Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen AMJ Shapiro, JRT Lakey, EA Ryan, GS Korbutt, E Toth, GL Warnock, ... New England Journal of Medicine 343 (4), 230-238, 2000 | 6797 | 2000 |
International trial of the Edmonton protocol for islet transplantation AMJ Shapiro, C Ricordi, BJ Hering, H Auchincloss, R Lindblad, ... New England Journal of Medicine 355 (13), 1318-1330, 2006 | 2484 | 2006 |
Five-year follow-up after clinical islet transplantation EA Ryan, BW Paty, PA Senior, D Bigam, E Alfadhli, NM Kneteman, ... Diabetes 54 (7), 2060-2069, 2005 | 2149 | 2005 |
Hepatitis C virus replication in mice with chimeric human livers DF Mercer, DE Schiller, JF Elliott, DN Douglas, C Hao, A Rinfret, ... Nature medicine 7 (8), 927-933, 2001 | 1169 | 2001 |
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol EA Ryan, JRT Lakey, RV Rajotte, GS Korbutt, T Kin, S Imes, ... Diabetes 50 (4), 710-719, 2001 | 1161 | 2001 |
Successful islet transplantation: continued insulin reserve provides long-term glycemic control EA Ryan, JRT Lakey, BW Paty, S Imes, GS Korbutt, NM Kneteman, ... Diabetes 51 (7), 2148-2157, 2002 | 1011 | 2002 |
Stem cell-derived exosomes as nanotherapeutics for autoimmune and neurodegenerative disorders M Riazifar, MR Mohammadi, EJ Pone, A Yeri, C Lasser, AI Segaliny, ... ACS nano 13 (6), 6670-6688, 2019 | 398 | 2019 |
Variables in organ donors that affect the recovery of human islets of langerhans1 JRT Lakey, GL Warnock, RV Rajotte, ME Suarez-Almazor, Z Ao, ... Transplantation 61 (7), 1047-1053, 1996 | 376 | 1996 |
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas E Hao, B Tyrberg, P Itkin-Ansari, JRT Lakey, I Geron, EZ Monosov, ... Nature medicine 12 (3), 310-316, 2006 | 302 | 2006 |
Insulin-stimulated insulin secretion in single pancreatic beta cells CA Aspinwall, JRT Lakey, RT Kennedy Journal of Biological Chemistry 274 (10), 6360-6365, 1999 | 292 | 1999 |
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome CN Street, JRT Lakey, AMJ Shapiro, S Imes, RV Rajotte, EA Ryan, ... Diabetes 53 (12), 3107-3114, 2004 | 279 | 2004 |
A novel approach to increase human islet cell mass while preserving β-cell function GM Beattie, AMP Montgomery, AD Lopez, E Hao, B Perez, ML Just, ... Diabetes 51 (12), 3435-3439, 2002 | 275 | 2002 |
Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet β-cells from pancreatic duct cells and an increase in functional β-cell mass WL Suarez-Pinzon, JRT Lakey, SJ Brand, A Rabinovitch The Journal of Clinical Endocrinology & Metabolism 90 (6), 3401-3409, 2005 | 258 | 2005 |
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion JRT Lakey, GL Warnock, AMJ Shapiro, GS Korbutt, Z Ao, NM Kneteman, ... Cell transplantation 8 (3), 285-292, 1999 | 254 | 1999 |
Comparison of aortic valve allograft decellularization techniques in the rat SR Meyer, B Chiu, TA Churchill, L Zhu, JRT Lakey, DB Ross Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2006 | 250 | 2006 |
Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production A Rabinovitch, WL Suarez-Pinzon, K Strynadka, JR Lakey, RV Rajotte The Journal of Clinical Endocrinology & Metabolism 81 (9), 3197-3202, 1996 | 235 | 1996 |
Expansion of mesenchymal stem cells from human pancreatic ductal epithelium KL Seeberger, JM Dufour, AMJ Shapiro, JRT Lakey, RV Rajotte, ... Laboratory investigation 86 (2), 141-153, 2006 | 234 | 2006 |
Strategic opportunities in clinical islet transplantation AMJ Shapiro, JRT Lakey, BW Paty, PA Senior, DL Bigam, EA Ryan Transplantation 79 (10), 1304-1307, 2005 | 199 | 2005 |
β-Score: an assessment of β-cell function after islet transplantation EA Ryan, BW Paty, PA Senior, JRT Lakey, D Bigam, AMJ Shapiro Diabetes care 28 (2), 343-347, 2005 | 195 | 2005 |
A human β-cell line for transplantation therapy to control type 1 diabetes M Narushima, N Kobayashi, T Okitsu, Y Tanaka, SA Li, Y Chen, A Miki, ... Nature biotechnology 23 (10), 1274-1282, 2005 | 189 | 2005 |