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Brian O'Callaghan Diekman
Brian O'Callaghan Diekman
Assistant Professor of Biomedical Engineering, UNC/NC State Joint Department
在 email.unc.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Ageing and the pathogenesis of osteoarthritis
RF Loeser, JA Collins, BO Diekman
Nature Reviews Rheumatology 12 (7), 412-420, 2016
10532016
Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype
BT Estes, BO Diekman, JM Gimble, F Guilak
Nature protocols 5 (7), 1294-1311, 2010
5222010
Mechanisms and therapeutic implications of cellular senescence in osteoarthritis
PR Coryell, BO Diekman, RF Loeser
Nature Reviews Rheumatology 17 (1), 47-57, 2021
4012021
Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix
BO Diekman, CR Rowland, DP Lennon, AI Caplan, F Guilak
Tissue Engineering Part A 16 (2), 523-533, 2010
3392010
Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells
BO Diekman, N Christoforou, VP Willard, H Sun, J Sanchez-Adams, ...
Proceedings of the National Academy of Sciences 109 (47), 19172-19177, 2012
3042012
Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence
JY Liu, GP Souroullas, BO Diekman, J Krishnamurthy, BM Hall, ...
Proceedings of the National Academy of Sciences 116 (7), 2603-2611, 2019
2712019
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice
EJ Novais, VA Tran, SN Johnston, KR Darris, AJ Roupas, GA Sessions, ...
Nature Communications 12 (1), 5213, 2021
2042021
2010 Nicolas Andry Award: multipotent adult stem cells from adipose tissue for musculoskeletal tissue engineering
F Guilak, BT Estes, BO Diekman, FT Moutos, JM Gimble
Clinical Orthopaedics and Related Research® 468 (9), 2530-2540, 2010
1942010
Stem cell-based therapies for osteoarthritis: challenges and opportunities
BO Diekman, F Guilak
Current opinion in rheumatology 25 (1), 119-126, 2013
1802013
Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis
BO Diekman, CL Wu, CR Louer, BD Furman, JL Huebner, VB Kraus, ...
Cell transplantation 22 (8), 1395-1408, 2013
1612013
In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly (ɛ-caprolactone) scaffolds
PK Valonen, FT Moutos, A Kusanagi, MG Moretti, BO Diekman, JF Welter, ...
Biomaterials 31 (8), 2193-2200, 2010
1392010
Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis
BO Diekman, GA Sessions, JA Collins, AK Knecht, SL Strum, NK Mitin, ...
Aging cell 17 (4), e12771, 2018
1332018
Targeting aging for disease modification in osteoarthritis
JA Collins, BO Diekman, RF Loeser
Current opinion in rheumatology 30 (1), 101-107, 2018
1222018
Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids
CL Wu, BO Diekman, D Jain, F Guilak
International journal of obesity 37 (8), 1079-1087, 2013
1222013
Monolayer cell expansion conditions affect the chondrogenic potential of adipose‐derived stem cells
BT Estes, BO Diekman, F Guilak
Biotechnology and bioengineering 99 (4), 986-995, 2008
902008
p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence
EJ Novais, BO Diekman, IM Shapiro, MV Risbud
Matrix Biology 82, 54-70, 2019
852019
The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors
BO Diekman, BT Estes, F Guilak
Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2010
832010
Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening
VP Willard, BO Diekman, J Sanchez‐Adams, N Christoforou, KW Leong, ...
Arthritis & Rheumatology 66 (11), 3062-3072, 2014
542014
Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture
GA Sessions, ME Copp, JY Liu, MA Sinkler, S D’Costa, BO Diekman
The FASEB Journal 33 (11), 12364, 2019
422019
Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes
JA Collins, M Kapustina, JA Bolduc, JFW Pike, BO Diekman, K Mix, ...
Free Radical Biology and Medicine 166, 90-103, 2021
332021
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