| Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease C Janus, J Pearson, JA McLaurin, PM Mathews, Y Jiang, SD Schmidt, ... Nature 408 (6815), 979-982, 2000 | 2033 | 2000 |
| α-Synuclein membrane interactions and lipid specificity E Jo, JA McLaurin, CM Yip, PS George-Hyslop, PE Fraser Journal of Biological Chemistry 275 (44), 34328-34334, 2000 | 757 | 2000 |
| Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis J McLaurin, R Cecal, ME Kierstead, X Tian, AL Phinney, M Manea, ... Nature medicine 8 (11), 1263-1269, 2002 | 570 | 2002 |
| Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model JA McLaurin, ME Kierstead, ME Brown, CA Hawkes, MHL Lambermon, ... Nature medicine 12 (7), 801-808, 2006 | 455 | 2006 |
| Membrane disruption by Alzheimer β-amyloid peptides mediated through specific binding to either phospholipids or gangliosides: implications for neurotoxicity JA McLaurin, A Chakrabartty Journal of Biological Chemistry 271 (43), 26482-26489, 1996 | 433 | 1996 |
| Antibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-β plaque load in the TgCRND8 mouse model of Alzheimer's disease JF Jordão, CA Ayala-Grosso, K Markham, Y Huang, R Chopra, ... PloS one 5 (5), e10549, 2010 | 428 | 2010 |
| Selective targeting of perivascular macrophages for clearance of β-amyloid in cerebral amyloid angiopathy CA Hawkes, JA McLaurin Proceedings of the National Academy of Sciences 106 (4), 1261-1266, 2009 | 413 | 2009 |
| Inositol stereoisomers stabilize an oligomeric aggregate of Alzheimer amyloid β peptide and inhibit Aβ-induced toxicity JA McLaurin, R Golomb, A Jurewicz, JP Antel, PE Fraser Journal of Biological Chemistry 275 (24), 18495-18502, 2000 | 375 | 2000 |
| Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound JF Jordão, E Thévenot, K Markham-Coultes, T Scarcelli, YQ Weng, ... Experimental neurology 248, 16-29, 2013 | 344 | 2013 |
| Modulating factors in amyloid-β fibril formation J McLaurin, DS Yang, CM Yip, PE Fraser Journal of Structural Biology 130 (2-3), 259-270, 2000 | 340 | 2000 |
| Interactions of Alzheimer amyloid‐β peptides with glycosaminoglycans: Effects on fibril nucleation and growth JA McLaurin, T Franklin, X Zhang, J Deng, PE Fraser European journal of biochemistry 266 (3), 1101-1110, 1999 | 323 | 1999 |
| Amyloid-β peptide assembly: a critical step in fibrillogenesis and membrane disruption CM Yip, JA McLaurin Biophysical journal 80 (3), 1359-1371, 2001 | 289 | 2001 |
| Characterization of the interactions of Alzheimer β‐amyloid peptides with phospholipid membranes JA McLaurin, A Chakrabartty European Journal of Biochemistry 245 (2), 355-363, 1997 | 260 | 1997 |
| Immunotherapy for Alzheimer's disease DS Gelinas, K DaSilva, D Fenili, P St. George-Hyslop, JA McLaurin Proceedings of the National Academy of Sciences 101 (suppl_2), 14657-14662, 2004 | 251 | 2004 |
| CD163 identifies perivascular macrophages in normal and viral encephalitic brains and potential precursors to perivascular macrophages in blood WK Kim, X Alvarez, J Fisher, B Bronfin, S Westmoreland, JA McLaurin, ... The American journal of pathology 168 (3), 822-834, 2006 | 249 | 2006 |
| Cholesterol, a modulator of membrane-associated Aβ-fibrillogenesis and neurotoxicity CM Yip, EA Elton, AA Darabie, MR Morrison, J McLaurin Journal of molecular biology 311 (4), 723-734, 2001 | 248 | 2001 |
| Structural transitions associated with the interaction of Alzheimer β-amyloid peptides with gangliosides JA McLaurin, T Franklin, PE Fraser, A Chakrabartty Journal of Biological Chemistry 273 (8), 4506-4515, 1998 | 225 | 1998 |
| Aβ42-peptide assembly on lipid bilayers CM Yip, AA Darabie, JA McLaurin Journal of molecular biology 318 (1), 97-107, 2002 | 224 | 2002 |
| Phosphatidylinositol and inositol involvement in Alzheimer amyloid-β fibril growth and arrest J McLaurin, T Franklin, A Chakrabartty, PE Fraser Journal of molecular biology 278 (1), 183-194, 1998 | 195 | 1998 |
| Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease A Dorr, B Sahota, LV Chinta, ME Brown, AY Lai, K Ma, CA Hawkes, ... Brain 135 (10), 3039-3050, 2012 | 187 | 2012 |
