The role of the helper lipid on the DNA transfection efficiency of lipopolyplex formulations Z Du, MM Munye, AD Tagalakis, MDI Manunta, SL Hart Scientific reports 4 (1), 1-6, 2014 | 205 | 2014 |
Cell-derived apolipoprotein E (ApoE) particles inhibit vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells AK Stannard, DR Riddell, SM Sacre, AD Tagalakis, C Langer, ... Journal of Biological Chemistry 276 (49), 46011-46016, 2001 | 132 | 2001 |
Receptor-targeted liposome-peptide nanocomplexes for siRNA delivery AD Tagalakis, L He, L Saraiva, KT Gustafsson, SL Hart Biomaterials 32 (26), 6302-6315, 2011 | 106 | 2011 |
Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty AD Tagalakis, IR Graham, DR Riddell, JG Dickson, JS Owen Journal of Biological Chemistry 276 (16), 13226-13230, 2001 | 106 | 2001 |
Minicircle DNA provides enhanced and prolonged transgene expression following airway gene transfer MM Munye, AD Tagalakis, JL Barnes, RE Brown, RJ McAnulty, SJ Howe, ... Scientific reports 6 (1), 23125, 2016 | 86 | 2016 |
Multifunctional, self-assembling anionic peptide-lipid nanocomplexes for targeted siRNA delivery AD Tagalakis, DL Do Hyang, AS Bienemann, H Zhou, MM Munye, ... Biomaterials 35 (29), 8406-8415, 2014 | 84 | 2014 |
A receptor-targeted nanocomplex vector system optimized for respiratory gene transfer AD Tagalakis, RJ McAnulty, J Devaney, SE Bottoms, JB Wong, M Elbs, ... Molecular Therapy 16 (5), 907-915, 2008 | 73 | 2008 |
Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung AD Tagalakis, MM Munye, R Ivanova, H Chen, CM Smith, AM Aldossary, ... Thorax 73 (9), 847-856, 2018 | 69 | 2018 |
Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis MDI Manunta, AD Tagalakis, M Attwood, AM Aldossary, JL Barnes, ... Scientific reports 7 (1), 700, 2017 | 66 | 2017 |
Multifunctional receptor-targeted nanocomplexes for the delivery of therapeutic nucleic acids to the brain GD Kenny, AS Bienemann, AD Tagalakis, JA Pugh, K Welser, F Campbell, ... Biomaterials 34 (36), 9190-9200, 2013 | 65 | 2013 |
Receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient delivery system for MRTF silencing in conjunctival fibrosis C Yu-Wai-Man, AD Tagalakis, MD Manunta, SL Hart, PT Khaw Scientific reports 6 (1), 21881, 2016 | 64 | 2016 |
Tumor‐specific gene transfer with receptor‐mediated nanocomplexes modified by polyethylene glycol shielding and endosomally cleavable lipid and peptide linkers SM Grosse, AD Tagalakis, MFM Mustapa, M Elbs, QH Meng, ... The FASEB Journal 24 (7), 2301-2313, 2010 | 63 | 2010 |
Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium MDI Manunta, RJ McAnulty, AD Tagalakis, SE Bottoms, F Campbell, ... PloS one 6 (10), e26768, 2011 | 59 | 2011 |
Integrin-targeted nanocomplexes for tumour specific delivery and therapy by systemic administration AD Tagalakis, SM Grosse, QH Meng, MFM Mustapa, A Kwok, SE Salehi, ... Biomaterials 32 (5), 1370-1376, 2011 | 57 | 2011 |
Role of liposome and peptide in the synergistic enhancement of transfection with a lipopolyplex vector MM Munye, J Ravi, AD Tagalakis, D McCarthy, MG Ryadnov, SL Hart Scientific reports 5 (1), 9292, 2015 | 56 | 2015 |
PEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexes AD Tagalakis, GD Kenny, AS Bienemann, D McCarthy, MM Munye, ... Journal of Controlled Release 174, 177-187, 2014 | 56 | 2014 |
Intramuscular injection of a plasmid vector expressing human apolipoprotein E limits progression of xanthoma and aortic atheroma in apoE-deficient mice T Athanasopoulos, JS Owen, D Hassall, MG Dunckley, J Drew, ... Human Molecular Genetics 9 (17), 2545-2551, 2000 | 49 | 2000 |
Development of targeted siRNA nanocomplexes to prevent fibrosis in experimental glaucoma filtration surgery O Fernando, AD Tagalakis, S Awwad, S Brocchini, PT Khaw, SL Hart, ... Molecular Therapy 26 (12), 2812-2822, 2018 | 43 | 2018 |
3D printing in Ophthalmology: From medical implants to personalised medicine G Tan, N Ioannou, E Mathew, AD Tagalakis, DA Lamprou, C Yu-Wai-Man International Journal of Pharmaceutics 625, 122094, 2022 | 37 | 2022 |
Improved intracellular delivery of peptide-and lipid-nanoplexes by natural glycosides A Weng, MDI Manunta, M Thakur, R Gilabert-Oriol, AD Tagalakis, ... Journal of Controlled Release 206, 75-90, 2015 | 36 | 2015 |