Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53‐independent pathway: implications for the possible role of dietary fibre in the prevention of … A Hague, AM Manning, KA Hanlon, D Hart, C Paraskeva, LI Huschtscha International journal of cancer 55 (3), 498-505, 1993 | 695 | 1993 |
Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate A Hague, DJE Elder, DJ Hicks, C Paraskeva International journal of cancer 60 (3), 400-406, 1995 | 550 | 1995 |
Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 … DJ Elder, DE Halton, A Hague, C Paraskeva Clinical cancer research: an official journal of the American Association …, 1997 | 522 | 1997 |
Apoptosis Is Induced by the Active Metabolite of Vitamin D3 and Its Analogue EB1089 in Colorectal Adenoma and Carcinoma Cells: Possible Implications for … GD Díaz, C Paraskeva, MG Thomas, L Binderup, A Hague Cancer research 60 (8), 2304-2312, 2000 | 423 | 2000 |
Apoptosis Is Induced by the Active Metabolite of Vitamin D3 and Its Analogue EB1089 in Colorectal Adenoma and Carcinoma Cells: Possible Implications for … GD Díaz, C Paraskeva, MG Thomas, L Binderup, A Hague Cancer research 60 (8), 2304-2312, 2000 | 423 | 2000 |
BCL-2 expression in human colorectal adenomas and carcinomas. A Hague, M Moorghen, D Hicks, M Chapman, C Paraskeva Oncogene 9 (11), 3367-3370, 1994 | 243 | 1994 |
Differential growth inhibition by the aspirin metabolite salicylate in human colorectal tumor cell lines: enhanced apoptosis in carcinoma and in vitro-transformed adenoma … DJE Elder, A Hague, DJ Hicks, C Paraskeva Cancer Research 56 (10), 2273-2276, 1996 | 239 | 1996 |
The role of butyrate in human colonic epithelial cells: an energy source or inducer of differentiation and apoptosis? A Hague, AJ Butt, C Paraskeva Proceedings of the Nutrition society 55 (3), 937-943, 1996 | 199 | 1996 |
Butyrate acts as a survival factor for colonic epithelial cells: further fuel for the in vivo versus in vitro debate A Hague, B Singh, C Paraskeva Gastroenterology 112 (3), 1036-1040, 1997 | 192 | 1997 |
The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines A Hague, C Paraskeva European Journal of Cancer Prevention 4 (5), 359-364, 1995 | 148 | 1995 |
The PI3K/Akt pathway in tumors of endocrine tissues HL Robbins, A Hague Frontiers in endocrinology 6, 188, 2016 | 146 | 2016 |
bcl‐2 and bak may play a pivotal role in sodium butyrate‐induced apoptosis in colonic epithelial cells; however overexpression of bcl‐2 does not protect against bak‐mediated … A Hague, GD Díaz, DJ Hicks, S Krajewski, JC Reed, C Paraskeva International Journal of Cancer 72 (5), 898-905, 1997 | 141 | 1997 |
BAG-1 expression and function in human cancer RI Cutress, PA Townsend, M Brimmell, AC Bateman, A Hague, ... British journal of cancer 87 (8), 834-839, 2002 | 125 | 2002 |
The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis HA Minter, JW Eveson, S Huntley, DJE Elder, A Hague Clinical cancer research 9 (5), 1885-1897, 2003 | 109 | 2003 |
Loss of apc protein expressed by human colonic epithelial cells and the appearance of a specific low‐molecular‐weight form is associated with apoptosis IN vitro SJ Browne, AC Williams, A Hague, AJ Butt, C Paraskeva International journal of cancer 59 (1), 56-64, 1994 | 90 | 1994 |
BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-κB activity NK Clemo, TJ Collard, SL Southern, KD Edwards, M Moorghen, ... Carcinogenesis 29 (4), 849-857, 2008 | 78 | 2008 |
Nuclear BAG-1 expression inhibits apoptosis in colorectal adenoma-derived epithelial cells JD Barnes, NJ Arhel, SS Lee, A Sharp, M Al-Okail, G Packham, A Hague, ... Apoptosis 10, 301-311, 2005 | 73 | 2005 |
Caspase‐3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and … A Hague, JW Eveson, M MacFarlane, S Huntley, N Janghra, S Thavaraj The Journal of Pathology: A Journal of the Pathological Society of Great …, 2004 | 63 | 2004 |
Apoptosis and disease: a matter of cell fate A Hague, C Paraskeva Cell Death & Differentiation 11 (12), 1366-1372, 2004 | 62 | 2004 |
Cell-cell contact and specific cytokines inhibit apoptosis of colonic epithelial cells: growth factors protect against c-myc-independent apoptosis A Hague, DJ Hicks, TS Bracey, C Paraskeva British journal of cancer 75 (7), 960-968, 1997 | 60 | 1997 |