| The diverse structural landscape of quadruplexes HL Lightfoot, T Hagen, NJ Tatum, J Hall FEBS letters 593 (16), 2083-2102, 2019 | 119 | 2019 |
| Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition DJ Wood, S Korolchuk, NJ Tatum, LZ Wang, JA Endicott, MEM Noble, ... Cell chemical biology 26 (1), 121-130. e5, 2019 | 105 | 2019 |
| Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors PA Lochhead, JA Tucker, NJ Tatum, J Wang, D Oxley, AM Kidger, ... Nature communications 11 (1), 1383, 2020 | 45 | 2020 |
| New active leads for tuberculosis booster drugs by structure-based drug discovery NJ Tatum, JW Liebeschuetz, JC Cole, R Frita, A Herledan, AR Baulard, ... Organic & Biomolecular Chemistry 15 (48), 10245-10255, 2017 | 29 | 2017 |
| Chatterboxes: the structural and functional diversity of cyclins NJ Tatum, JA Endicott Seminars in cell & developmental biology 107, 4-20, 2020 | 23 | 2020 |
| Probing biological activity through structural modelling of ligand-receptor interactions of 2, 4-disubstituted thiazole retinoids H Haffez, DR Chisholm, NJ Tatum, R Valentine, C Redfern, E Pohl, ... Bioorganic & medicinal chemistry 26 (8), 1560-1572, 2018 | 17 | 2018 |
| FEN1 blockade for platinum chemo-sensitization and synthetic lethality in epithelial ovarian cancers KA Mesquita, R Ali, R Doherty, MS Toss, I Miligy, A Alblihy, D Dorjsuren, ... Cancers 13 (8), 1866, 2021 | 16 | 2021 |
| Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation M Salamina, BC Montefiore, M Liu, DJ Wood, R Heath, JR Ault, LZ Wang, ... Journal of molecular biology 433 (5), 166795, 2021 | 13 | 2021 |
| Structural and docking studies of potent ethionamide boosters NJ Tatum, B Villemagne, N Willand, B Deprez, JW Liebeschuetz, ... Acta Crystallographica Section C: Crystal Structure Communications 69 (11 …, 2013 | 13 | 2013 |
| Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers A Alblihy, R Ali, M Algethami, A Shoqafi, MS Toss, J Brownlie, NJ Tatum, ... NPJ precision oncology 6 (1), 51, 2022 | 10 | 2022 |
| Synthesis and molecular structure of a perfluorinated pyridyl carbanion N Colgin, NJ Tatum, E Pohl, SL Cobb, G Sandford Journal of Fluorine Chemistry 133, 33-37, 2012 | 10 | 2012 |
| Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds NJ Tatum, F Duarte, SCL Kamerlin, E Pohl The Journal of Physical Chemistry Letters 10, 2244-2249, 2019 | 7 | 2019 |
| Synthesis, Ni (II) Schiff base complexation and structural analysis of fluorinated analogs of the ligand (S)-2-[N-(N′-benzylprolyl) amino] benzophenone (BPB) NJ Tatum, DS Yufit, SL Cobb, CR Coxon Journal of Fluorine Chemistry 173, 77-83, 2015 | 6 | 2015 |
| An open-source molecular builder and free energy preparation workflow MK Bieniek, B Cree, R Pirie, JT Horton, NJ Tatum, DJ Cole Communications chemistry 5 (1), 136, 2022 | 5 | 2022 |
| Crystallographic fragment screening in academic cancer drug discovery MP Martin, JA Endicott, MEM Noble, NJ Tatum Methods in Enzymology 690, 211-234, 2023 | 1 | 2023 |
| Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction I Hope, MP Martin, MJ Waring, MEM Noble, JA Endicott, NJ Tatum bioRxiv, 2024.06. 03.596235, 2024 | | 2024 |
| Discovery by Virtual Screening of Ethionamide Boosters for Tuberculosis Treatment N TATUM Durham University, 2015 | | 2015 |
| Crystallographic Studies for Structure-Based Drug Design N TATUM Durham University, 2012 | | 2012 |
Martin NobleProfessor of Structural Biology and Anticancer Drug Design在 ncl.ac.uk 的电子邮件经过验证
