Influence of mus201 and mus308 mutations of Drosophila melanogaster on the genotoxicity of model chemicals in somatic cells in vivo measured with the comet assay C Bilbao, JA Ferreiro, MA Comendador, LM Sierra Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 503 (1 …, 2002 | 83 | 2002 |
In vivo detection of DNA adducts induced by cisplatin using capillary HPLC–ICP-MS and their correlation with genotoxic damage in Drosophila melanogaster D García Sar, M Montes-Bayón, L Aguado Ortiz, E Blanco-González, ... Analytical and bioanalytical chemistry 390, 37-44, 2008 | 69 | 2008 |
Quantitative evaluation of cellular uptake, DNA incorporation and adduct formation in cisplatin sensitive and resistant cell lines: Comparison of different Pt-containing drugs M Corte-Rodríguez, M Espina, LM Sierra, E Blanco, T Ames, ... Biochemical Pharmacology 98 (1), 69-77, 2015 | 63 | 2015 |
DNA damage, and repair in mutagenesis and carcinogenesis: implications of structure-activity relationships for cross-species extrapolation EW Vogel, MJM Nivard, LAB Ballering, H Bartsch, A Barbin, J Nair, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 353 (1 …, 1996 | 55 | 1996 |
The w/w+ SMART assay of Drosophila melanogaster detects the genotoxic effects of reactive oxygen species inducing compounds I Gaivão, LM Sierra, MA Comendador Mutation Research/Genetic Toxicology and Environmental Mutagenesis 440 (2 …, 1999 | 54 | 1999 |
Drosophila comet assay: insights, uses, and future perspectives I Gaivão, LM Sierra Frontiers in genetics 5, 304, 2014 | 53 | 2014 |
New structures and gating of voltage-dependent potassium (Kv) channels and their relatives: a multi-domain and dynamic question F Barros, LA Pardo, P Domínguez, LM Sierra, P De la Peña International Journal of Molecular Sciences 20 (2), 248, 2019 | 40 | 2019 |
Acrolein genotoxicity in Drosophila melanogaster. I. Somatic and germinal mutagenesis under proficient repair conditions LM Sierra, AR Barros, M Garcia, JA Ferreiro, MA Comendador Mutation Research/Genetic Toxicology 260 (3), 247-256, 1991 | 39 | 1991 |
The EAG Voltage-Dependent K+ Channel Subfamily: Similarities and Differences in Structural Organization and Gating F Barros, P de la Peña, P Domínguez, LM Sierra, LA Pardo Frontiers in pharmacology 11, 411, 2020 | 35 | 2020 |
Relationships between cisplatin-induced adducts and DNA strand-breaks, mutation and recombination in vivo in somatic cells of Drosophila melanogaster, under different … DG Sar, L Aguado, MM Bayón, MA Comendador, EB González, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 741 (1-2 …, 2012 | 35 | 2012 |
Reduction of cisplatin-induced nephrotoxicity in vivo by selenomethionine: the effect on cisplatin–DNA adducts D García Sar, M Montes-Bayón, E Blanco González, LM Sierra Zapico, ... Chemical research in toxicology 24 (6), 896-904, 2011 | 35 | 2011 |
Somatic recombination, gene amplification and cancer. C Ramel, H Cederberg, J Magnusson, E Vogel, AT Natarajan, ... Mutation research 353 (1-2), 85-107, 1996 | 35 | 1996 |
Quantitative Profiling of in Vivo Generated Cisplatin− DNA Adducts Using Different Isotope Dilution Strategies D García Sar, M Montes-Bayón, E Blanco González, LM Sierra, L Aguado, ... Analytical chemistry 81 (23), 9553-9560, 2009 | 31 | 2009 |
The hypermutability conferred by the mus308 mutation of Drosophila is not specific for cross-linking agents I Aguirrezabalaga, LM Sierra, MA Comendador Mutation Research/DNA Repair 336 (3), 243-250, 1995 | 26 | 1995 |
In vivo repair of ENU-induced oxygen alkylation damage by the nucleotide excision repair mechanism in Drosophila melanogaster L Tosal, MA Comendador, LM Sierra Molecular Genetics and Genomics 265, 327-335, 2001 | 24 | 2001 |
N-Ethyl-N-nitrosourea predominantly induces mutations at AT base pairs in pre-meiotic germ cells of Drosophila males L Tosal, MA Comendador, L María Sierra Mutagenesis 13 (4), 375-380, 1998 | 23 | 1998 |
DNA base sequence changes induced by diethyl sulfate in postmeiotic male germ cells of Drosophila melanogaster LM Sierra, A Pastink, MJM Nivard, EW Vogel Molecular and General Genetics MGG 237, 370-374, 1993 | 22 | 1993 |
Genotoxicity and DNA Repair LM Sierra, I Gaivão New York, 2014 | 21 | 2014 |
Long-term biomonitoring of breast cancer patients under adjuvant chemotherapy: the comet assay as a possible predictive factor E Uriol, M Sierra, MA Comendador, J Fra, P Martínez-Camblor, AJ Lacave, ... Mutagenesis 28 (1), 39-48, 2013 | 21 | 2013 |
Cisplatin resistance in cell models: evaluation of metallomic and biological predictive biomarkers to address early therapy failure M Espina, M Corte-Rodríguez, L Aguado, M Montes-Bayón, MI Sierra, ... Metallomics 9 (5), 564-574, 2017 | 20 | 2017 |