DENV inhibits type I IFN production in infected cells by cleaving human STING S Aguirre, AM Maestre, S Pagni, JR Patel, T Savage, D Gutman, ... Public Library of Science 8 (10), e1002934, 2012 | 556 | 2012 |
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection S Aguirre, P Luthra, MT Sanchez-Aparicio, AM Maestre, J Patel, ... Nature microbiology 2 (5), 1-11, 2017 | 366 | 2017 |
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response R Rajsbaum, GA Versteeg, S Schmid, AM Maestre, A Belicha-Villanueva, ... Immunity 40 (6), 880-895, 2014 | 157 | 2014 |
ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon JR Patel, A Jain, Y Chou, A Baum, T Ha, A Garcia-Sastre EMBO Reports, 10.1038/embor.2013.102, 2013 | 151 | 2013 |
Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of Type I interferon responses FW Santiago, LM Covaleda, MT Sanchez-Aparicio, JA Silvas, ... Journal of virology 88 (8), 4572-4585, 2014 | 127 | 2014 |
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA C Lässig, S Matheisl, KMJ Sparrer, CC de Oliveira Mann, M Moldt, ... Elife 4, e10859, 2015 | 110 | 2015 |
Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin S Tripathi, J Batra, W Cao, K Sharma, JR Patel, P Ranjan, A Kumar, ... Cell death & disease 4 (3), e562-e562, 2013 | 105 | 2013 |
Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice V Jeisy-Scott, WG Davis, JR Patel, JB Bowzard, WJ Shieh, SR Zaki, ... PloS one 6 (9), e25242, 2011 | 94 | 2011 |
RIG-I Detects mRNA of Intracellular Salmonella enterica Serovar Typhimurium during Bacterial Infection M Schmolke, JR Patel, E de Castro, MT Sánchez-Aparicio, MB Uccellini, ... mBio 5 (2), e01006-14, 2014 | 65 | 2014 |
RIG-I detects mRNA of intracellular Salmonella enterica serovar Typhimurium during bacterial infection M Schmolke, JR Patel, E de Castro, MT Sánchez-Aparicio, MB Uccellini, ... MBio 5 (2), e01006-14, 2014 | 65 | 2014 |
Activation and regulation of pathogen sensor RIG-I JR Patel, A García-Sastre Cytokine & growth factor reviews 25 (5), 513-523, 2014 | 59 | 2014 |
Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation F Ferrage, K Dutta, E Nistal-Villán, JR Patel, MT Sánchez-Aparicio, ... Structure 20 (12), 2048-2061, 2012 | 49 | 2012 |
RIG-I mediates an antiviral response to Crimean-Congo hemorrhagic fever virus JR Spengler, JR Patel, AK Chakrabarti, M Zivcec, A García-Sastre, ... Journal of virology 89 (20), 10219-10229, 2015 | 47 | 2015 |
Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α‐actinin‐4 for viral replication S Sharma, AK Mayank, H Nailwal, S Tripathi, JR Patel, JB Bowzard, ... The FEBS Journal 281 (13), 2899-2914, 2014 | 45 | 2014 |
Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein P Gaur, P Ranjan, S Sharma, JR Patel, JB Bowzard, SK Rahman, ... Journal of Biological Chemistry 287 (18), 15109-15117, 2012 | 40 | 2012 |
Cationic liposome–DNA complexes (CLDC) adjuvant enhances the immunogenicity and cross-protective efficacy of a pre-pandemic influenza A H5N1 vaccine in mice L Dong, F Liu, J Fairman, DK Hong, DB Lewis, T Monath, JF Warner, ... Vaccine 30 (2), 254-264, 2012 | 32 | 2012 |
NADPH oxidase 1 is associated with altered host survival and T cell phenotypes after influenza A virus infection in mice AR Hofstetter, JA De La Cruz, W Cao, J Patel, JA Belser, J McCoy, ... PloS one 11 (2), e0149864, 2016 | 26 | 2016 |
Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection. Nat Microbiol 2: 17037 S Aguirre, P Luthra, MT Sanchez-Aparicio, AM Maestre, J Patel, ... | 21 | 2017 |
Infection of lung epithelial cells with pandemic 2009 A (H1N1) influenza viruses reveals isolate-specific differences in infectivity and host cellular responses JR Patel, KP Vora, S Tripathi, H Zeng, TM Tumpey, JM Katz, S Sambhara, ... Viral immunology 24 (2), 89-99, 2011 | 13 | 2011 |
Correction: ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA C Lässig, S Matheisl, KMJ Sparrer, CC de Oliveira Mann, M Moldt, ... eLife 5, 2016 | 9 | 2016 |