| Specific killing of BRCA2-deficient tumours with inhibitors of poly (ADP-ribose) polymerase HE Bryant, N Schultz, HD Thomas, KM Parker, D Flower, E Lopez, S Kyle, ... Nature 434 (7035), 913-917, 2005 | 5782 | 2005 |
| Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair E Petermann, ML Orta, N Issaeva, N Schultz, T Helleday Molecular cell 37 (4), 492-502, 2010 | 922 | 2010 |
| PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination HE Bryant, E Petermann, N Schultz, AS Jemth, O Loseva, N Issaeva, ... The EMBO journal 28 (17), 2601-2615, 2009 | 733 | 2009 |
| MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool H Gad, T Koolmeister, AS Jemth, S Eshtad, SA Jacques, CE Ström, ... Nature 508 (7495), 215-221, 2014 | 564 | 2014 |
| Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity E Berglund, J Maaskola, N Schultz, S Friedrich, M Marklund, ... Nature communications 9 (1), 2419, 2018 | 482 | 2018 |
| Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks N Saleh-Gohari, HE Bryant, N Schultz, KM Parker, TN Cassel, T Helleday Molecular and cellular biology, 2005 | 424 | 2005 |
| Poly (ADP‐ribose) polymerase (PARP‐1) has a controlling role in homologous recombination N Schultz, E Lopez, N Saleh‐Gohari, T Helleday Nucleic acids research 31 (17), 4959-4964, 2003 | 404 | 2003 |
| Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells C Lundin, K Erixon, C Arnaudeau, N Schultz, D Jenssen, M Meuth, ... Molecular and cellular biology, 2002 | 311 | 2002 |
| Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer M Asim, F Tarish, HI Zecchini, K Sanjiv, E Gelali, CE Massie, A Baridi, ... Nature communications 8 (1), 374, 2017 | 281 | 2017 |
| Poly (ADP-Ribose) polymerase is hyperactivated in homologous recombination–defective cells P Gottipati, B Vischioni, N Schultz, J Solomons, HE Bryant, T Djureinovic, ... Cancer research 70 (13), 5389-5398, 2010 | 273 | 2010 |
| Poly (ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy T Helleday, HE Bryant, N Schultz Cell cycle 4 (9), 1176-1178, 2005 | 243 | 2005 |
| Kinetics and dose-response of residual 53BP1/γ-H2AX foci: Co-localization, relationship with DSB repair and clonogenic survival E Markova, N Schultz, IY Belyaev International journal of radiation biology 83 (5), 319-329, 2007 | 223 | 2007 |
| Spatially resolved clonal copy number alterations in benign and malignant tissue A Erickson, M He, E Berglund, M Marklund, R Mirzazadeh, N Schultz, ... Nature 608 (7922), 360-367, 2022 | 164 | 2022 |
| Cancer-specific synthetic lethality between ATR and CHK1 kinase activities K Sanjiv, A Hagenkort, JM Calderón-Montaño, T Koolmeister, PM Reaper, ... Cell reports 14 (2), 298-309, 2016 | 156 | 2016 |
| RAD51 is involved in repair of damage associated with DNA replication in mammalian cells C Lundin, N Schultz, C Arnaudeau, A Mohindra, LT Hansen, T Helleday Journal of molecular biology 328 (3), 521-535, 2003 | 146 | 2003 |
| Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro P Mellroth, J Karlsson, J Håkansson, N Schultz, WE Goldman, H Steiner Proceedings of the National Academy of Sciences 102 (18), 6455-6460, 2005 | 133 | 2005 |
| The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links AZ Al-Minawi, YF Lee, D Håkansson, F Johansson, C Lundin, ... Nucleic acids research 37 (19), 6400-6413, 2009 | 123 | 2009 |
| Castration radiosensitizes prostate cancer tissue by impairing DNA double-strand break repair FL Tarish, N Schultz, A Tanoglidi, H Hamberg, H Letocha, K Karaszi, ... Science translational medicine 7 (312), 312re11-312re11, 2015 | 110 | 2015 |
| The detection and evaluation of aneugenic chemicals JM Parry, EM Parry, R Boumer, A Doherty, S Ellard, J O'Donovan, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 353 (1 …, 1996 | 94 | 1996 |
| Methylated DNA causes a physical block to replication forks independently of damage signalling, O6-methylguanine or DNA single-strand breaks and results in DNA damage P Groth, S Ausländer, MM Majumder, N Schultz, F Johansson, ... Journal of molecular biology 402 (1), 70-82, 2010 | 93 | 2010 |
