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Kellen Chen
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Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring
S Mascharak, HE DesJardins-Park, MF Davitt, M Griffin, MR Borrelli, ...
Science 372 (6540), eaba2374, 2021
3292021
Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing
Y Jiang, AA Trotsyuk, S Niu, D Henn, K Chen, CC Shih, MR Larson, ...
Nature biotechnology 41 (5), 652-662, 2023
1522023
Role of boundary conditions in determining cell alignment in response to stretch
K Chen, A Vigliotti, M Bacca, RM McMeeking, VS Deshpande, JW Holmes
Proceedings of the National Academy of Sciences 115 (5), 986-991, 2018
1122018
Integrated spatial multiomics reveals fibroblast fate during tissue repair
DS Foster, M Januszyk, KE Yost, MS Chinta, GS Gulati, AT Nguyen, ...
Proceedings of the National Academy of Sciences 118 (41), e2110025118, 2021
1052021
Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
S Mascharak*, HE Talbott*, M Januszyk*, M Griffin**, K Chen**, MF Davitt, ...
Cell Stem Cell, 2022
932022
Hydrogel Scaffolds to Deliver Cell Therapies for Wound Healing
D Sivaraj*, K Chen*, A Chattopadhyay, D Henn, W Wu, C Noishiki, ...
Frontiers in Bioengineering and Biotechnology 9, 337, 2021
842021
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin
DS Foster, M Januszyk, D Delitto, KE Yost, M Griffin, J Guo, N Guardino, ...
Cancer Cell 40 (11), 1392-1406. e7, 2022
722022
Disrupting biological sensors of force promotes tissue regeneration in large organisms
K Chen, SH Kwon, D Henn, BA Kuehlmann, R Tevlin, CA Bonham, ...
Nature communications 12 (1), 5256, 2021
522021
Characterization of Diabetic and Non-Diabetic Foot Ulcers Using Single-Cell RNA-Sequencing
M Januszyk*, K Chen*, D Henn, DS Foster, MR Borrelli, CA Bonham, ...
Micromachines 11 (9), 815, 2020
462020
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models
MF Griffin, MR Borrelli, JT Garcia, M Januszyk, M King, T Lerbs, L Cui, ...
Science translational medicine 13 (609), eabb3312, 2021
452021
Adipose-derived stromal cells seeded in pullulan-collagen hydrogels improve healing in murine burns
J Barrera*, A Trotsyuk*, ZN Maan, CA Bonham, MR Larson, ...
Tissue Engineering, 2021
392021
Pullulan‐Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings
K Chen, D Sivaraj, MF Davitt, MC Leeolou, D Henn, SR Steele, ...
Wound Repair and Regeneration 30 (3), 397-408, 2022
382022
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting
K Chen, D Henn, M Januszyk, JA Barrera, C Noishiki, CA Bonham, ...
Science Translational Medicine 14 (645), eabj9152, 2022
352022
Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2+ macrophages
D Henn, K Chen, T Fehlmann, AA Trotsyuk, D Sivaraj, ZN Maan, ...
Science advances 7 (49), eabi4528, 2021
282021
Multiscale computational model of Achilles tendon wound healing: Untangling the effects of repair and loading
K Chen, X Hu, SS Blemker, JW Holmes
PLoS computational biology 14 (12), e1006652, 2018
242018
Macrophage subpopulation dynamics shift following intravenous infusion of mesenchymal stromal cells
N Kosaric, W Srifa, CA Bonham, H Kiwanuka, K Chen, BA Kuehlmann, ...
Molecular Therapy 28 (9), 2007-2022, 2020
222020
Mechanical strain drives myeloid cell differentiation toward proinflammatory subpopulations
K Chen, D Henn, D Sivaraj, CA Bonham, M Griffin, HC Kussie, ...
Advances in wound care 11 (9), 466-478, 2022
192022
A comparative analysis of deferoxamine treatment modalities for dermal radiation‐induced fibrosis
CV Lavin, DB Abbas, EJ Fahy, DK Lee, M Griffin, NM Diaz Deleon, ...
Journal of Cellular and Molecular Medicine 25 (21), 10028-10038, 2021
172021
Understanding scarring in the oral mucosa
MF Griffin, EJ Fahy, M King, N Guardino, K Chen, DB Abbas, CV Lavin, ...
Advances in wound care 11 (10), 537-547, 2022
162022
Cryopreserved human skin allografts promote angiogenesis and dermal regeneration in a murine model
D Henn, K Chen, ZN Maan, AH Greco, SE Moortgat Illouz, CA Bonham, ...
International Wound Journal 17 (4), 925-936, 2020
142020
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