A method for the acute and rapid degradation of endogenous proteins D Clift, WA McEwan, LI Labzin, V Konieczny, B Mogessie, LC James, ... Cell 171 (7), 1692-1706. e18, 2017 | 442 | 2017 |
Restarting life: fertilization and the transition from meiosis to mitosis D Clift, M Schuh Nature reviews Molecular cell biology 14 (9), 549-562, 2013 | 360 | 2013 |
Anti-commensal IgG drives intestinal inflammation and type 17 immunity in ulcerative colitis T Castro-Dopico, TW Dennison, JR Ferdinand, RJ Mathews, A Fleming, ... Immunity 50 (4), 1099-1114. e10, 2019 | 189 | 2019 |
A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes D Clift, M Schuh Nature communications 6 (1), 7217, 2015 | 169 | 2015 |
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation WA McEwan, B Falcon, M Vaysburd, D Clift, AL Oblak, B Ghetti, ... Proceedings of the National Academy of Sciences 114 (3), 574-579, 2017 | 167 | 2017 |
A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes C So, KB Seres, AM Steyer, E Mönnich, D Clift, A Pejkovska, W Möbius, ... Science 364 (6447), eaat9557, 2019 | 149 | 2019 |
Acute and rapid degradation of endogenous proteins by Trim-Away D Clift, C So, WA McEwan, LC James, M Schuh Nature Protocols 13 (10), 2149-2175, 2018 | 138 | 2018 |
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome G Balmus, D Larrieu, AC Barros, C Collins, M Abrudan, M Demir, ... Nature communications 9 (1), 1700, 2018 | 131 | 2018 |
Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere KF Verzijlbergen, OO Nerusheva, D Kelly, A Kerr, D Clift, F de Lima Alves, ... Elife 3, e01374, 2014 | 99 | 2014 |
Shugoshin prevents cohesin cleavage by PP2ACdc55-dependent inhibition of separase D Clift, F Bizzari, AL Marston Genes & development 23 (6), 766-780, 2009 | 78 | 2009 |
The role of shugoshin in meiotic chromosome segregation D Clift, AL Marston Cytogenetic and genome research 133 (2-4), 234-242, 2011 | 76 | 2011 |
Complement C4 prevents viral infection through capsid inactivation M Bottermann, S Foss, SL Caddy, D Clift, LM van Tienen, M Vaysburd, ... Cell host & microbe 25 (4), 617-629. e7, 2019 | 58 | 2019 |
Target-induced clustering activates Trim-Away of pathogens and proteins J Zeng, AF Santos, AS Mukadam, M Osswald, DA Jacques, CF Dickson, ... Nature structural & molecular biology 28 (3), 278-289, 2021 | 56 | 2021 |
RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination L Kiss, D Clift, N Renner, D Neuhaus, LC James Nature Communications 12 (1), 1220, 2021 | 40 | 2021 |
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection LI Labzin, M Bottermann, P Rodriguez‐Silvestre, S Foss, JT Andersen, ... The EMBO Journal 38 (21), e101365, 2019 | 39 | 2019 |
A functional assay for serum detection of antibodies against SARS‐CoV‐2 nucleoprotein A Albecka, D Clift, M Vaysburd, T Rhinesmith, SL Caddy, DM Favara, ... The EMBO journal 40 (17), e108588, 2021 | 19 | 2021 |
SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase XB Su, M Wang, C Schaffner, OO Nerusheva, D Clift, C Spanos, DA Kelly, ... Journal of Cell Biology 220 (7), e202005130, 2021 | 13 | 2021 |
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates L Kiss, T Rhinesmith, J Luptak, CF Dickson, J Weidenhausen, S Smyly, ... Nature Communications 14 (1), 2160, 2023 | 7 | 2023 |
TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminal glutamine generated by 3C protease processing J Luptak, DL Mallery, AS Jahun, A Albecka, D Clift, O Ather, G Slodkowicz, ... Viruses 14 (8), 1610, 2022 | 7 | 2022 |
A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation A Fletcher, D Clift, E de Vries, S Martinez Cuesta, T Malcolm, F Meghini, ... Nature Communications 14 (1), 7093, 2023 | 6 | 2023 |