Efficient total syntheses and biological activities of two teixobactin analogues A Parmar, A Iyer, CS Vincent, D Van Lysebetten, SH Prior, A Madder, ... Chemical communications 52 (36), 6060-6063, 2016 | 96 | 2016 |
Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant … A Parmar, R Lakshminarayanan, A Iyer, V Mayandi, ET Leng Goh, ... Journal of medicinal chemistry 61 (5), 2009-2017, 2018 | 95 | 2018 |
Mode of action of teixobactins in cellular membranes R Shukla, J Medeiros-Silva, A Parmar, BJA Vermeulen, S Das, AL Paioni, ... Nature communications 11 (1), 2848, 2020 | 89 | 2020 |
Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding A Parmar, A Iyer, SH Prior, DG Lloyd, ETL Goh, CS Vincent, ... Chemical Science 8 (12), 8183-8192, 2017 | 63 | 2017 |
Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities A Parmar, SH Prior, A Iyer, CS Vincent, D Van Lysebetten, E Breukink, ... Chemical Communications 53 (12), 2016-2019, 2017 | 57 | 2017 |
Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of l-allo-enduracididine with its isosteres A Parmar, A Iyer, DG Lloyd, CS Vincent, SH Prior, A Madder, EJ Taylor, ... Chemical Communications 53 (55), 7788-7791, 2017 | 44 | 2017 |
Cysteines and disulfide-bridged macrocyclic mimics of teixobactin analogues and their antibacterial activity evaluation against methicillin-resistant Staphylococcus aureus (MRSA) R Malkawi, A Iyer, A Parmar, DG Lloyd, ET Leng Goh, EJ Taylor, ... Pharmaceutics 10 (4), 183, 2018 | 15 | 2018 |
Analyzing mechanisms of action of antimicrobial peptides on bacterial membranes requires multiple complimentary assays and different bacterial strains X Wang, RAM van Beekveld, Y Xu, A Parmar, S Das, I Singh, E Breukink Biochimica et Biophysica Acta (BBA)-Biomembranes 1865 (6), 184160, 2023 | 9 | 2023 |
Development of teixobactin analogues containing hydrophobic, non-proteogenic amino acids that are highly potent against multidrug-resistant bacteria and biofilms A Parmar, R Lakshminarayanan, A Iyer, ETL Goh, TY To, JKH Yam, ... European Journal of Medicinal Chemistry 261, 115853, 2023 | 3 | 2023 |
New Teixobactin Analogues with a Total Lactam Ring G Scioli, L Marinaccio, M Bauer, W Kamysz, A Parmar, E Newire, I Singh, ... ACS Medicinal Chemistry Letters 14 (12), 1827-1832, 2023 | 3 | 2023 |
Stereoselective synthesis of protected l-allo-Enduracididine and l-Enduracididine via asymmetric nitroaldol reaction K Ohsawa, H Zhao, T Tokunaga, C Thomas, A Ganesan, Y Masuda, T Doi Synthesis 52 (06), 942-948, 2020 | 1 | 2020 |
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial PW Horby, A Roddick, E Spata, N Staplin, J Emberson, G Pessoa-Amorim, ... Lancet 397 (10274), 605-612, 2021 | | 2021 |
Synthesis of Teixobactin Analogues and Their Biological Evaluation A Parmar University of Lincoln, 2019 | | 2019 |
Cysteines and Disulfide-Bridged Macrocyclic Mimics of Teixobactin Analogues and Their Antibacterial Activity Evaluation against Methicillin-Resistant Staphylococcus Aureus (MRSA) I Singh, R Malkawi, A Iyer, A Parmar, D Lloyd, E Goh, E Taylor, S Sarmad, ... University of Lincoln, 2018 | | 2018 |
Teixobactins: a new class of 21 st century antibiotics to combat multidrug-resistant bacterial pathogens A Parmar, E Newire, A Iyer, R Lakshminarayanan, SH Prior, I Singh | | |