关注
James Kaczmarek
James Kaczmarek
Associate Director at ReCode Therapeutics
在 recodetx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Advances in the delivery of RNA therapeutics: from concept to clinical reality
JC Kaczmarek, PS Kowalski, DG Anderson
Genome medicine 9, 1-16, 2017
6732017
Polymer–lipid nanoparticles for systemic delivery of mRNA to the lungs
JC Kaczmarek, AK Patel, KJ Kauffman, OS Fenton, MJ Webber, ...
Angewandte Chemie 128 (44), 14012-14016, 2016
3162016
Inhaled nanoformulated mRNA polyplexes for protein production in lung epithelium
AK Patel, JC Kaczmarek, S Bose, KJ Kauffman, F Mir, MW Heartlein, ...
Advanced Materials 31 (8), 1805116, 2019
3062019
Synthesis and biological evaluation of ionizable lipid materials for the in vivo delivery of messenger RNA to B lymphocytes
OS Fenton, KJ Kauffman, JC Kaczmarek, RL McClellan, S Jhunjhunwala, ...
Advanced Materials 29 (33), 1606944, 2017
2102017
Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells
JC Kaczmarek, KJ Kauffman, OS Fenton, K Sadtler, AK Patel, ...
Nano letters 18 (10), 6449-6454, 2018
1862018
Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
KJ Kauffman, FF Mir, S Jhunjhunwala, JC Kaczmarek, JE Hurtado, ...
Biomaterials 109, 78-87, 2016
1862016
Rapid, single-cell analysis and discovery of vectored mRNA transfection in vivo with a loxP-flanked tdTomato reporter mouse
KJ Kauffman, MA Oberli, JR Dorkin, JE Hurtado, JC Kaczmarek, ...
Molecular therapy-Nucleic acids 10, 55-63, 2018
842018
Customizable lipid nanoparticle materials for the delivery of siRNAs and mRNAs
OS Fenton, KJ Kauffman, RL McClellan, JC Kaczmarek, MD Zeng, ...
Angewandte Chemie International Edition 57 (41), 13582-13586, 2018
812018
Systemic delivery of mRNA and DNA to the lung using polymer-lipid nanoparticles
JC Kaczmarek, AK Patel, LH Rhym, UC Palmiero, B Bhat, MW Heartlein, ...
Biomaterials 275, 120966, 2021
732021
Poly(β‐amino ester)‐co‐poly(caprolactone) Terpolymers as Nonviral Vectors for mRNA Delivery In Vitro and In Vivo
U Capasso Palmiero, JC Kaczmarek, OS Fenton, DG Anderson
Advanced Healthcare Materials 7 (14), 1800249, 2018
722018
Cancer nanotherapeutics in clinical trials
AKR Lytton-Jean, KJ Kauffman, JC Kaczmarek, R Langer
Nanotechnology-Based Precision Tools for the Detection and Treatment of …, 2015
512015
Adjusting biomaterial composition to achieve controlled multiple-day release of dexamethasone from an extended-wear silicone hydrogel contact lens
JC Kaczmarek, A Tieppo, CJ White, ME Byrne
Journal of Biomaterials Science, Polymer Edition 25 (1), 88-100, 2014
422014
Poly (beta-amino esters) and uses thereof
DG Anderson, KJ Kauffman, JC Kaczmarek, AK Patel
US Patent 11,464,860, 2022
32022
Polymer-lipids and compositions
JC Kaczmarek, DG Anderson, LH Rhym, KJ Kauffman, AK Patel
US Patent 11,608,412, 2023
22023
Gene delivery carrier
UC Palmiero, JC Kaczmarek, DG Anderson, D Moscatelli
US Patent App. 17/347,791, 2021
12021
Gene delivery carrier
UC Palmiero, JC Kaczmarek, DG Anderson, D Moscatelli
US Patent 11,041,069, 2021
12021
Gene Delivery: Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium (Adv. Mater. 8/2019)
AK Patel, JC Kaczmarek, S Bose, KJ Kauffman, F Mir, MW Heartlein, ...
Advanced Materials 31 (8), 1970053, 2019
12019
Poly (beta-amino esters) and uses thereof
DG Anderson, KJ Kauffman, JC Kaczmarek, AK Patel
US Patent 11,696,953, 2023
2023
Development of polymer-lipid nanoparticles for potent mRNA delivery to the lung
JC Kaczmarek
Massachusetts Institute of Technology, 2018
2018
Gene delivery carrier
D Moscatelli, U Capasso Palmiero, D Anderson, J Kaczmarek
2017
系统目前无法执行此操作,请稍后再试。
文章 1–20