The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages CL Evavold, J Ruan, Y Tan, S Xia, H Wu, JC Kagan Immunity, 2017 | 1015 | 2017 |
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells I Zanoni, Y Tan, M Di Gioia, A Broggi, J Ruan, J Shi, CA Donado, F Shao, ... Science 352 (6290), 1232-1236, 2016 | 529 | 2016 |
Ubiquitination independent of E1 and E2 enzymes by bacterial effectors J Qiu, MJ Sheedlo, K Yu, Y Tan, ES Nakayasu, C Das, X Liu, ZQ Luo Nature 533 (7601), 120-124, 2016 | 369 | 2016 |
Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila W Zhu, S Banga, Y Tan, C Zheng, R Stephenson, J Gately, ZQ Luo PloS one 6 (3), e17638, 2011 | 332 | 2011 |
Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila MF Fontana, S Banga, KC Barry, X Shen, Y Tan, ZQ Luo, RE Vance PLoS pathogens 7 (2), e1001289, 2011 | 243 | 2011 |
Legionella pneumophila SidD is a deAMPylase that modifies Rab1 Y Tan, ZQ Luo Nature 475 (7357), 506-509, 2011 | 242 | 2011 |
IFN-[lambda] suppresses intestinal inflammation by non-translational regulation of neutrophil function A Broggi, Y Tan, F Granucci, I Zanoni Nature immunology 18, 1084, 2017 | 234 | 2017 |
Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination Y Tan, RJ Arnold, ZQ Luo Proceedings of the National Academy of Sciences 108 (52), 21212-21217, 2011 | 226 | 2011 |
Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii C Chen, S Banga, K Mertens, MM Weber, I Gorbaslieva, Y Tan, ZQ Luo, ... Proceedings of the National Academy of Sciences 107 (50), 21755-21760, 2010 | 225 | 2010 |
A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide Y Tan, JC Kagan Molecular cell 54 (2), 212-223, 2014 | 222 | 2014 |
By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation I Zanoni, Y Tan, M Di Gioia, JR Springstead, JC Kagan Immunity 47 (4), 697-709. e3, 2017 | 198 | 2017 |
Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria Y Tan, I Zanoni, TW Cullen, AL Goodman, JC Kagan Immunity 43 (5), 909-922, 2015 | 186 | 2015 |
Identification of Coxiella burnetii type IV secretion substrates required for intracellular replication and Coxiella-containing vacuole formation MM Weber, C Chen, K Rowin, K Mertens, G Galvan, H Zhi, CM Dealing, ... Journal of bacteriology 195 (17), 3914-3924, 2013 | 125 | 2013 |
Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination MJ Sheedlo, J Qiu, Y Tan, LN Paul, ZQ Luo, C Das Proceedings of the National Academy of Sciences 112 (49), 15090-15095, 2015 | 114 | 2015 |
Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility Y Tan, JC Kagan Cell, 2019 | 113 | 2019 |
A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin Y Liu, W Zhu, Y Tan, ES Nakayasu, CJ Staiger, ZQ Luo PLoS pathogens 13 (1), e1006186, 2017 | 51 | 2017 |
Microbe‐inducible trafficking pathways that control Toll‐like receptor signaling Y Tan, JC Kagan Traffic 18 (1), 6-17, 2017 | 35 | 2017 |
Legionella pneumophila regulates host cell motility by targeting Phldb2 with a 14-3-3ζ-dependent protease effector L Song, J Luo, H Wang, D Huang, Y Tan, Y Liu, Y Wang, K Yu, Y Zhang, ... Elife 11, e73220, 2022 | 19 | 2022 |
Biochemical Isolation of the Myddosome from Murine Macrophages Y Tan, JC Kagan Innate Immune Activation, 79-95, 2018 | 7 | 2018 |
Take it and release it: The use of the Rab1 small GTPase at a bacterium's will Y Tan, ZQ Luo Cellular logistics 1 (4), 125-127, 2011 | 5 | 2011 |