| Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays I Valentin-Severin, L Le Hegarat, JC Lhuguenot, AM Le Bon, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 536 (1-2 …, 2003 | 168 | 2003 |
| Measuring DNA modifications with the comet assay: a compendium of protocols A Collins, P Møller, G Gajski, S Vodenková, A Abdulwahed, D Anderson, ... Nature protocols 18 (3), 929-989, 2023 | 128 | 2023 |
| In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop S Pfuhler, M Fellows, J van Benthem, R Corvi, R Curren, K Dearfield, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 723 (2 …, 2011 | 121 | 2011 |
| Genotoxicity of pesticide mixtures present in the diet of the French population V Graillot, N Takakura, LL Hegarat, V Fessard, M Audebert, JP Cravedi Environmental and molecular mutagenesis 53 (3), 173-184, 2012 | 103 | 2012 |
| Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays L Le Hegarat, J Dumont, R Josse, S Huet, R Lanceleur, A Mourot, JM Poul, ... Mutagenesis 25 (6), 555-560, 2010 | 85 | 2010 |
| Three-dimensional HepaRG spheroids as a liver model to study human genotoxicity in vitro with the single cell gel electrophoresis assay M Mandon, S Huet, E Dubreil, V Fessard, L Le Hégarat Scientific reports 9 (1), 10548, 2019 | 84 | 2019 |
| Genotoxicity of the marine toxin okadaic acid, in human Caco‐2 cells and in mice gut cells L Le Hégarat, AG Jacquin, E Bazin, V Fessard Environmental Toxicology: An International Journal 21 (1), 55-64, 2006 | 81 | 2006 |
| Comparative analysis of the cytotoxic effects of okadaic acid-group toxins on human intestinal cell lines PJ Ferron, K Hogeveen, V Fessard, L Le Hégarat Marine drugs 12 (8), 4616-4634, 2014 | 65 | 2014 |
| Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection E Bazin, S Huet, G Jarry, LL Hégarat, JS Munday, AR Humpage, ... Environmental toxicology 27 (5), 277-284, 2012 | 64 | 2012 |
| In vivo toxicity and genotoxicity of beauvericin and enniatins. Combined approach to study in vivo toxicity and genotoxicity of mycotoxins beauvericin (BEA) and … F Maranghi, R Tassinari, L Narciso, S Tait, CL Rocca, GD Felice, ... EFSA Supporting Publications 15 (5), 1406E, 2018 | 60 | 2018 |
| Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells J Dumont, R Jossé, C Lambert, S Anthérieu, L Le Hegarat, C Aninat, ... Toxicology and applied pharmacology 245 (2), 256-263, 2010 | 60 | 2010 |
| Performance of Comet and Micronucleus Assays in Metabolic Competent HepaRG Cells to Predict In Vivo Genotoxicity LL Hégarat, A Mourot, S Huet, L Vasseur, S Camus, C Chesné, V Fessard Toxicological sciences 138 (2), 300-309, 2014 | 58 | 2014 |
| The PERICLES research program: an integrated approach to characterize the combined effects of mixtures of pesticide residues to which the French population is exposed A Crépet, F Héraud, C Béchaux, ME Gouze, S Pierlot, A Fastier, ... Toxicology 313 (2-3), 83-93, 2013 | 58 | 2013 |
| Aneugenic potential of okadaic acid revealed by the micronucleus assay combined with the FISH technique in CHO-K1 cells L Le Hegarat, L Puech, V Fessard, JM Poul, S Dragacci Mutagenesis 18 (3), 293-298, 2003 | 53 | 2003 |
| Genotoxicity of aluminum and aluminum oxide nanomaterials in rats following oral exposure P Jalili, S Huet, R Lanceleur, G Jarry, LL Hegarat, F Nesslany, ... Nanomaterials 10 (2), 305, 2020 | 44 | 2020 |
| Modulation of CYP3A4 activity alters the cytotoxicity of lipophilic phycotoxins in human hepatic HepaRG cells PJ Ferron, K Hogeveen, G De Sousa, R Rahmani, E Dubreil, V Fessard, ... Toxicology in Vitro 33, 136-146, 2016 | 41 | 2016 |
| Marine toxin okadaic acid induces aneuploidy in CHO‐K1 cells in presence of rat liver postmitochondrial fraction, revealed by cytokinesis‐block micronucleus assay coupled to FISH L Le Hégarat, V Fessard, JM Poul, S Dragacci, P Sanders Environmental Toxicology: An International Journal 19 (2), 123-128, 2004 | 40 | 2004 |
| In vitro combined cytotoxic effects of pesticide cocktails simultaneously found in the French diet N Takakura, P Sanders, V Fessard, L Le Hégarat Food and chemical toxicology 52, 153-162, 2013 | 35 | 2013 |
| Combined effects of lipophilic phycotoxins (okadaic acid, azapsiracid-1 and yessotoxin) on human intestinal cells models PJ Ferron, K Dumazeau, JF Beaulieu, L Le Hégarat, V Fessard Toxins 8 (2), 50, 2016 | 31 | 2016 |
| Mixtures of lipophilic phycotoxins: exposure data and toxicological assessment J Alarcan, R Biré, L Le Hégarat, V Fessard Marine drugs 16 (2), 46, 2018 | 29 | 2018 |
