oxygen-mediated control of type 1 pili KA Floyd, JL Moore, AR Eberly, JAD Good, CL Shaffer, H Zaver, ... PLoS Pathogens 11 (3), e1004697, 2015 | 102 | 2015 |
| Strong cross-system interactions drive the activation of the QseB response regulator in the absence of its cognate sensor KR Guckes, M Kostakioti, EJ Breland, AP Gu, CL Shaffer, CR Martinez III, ... Proceedings of the National Academy of Sciences 110 (41), 16592-16597, 2013 | 102 | 2013 |
| In vivo structures of the Helicobacter pylori cag type IV secretion system YW Chang, CL Shaffer, LA Rettberg, D Ghosal, GJ Jensen Cell Reports 23 (3), 673-681, 2018 | 83 | 2018 |
| Molecular evolution of the Helicobacter pylori vacuolating toxin gene vacA KA Gangwer, CL Shaffer, S Suerbaum, DB Lacy, TL Cover, ... Journal of Bacteriology 192 (23), 6126-6135, 2010 | 82 | 2010 |
| Analysis of cagA in Helicobacter pylori Strains from Colombian Populations with Contrasting Gastric Cancer Risk Reveals a Biomarker for Disease Severity JT Loh, CL Shaffer, MB Piazuelo, LE Bravo, MS McClain, P Correa, ... Cancer epidemiology, biomarkers & prevention 20 (10), 2237-2249, 2011 | 81 | 2011 |
| Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli SE Greene, JS Pinkner, E Chorell, KW Dodson, CL Shaffer, MS Conover, ... MBio 5 (6), 10.1128/mbio. 02038-14, 2014 | 77 | 2014 |
| Purine biosynthesis metabolically constrains intracellular survival of uropathogenic Escherichia coli CL Shaffer, EW Zhang, AG Dudley, BREA Dixon, KR Guckes, EJ Breland, ... Infection and Immunity 85 (1), e00471-16, 2017 | 55 | 2017 |
| Peptidomimetic small molecules disrupt type IV secretion system activity in diverse bacterial pathogens CL Shaffer, JAD Good, S Kumar, KS Krishnan, JA Gaddy, JT Loh, ... MBio 7 (2), e00221-16, 2016 | 49 | 2016 |
| Comparative genomic analysis of East Asian and non-Asian Helicobacter pylori strains identifies rapidly evolving genes SS Duncan, PL Valk, MS McClain, CL Shaffer, JA Metcalf, SR Bordenstein, ... PloS One 8 (1), e55120, 2013 | 40 | 2013 |
| Inhibiting bacterial secretion systems in the fight against antibiotic resistance E Boudaher, CL Shaffer Medchemcomm 10 (5), 682-692, 2019 | 32 | 2019 |
| J-Western forms of Helicobacter pylori cagA constitute a distinct phylogenetic group with a widespread geographic distribution SS Duncan, PL Valk, CL Shaffer, SR Bordenstein, TL Cover Journal of Bacteriology, JB. 06340-11, 2012 | 29 | 2012 |
| In situ imaging of bacterial outer membrane projections and associated protein complexes using electron cryo-tomography M Kaplan, G Chreifi, LA Metskas, J Liedtke, CR Wood, CM Oikonomou, ... Elife 10, e73099, 2021 | 20 | 2021 |
| Transcriptional effects of melatonin on the gut commensal bacterium Klebsiella aerogenes KB Graniczkowska, CL Shaffer, VM Cassone Genomics 114 (2), 110321, 2022 | 14 | 2022 |
| Immunostimulatory membrane proteins potentiate H. pylori-induced carcinogenesis by enabling CagA translocation MG Varga, CR Wood, J Butt, ME Ryan, WC You, K Pan, T Waterboer, ... Gut Microbes 13 (1), 1862613, 2021 | 14 | 2021 |
