| Intrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1 JY Lee, Y Bai, UV Chembazhi, S Peng, K Yum, LM Luu, LD Hagler, ... Proceedings of the National Academy of Sciences 116 (18), 8709-8714, 2019 | 48 | 2019 |
| Integrating display and delivery functionality with a cell penetrating peptide mimic as a scaffold for intracellular multivalent multitargeting Y Bai, L Nguyen, Z Song, S Peng, JY Lee, N Zheng, I Kapoor, LD Hagler, ... Journal of the American Chemical Society 138 (30), 9498-9507, 2016 | 37 | 2016 |
| Structural basis for targeting T: T mismatch with triaminotriazine-acridine conjugate induces a U-shaped head-to-head four-way junction in CTG repeat DNA CM Chien, PC Wu, R Satange, CC Chang, ZL Lai, LD Hagler, ... Journal of the American Chemical Society 142 (25), 11165-11172, 2020 | 32 | 2020 |
| Development of novel macrocyclic small molecules that target CTG trinucleotide repeats JF Serrano, JY Lee, LD Curet, LD Hagler, SE Bonson, EJ Schuster, ... Bioorganic & medicinal chemistry 27 (13), 2978-2984, 2019 | 13 | 2019 |
| Expanded DNA and RNA trinucleotide repeats in myotonic dystrophy type 1 select their own multitarget, sequence-selective inhibitors LD Hagler, LM Luu, M Tonelli, JY Lee, SM Hayes, SE Bonson, JI Vergara, ... Biochemistry 59 (37), 3463-3472, 2020 | 11 | 2020 |
| Versatile target-guided screen for discovering bidirectional transcription inhibitors of a trinucleotide repeat disease LD Hagler, SB Krueger, LM Luu, AN Lanzendorf, NL Mitchell, JI Vergara, ... ACS Medicinal Chemistry Letters 12 (6), 935-940, 2021 | 8 | 2021 |
| A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4 C Sadée, LD Hagler, WR Becker, I Jarmoskaite, PP Vaidyanathan, ... Nature Communications 13 (1), 4522, 2022 | 7 | 2022 |
| Structure of an RNA helix with pyrimidine mismatches and cross-strand stacking EJ Montemayor, JM Virta, LD Hagler, SC Zimmerman, SE Butcher Acta Crystallographica Section F: Structural Biology Communications 75 (10 …, 2019 | 4 | 2019 |
| Assessing the feasibility and stability of uracil base flipping in RNA–small molecule complexes using molecular dynamics simulations LD Hagler, SE Bonson, PA Kocheril, SC Zimmerman Canadian Journal of Chemistry 98 (6), 261-269, 2020 | 3 | 2020 |
| SEISMICgraph: a web-based tool for RNA structure data visualization FF Wightman, G Yang, YJM des Taillades, C L’Esperance-Kerckhoff, ... bioRxiv, 2024 | | 2024 |
| This chapter was adapted from the following publications SB Krueger, LD Hagler, SE Bonson, STO Multitarget NUCLEIC ACID-TEMPLATED ASSEMBLY OF THERAPEUTIC AGENTS 59 (37), 21, 2022 | | 2022 |
| Relating structure and function: Discovery of novel inhibitors of myotonic dystrophy LD Hagler University of Illinois at Urbana-Champaign, 2020 | | 2020 |
| Template-assisted click chemistry as a therapuetic strategy for myotonic dystrophy type 1 (DM1) L Hagler, L Luu, S Zimmerman ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
