Synthesis, antifungal activity, and molecular modeling studies of new inverted oxime ethers of oxiconazole A Rossello, S Bertini, A Lapucci, M Macchia, A Martinelli, S Rapposelli, ... Journal of medicinal chemistry 45 (22), 4903-4912, 2002 | 169 | 2002 |
Matrix metalloproteinase inhibitors: new challenges in the era of post broad-spectrum inhibitors E Nuti, T Tuccinardi, A Rossello Current pharmaceutical design 13 (20), 2087-2100, 2007 | 135 | 2007 |
The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cells O Rosso, T Piazza, I Bongarzone, A Rossello, D Mezzanzanica, ... Molecular Cancer Research 5 (12), 1246-1253, 2007 | 133 | 2007 |
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies M Bozdag, M Ferraroni, E Nuti, D Vullo, A Rossello, F Carta, A Scozzafava, ... Bioorganic & Medicinal Chemistry 22 (1), 334-340, 2014 | 109 | 2014 |
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) A Rossello, E Nuti, E Orlandini, P Carelli, S Rapposelli, M Macchia, ... Bioorganic & medicinal chemistry 12 (9), 2441-2450, 2004 | 94 | 2004 |
Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)-and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3 … T Tuccinardi, A Martinelli, E Nuti, P Carelli, F Balzano, G Uccello-Barretta, ... Bioorganic & medicinal chemistry 14 (12), 4260-4276, 2006 | 92 | 2006 |
Vascular ADAM17 as a novel therapeutic target in mediating cardiovascular hypertrophy and perivascular fibrosis induced by angiotensin II T Takayanagi, SJ Forrester, T Kawai, T Obama, T Tsuji, KJ Elliott, E Nuti, ... Hypertension 68 (4), 949-955, 2016 | 79 | 2016 |
New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties MC Breschi, V Calderone, M Digiacomo, M Macchia, A Martelli, ... Journal of medicinal chemistry 49 (8), 2628-2639, 2006 | 76 | 2006 |
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma P Gabelloni, E Da Pozzo, S Bendinelli, B Costa, E Nuti, F Casalini, ... Neuroscience 168 (2), 514-522, 2010 | 73 | 2010 |
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential … E Nuti, F Casalini, SI Avramova, S Santamaria, G Cercignani, L Marinelli, ... Journal of medicinal chemistry 52 (15), 4757-4773, 2009 | 66 | 2009 |
Design, synthesis and molecular modeling study of iminodiacetyl monohydroxamic acid derivatives as MMP inhibitors MA Santos, SM Marques, T Tuccinardi, P Carelli, L Panelli, A Rossello Bioorganic & medicinal chemistry 14 (22), 7539-7550, 2006 | 60 | 2006 |
Deficient natural killer cell NKp30‐mediated function and altered NCR3 splice variants in hepatocellular carcinoma S Mantovani, B Oliviero, A Lombardi, S Varchetta, D Mele, A Sangiovanni, ... Hepatology 69 (3), 1165-1179, 2019 | 57 | 2019 |
Design, synthesis, biological evaluation, and NMR studies of a new series of arylsulfones as selective and potent matrix metalloproteinase-12 inhibitors E Nuti, L Panelli, F Casalini, SI Avramova, E Orlandini, S Santamaria, ... Journal of medicinal chemistry 52 (20), 6347-6361, 2009 | 56 | 2009 |
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates E Nuti, E Orlandini, S Nencetti, A Rossello, A Innocenti, A Scozzafava, ... Bioorganic & medicinal chemistry 15 (6), 2298-2311, 2007 | 56 | 2007 |
Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate− benzenesulfonamide conjugates SM Marques, E Nuti, A Rossello, CT Supuran, T Tuccinardi, A Martinelli, ... Journal of medicinal chemistry 51 (24), 7968-7979, 2008 | 55 | 2008 |
Strategies to target ADAM17 in disease: from its discovery to the iRhom revolution M Calligaris, D Cuffaro, S Bonelli, DP Spanò, A Rossello, E Nuti, ... Molecules 26 (4), 944, 2021 | 54 | 2021 |
Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups M Bozdag, M Ferraroni, F Carta, D Vullo, L Lucarini, E Orlandini, ... Journal of Medicinal Chemistry 57 (21), 9152-9167, 2014 | 54 | 2014 |
Crystallization of bi-functional ligand protein complexes C Antoni, L Vera, L Devel, MP Catalani, B Czarny, E Cassar-Lajeunesse, ... Journal of Structural Biology 182 (3), 246-254, 2013 | 54 | 2013 |
Activated leukocyte cell adhesion molecule soluble form: a potential biomarker of epithelial ovarian cancer is increased in type II tumors G Carbotti, AM Orengo, D Mezzanzanica, M Bagnoli, A Brizzolara, ... International journal of cancer 132 (11), 2597-2605, 2013 | 54 | 2013 |
Biphenyl sulfonylamino methyl bisphosphonic acids as inhibitors of matrix metalloproteinases and bone resorption MT Rubino, M Agamennone, C Campestre, P Campiglia, V Cremasco, ... ChemMedChem 6 (7), 1258-1268, 2011 | 51 | 2011 |