Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation AD Brunner, M Thielert, C Vasilopoulou, C Ammar, F Coscia, A Mund, ... Molecular systems biology 18 (3), e10798, 2022 | 383 | 2022 |
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts MA Eckert, F Coscia, A Chryplewicz, JW Chang, KM Hernandez, S Pan, ... Nature 569 (7758), 723-728, 2019 | 383 | 2019 |
Deep Visual Proteomics defines single-cell identity and heterogeneity A Mund, F Coscia, A Kriston, R Hollandi, F Kovács, AD Brunner, E Migh, ... Nature Biotechnology 40 (8), 1231-1240, 2022 | 247* | 2022 |
Integrative proteomic profiling of ovarian cancer cell lines reveals precursor cell associated proteins and functional status F Coscia, KM Watters, M Curtis, MA Eckert, CY Chiang, S Tyanova, ... Nature communications 7 (1), 12645, 2016 | 209 | 2016 |
A knowledge graph to interpret clinical proteomics data A Santos, AR Colaço, AB Nielsen, L Niu, M Strauss, PE Geyer, F Coscia, ... Nature biotechnology 40 (5), 692-702, 2022 | 161 | 2022 |
Multi-level proteomics identifies CT45 as a chemosensitivity mediator and immunotherapy target in ovarian cancer F Coscia, E Lengyel, J Duraiswamy, B Ashcroft, M Bassani-Sternberg, ... Cell 175 (1), 159-170. e16, 2018 | 151 | 2018 |
A streamlined mass spectrometry–based proteomics workflow for large‐scale FFPE tissue analysis F Coscia, S Doll, JM Bech, L Schweizer, A Mund, E Lengyel, J Lindebjerg, ... The Journal of pathology 251 (1), 100-112, 2020 | 140 | 2020 |
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin B Dyring-Andersen, MB Løvendorf, F Coscia, A Santos, LBP Møller, ... Nature communications 11 (1), 5587, 2020 | 90 | 2020 |
Identification of early neurodegenerative pathways in progressive multiple sclerosis M Kaufmann, AL Schaupp, R Sun, F Coscia, CA Dendrou, A Cortes, ... Nature Neuroscience 25 (7), 944-955, 2022 | 75 | 2022 |
Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex G Zhang, T Kruse, C Guasch Boldú, DH Garvanska, F Coscia, M Mann, ... The EMBO Journal 38 (7), e100977, 2019 | 65 | 2019 |
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities T Kruse, C Benz, DH Garvanska, R Lindqvist, F Mihalic, F Coscia, R Inturi, ... Nature Communications 12 (1), 6761, 2021 | 58 | 2021 |
FAM111 protease activity undermines cellular fitness and is amplified by gain‐of‐function mutations in human disease S Hoffmann, S Pentakota, A Mund, P Haahr, F Coscia, M Gallo, M Mann, ... EMBO reports 21 (10), e50662, 2020 | 48 | 2020 |
Homology-directed repair protects the replicating genome from metabolic assaults K Somyajit, J Spies, F Coscia, U Kirik, MB Rask, JH Lee, KJ Neelsen, ... Developmental cell 56 (4), 461-477. e7, 2021 | 43 | 2021 |
Rapid proteomic analysis for solid tumors reveals LSD 1 as a drug target in an end‐stage cancer patient S Doll, MC Kriegmair, A Santos, M Wierer, F Coscia, HM Neil, S Porubsky, ... Molecular oncology 12 (8), 1296-1307, 2018 | 41 | 2018 |
Regulated intramembrane proteolysis and degradation of murine epithelial cell adhesion molecule mEpCAM M Hachmeister, KD Bobowski, S Hogl, B Dislich, A Fukumori, C Eggert, ... PloS one 8 (8), e71836, 2013 | 41 | 2013 |
A novel inhibitory domain of Helicobacter pylori protein CagA reduces CagA effects on host cell biology C Pelz, S Steininger, C Weiss, F Coscia, R Vogelmann Journal of Biological Chemistry 286 (11), 8999-9008, 2011 | 34 | 2011 |
Mesothelial cell HIF1α expression is metabolically downregulated by metformin to prevent oncogenic tumor-stromal crosstalk PC Hart, HA Kenny, N Grassl, KM Watters, LM Litchfield, F Coscia, ... Cell reports 29 (12), 4086-4098. e6, 2019 | 33 | 2019 |
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition G Zonderland, R Vanzo, SA Gadi, E Martín-Doncel, F Coscia, A Mund, ... Molecular Cell 82 (18), 3350-3365. e7, 2022 | 14 | 2022 |
K27‐linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation RF Shearer, D Typas, F Coscia, S Schovsbo, T Kruse, A Mund, N Mailand The EMBO Journal 41 (9), e110145, 2022 | 14 | 2022 |
A framework for ultra-low-input spatial tissue proteomics A Makhmut, D Qin, S Fritzsche, J Nimo, J König, F Coscia Cell Systems 14 (11), 1002-1014. e5, 2023 | 9 | 2023 |