Infection of bat and human intestinal organoids by SARS-CoV-2 J Zhou, C Li, X Liu, MC Chiu, X Zhao, D Wang, Y Wei, A Lee, AJ Zhang, ... Nature medicine 26 (7), 1077-1083, 2020 | 543 | 2020 |
Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus J Zhou, C Li, G Zhao, H Chu, D Wang, HHN Yan, VKM Poon, L Wen, ... Science advances 3 (11), eaao4966, 2017 | 436 | 2017 |
Differentiated human airway organoids to assess infectivity of emerging influenza virus J Zhou, C Li, N Sachs, MC Chiu, BHY Wong, H Chu, VKM Poon, D Wang, ... Proceedings of the National Academy of Sciences 115 (26), 6822-6827, 2018 | 260 | 2018 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 235 | 2019 |
Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells H Chu, CM Chan, X Zhang, Y Wang, S Yuan, J Zhou, RKH Au-Yeung, ... Journal of Biological Chemistry 293 (30), 11709-11726, 2018 | 181 | 2018 |
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses Y Chen, X Zhao, H Zhou, H Zhu, S Jiang, P Wang Nature Reviews Immunology 23 (3), 189-199, 2023 | 174 | 2023 |
Antibody evasion of SARS-CoV-2 Omicron BA. 1, BA. 1.1, BA. 2, and BA. 3 sub-lineages J Ai, X Wang, X He, X Zhao, Y Zhang, Y Jiang, M Li, Y Cui, Y Chen, ... Cell host & microbe 30 (8), 1077-1083. e4, 2022 | 149 | 2022 |
Homologous or heterologous booster of inactivated vaccine reduces SARS-CoV-2 Omicron variant escape from neutralizing antibodies X Wang, X Zhao, J Song, J Wu, Y Zhu, M Li, Y Cui, Y Chen, L Yang, J Liu, ... Emerging microbes & infections 11 (1), 477-481, 2022 | 139 | 2022 |
Carcinoembryonic antigen-related cell adhesion molecule 5 is an important surface attachment factor that facilitates entry of Middle East respiratory syndrome coronavirus CM Chan, H Chu, Y Wang, BHY Wong, X Zhao, J Zhou, D Yang, ... Journal of virology 90 (20), 9114-9127, 2016 | 88 | 2016 |
Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severity H Chu, H Shuai, Y Hou, X Zhang, L Wen, X Huang, B Hu, D Yang, ... Science advances 7 (25), eabf8577, 2021 | 65 | 2021 |
Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza H Zhao, KKW To, H Chu, Q Ding, X Zhao, C Li, H Shuai, S Yuan, J Zhou, ... Nature communications 9 (1), 2358, 2018 | 57 | 2018 |
Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target C Li, H Chu, X Liu, MC Chiu, X Zhao, D Wang, Y Wei, Y Hou, H Shuai, ... Emerging Microbes & Infections 9 (1), 2663-2672, 2020 | 55 | 2020 |
Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target S Yuan, H Chu, J Huang, X Zhao, ZW Ye, PM Lai, L Wen, JP Cai, Y Mo, ... Science advances 6 (35), eaba7910, 2020 | 54 | 2020 |
Coronaviruses exploit a host cysteine-aspartic protease for replication H Chu, Y Hou, D Yang, L Wen, H Shuai, C Yoon, J Shi, Y Chai, TTT Yuen, ... Nature 609 (7928), 785-792, 2022 | 51 | 2022 |
Human intestinal organoids recapitulate enteric infections of enterovirus and coronavirus X Zhao, C Li, X Liu, MC Chiu, D Wang, Y Wei, H Chu, JP Cai, IHY Chan, ... Stem Cell Reports 16 (3), 493-504, 2021 | 51 | 2021 |
Activation of C-type lectin receptor and (RIG)-I-like receptors contributes to proinflammatory response in Middle East respiratory syndrome coronavirus-infected macrophages X Zhao, H Chu, BHY Wong, MC Chiu, D Wang, C Li, X Liu, D Yang, ... The Journal of infectious diseases 221 (4), 647-659, 2020 | 49 | 2020 |
Identification and characterization of GLDC as host susceptibility gene to severe influenza J Zhou, D Wang, BHY Wong, C Li, VKM Poon, L Wen, X Zhao, MC Chiu, ... EMBO molecular medicine 11 (1), e9528, 2019 | 21 | 2019 |
Neutralization of Omicron BA. 4/BA. 5 and BA. 2.75 by booster vaccination or BA. 2 breakthrough infection sera X Wang, J Ai, X Li, X Zhao, J Wu, H Zhang, X He, C Zhao, R Qiao, M Li, ... Cell Discovery 8 (1), 110, 2022 | 19 | 2022 |
Biochemical characterization of NADP+-dependent isocitrate dehydrogenase from Microcystis aeruginosa PCC7806 MM Jin, P Wang, X Li, XY Zhao, L Xu, P Song, GP Zhu Molecular biology reports 40, 2995-3002, 2013 | 17 | 2013 |
Development of three-dimensional human intestinal organoids as a physiologically relevant model for characterizing the viral replication kinetics and antiviral susceptibility … JOL Tsang, J Zhou, X Zhao, C Li, Z Zou, F Yin, S Yuan, ML Yeung, H Chu, ... Biomedicines 9 (1), 88, 2021 | 16 | 2021 |