Ageing and the pathogenesis of osteoarthritis RF Loeser, JA Collins, BO Diekman Nature Reviews Rheumatology 12 (7), 412-420, 2016 | 1053 | 2016 |
Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype BT Estes, BO Diekman, JM Gimble, F Guilak Nature protocols 5 (7), 1294-1311, 2010 | 522 | 2010 |
Mechanisms and therapeutic implications of cellular senescence in osteoarthritis PR Coryell, BO Diekman, RF Loeser Nature Reviews Rheumatology 17 (1), 47-57, 2021 | 401 | 2021 |
Chondrogenesis of adult stem cells from adipose tissue and bone marrow: induction by growth factors and cartilage-derived matrix BO Diekman, CR Rowland, DP Lennon, AI Caplan, F Guilak Tissue Engineering Part A 16 (2), 523-533, 2010 | 339 | 2010 |
Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells BO Diekman, N Christoforou, VP Willard, H Sun, J Sanchez-Adams, ... Proceedings of the National Academy of Sciences 109 (47), 19172-19177, 2012 | 304 | 2012 |
Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence JY Liu, GP Souroullas, BO Diekman, J Krishnamurthy, BM Hall, ... Proceedings of the National Academy of Sciences 116 (7), 2603-2611, 2019 | 271 | 2019 |
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice EJ Novais, VA Tran, SN Johnston, KR Darris, AJ Roupas, GA Sessions, ... Nature Communications 12 (1), 5213, 2021 | 204 | 2021 |
2010 Nicolas Andry Award: multipotent adult stem cells from adipose tissue for musculoskeletal tissue engineering F Guilak, BT Estes, BO Diekman, FT Moutos, JM Gimble Clinical Orthopaedics and Related Research® 468 (9), 2530-2540, 2010 | 194 | 2010 |
Stem cell-based therapies for osteoarthritis: challenges and opportunities BO Diekman, F Guilak Current opinion in rheumatology 25 (1), 119-126, 2013 | 180 | 2013 |
Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis BO Diekman, CL Wu, CR Louer, BD Furman, JL Huebner, VB Kraus, ... Cell transplantation 22 (8), 1395-1408, 2013 | 161 | 2013 |
In vitro generation of mechanically functional cartilage grafts based on adult human stem cells and 3D-woven poly (ɛ-caprolactone) scaffolds PK Valonen, FT Moutos, A Kusanagi, MG Moretti, BO Diekman, JF Welter, ... Biomaterials 31 (8), 2193-2200, 2010 | 139 | 2010 |
Expression of p16INK4a is a biomarker of chondrocyte aging but does not cause osteoarthritis BO Diekman, GA Sessions, JA Collins, AK Knecht, SL Strum, NK Mitin, ... Aging cell 17 (4), e12771, 2018 | 133 | 2018 |
Targeting aging for disease modification in osteoarthritis JA Collins, BO Diekman, RF Loeser Current opinion in rheumatology 30 (1), 101-107, 2018 | 122 | 2018 |
Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids CL Wu, BO Diekman, D Jain, F Guilak International journal of obesity 37 (8), 1079-1087, 2013 | 122 | 2013 |
Monolayer cell expansion conditions affect the chondrogenic potential of adipose‐derived stem cells BT Estes, BO Diekman, F Guilak Biotechnology and bioengineering 99 (4), 986-995, 2008 | 90 | 2008 |
p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence EJ Novais, BO Diekman, IM Shapiro, MV Risbud Matrix Biology 82, 54-70, 2019 | 85 | 2019 |
The effects of BMP6 overexpression on adipose stem cell chondrogenesis: Interactions with dexamethasone and exogenous growth factors BO Diekman, BT Estes, F Guilak Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2010 | 83 | 2010 |
Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening VP Willard, BO Diekman, J Sanchez‐Adams, N Christoforou, KW Leong, ... Arthritis & Rheumatology 66 (11), 3062-3072, 2014 | 54 | 2014 |
Controlled induction and targeted elimination of p16INK4a-expressing chondrocytes in cartilage explant culture GA Sessions, ME Copp, JY Liu, MA Sinkler, S D’Costa, BO Diekman The FASEB Journal 33 (11), 12364, 2019 | 42 | 2019 |
Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes JA Collins, M Kapustina, JA Bolduc, JFW Pike, BO Diekman, K Mix, ... Free Radical Biology and Medicine 166, 90-103, 2021 | 33 | 2021 |