DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 593 (7860), 586-590, 2021 | 998 | 2021 |
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis X Liu, L Nie, Y Zhang, Y Yan, C Wang, M Colic, K Olszewski, A Horbath, ... Nature cell biology 25 (3), 404-414, 2023 | 399 | 2023 |
Ferroptosis, radiotherapy, and combination therapeutic strategies G Lei, C Mao, Y Yan, L Zhuang, B Gan Protein & cell 12 (11), 836-857, 2021 | 235 | 2021 |
A targetable CoQ-FSP1 axis drives ferroptosis-and radiation-resistance in KEAP1 inactive lung cancers P Koppula, G Lei, Y Zhang, Y Yan, C Mao, L Kondiparthi, J Shi, X Liu, ... Nature communications 13 (1), 2206, 2022 | 204 | 2022 |
Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity G Lei, Y Zhang, T Hong, X Zhang, X Liu, C Mao, Y Yan, P Koppula, ... Oncogene 40 (20), 3533-3547, 2021 | 129 | 2021 |
DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program YL Yan, C Zhang, J Hao, XL Wang, J Ming, L Mi, J Na, X Hu, Y Wang PLoS biology 17 (6), e3000324, 2019 | 85 | 2019 |
SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells Y Yan, H Teng, Q Hang, L Kondiparthi, G Lei, A Horbath, X Liu, C Mao, ... Nature communications 14 (1), 3673, 2023 | 59 | 2023 |
Suppression of epithelial–mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells WT Guo, XW Wang, YL Yan, YP Li, X Yin, Q Zhang, C Melton, A Shenoy, ... Cell Death & Differentiation 22 (7), 1158-1169, 2015 | 44 | 2015 |
Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 596 (7873), E13-E13, 2021 | 17 | 2021 |
Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition C Mao, X Liu, Y Yan, K Olszewski, B Gan Nature 619 (7968), E19-E23, 2023 | 10 | 2023 |
Cellular redox state as a critical factor in initiating early embryonic-like program in embryonic stem cells C Zhang, YL Yan, J Hao, Y Wang Cell discovery 5 (1), 59, 2019 | 8 | 2019 |
A mTORC1-mediated cyst (e) ine sensing mechanism governing GPX4 synthesis and ferroptosis Y Yan, G Lei, B Gan Molecular & Cellular Oncology 8 (3), 1919006, 2021 | 4 | 2021 |
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer., 2021, 593 C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... DOI: https://doi. org/10.1038/s41586-021-03539-7, 586-590, 2021 | 4 | 2021 |
BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers G Lei, C Mao, AD Horbath, Y Yan, S Cai, J Yao, Y Jiang, M Sun, X Liu, ... Cancer Discovery, OF1-OF20, 2024 | 2 | 2024 |
Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers C Mao, G Lei, A Horbath, M Wang, Z Lu, Y Yan, X Liu, L Kondiparthi, ... Molecular Cell 84 (10), 1964-1979. e6, 2024 | 1 | 2024 |
IRE1α determines ferroptosis sensitivity through regulation of glutathione synthesis D Jiang, Y Guo, T Wang, L Wang, Y Yan, L Xia, R Bam, Z Yang, H Lee, ... Nature communications 15 (1), 4114, 2024 | 1 | 2024 |
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer (vol 593, pg 586, 2021) C Mao, X Liu, Y Zhang, G Lei, Y Yan, H Lee, P Koppula, S Wu, L Zhuang, ... Nature 596 (7873), E13-E13, 2021 | 1 | 2021 |
Dodging death Y Yan, B Gan Nature Chemical Biology, 1-2, 2024 | | 2024 |
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis X Liu, Z Chen, Y Yan, F Zandkarimi, L Nie, Q Li, A Horbath, K Olszewski, ... Protein & Cell, pwae004, 2024 | | 2024 |
Hyperoxidized PRDX3 as a specific ferroptosis marker Y Yan, B Gan Life metabolism 2 (6), load042, 2023 | | 2023 |