Tumour exosome integrins determine organotropic metastasis A Hoshino, B Costa-Silva, TL Shen, G Rodrigues, A Hashimoto, ... Nature 527 (7578), 329-335, 2015 | 4598 | 2015 |
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver B Costa-Silva, NM Aiello, AJ Ocean, S Singh, H Zhang, BK Thakur, ... Nature cell biology 17 (6), 816-826, 2015 | 2625 | 2015 |
Extracellular vesicle and particle biomarkers define multiple human cancers A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ... Cell 182 (4), 1044-1061. e18, 2020 | 859 | 2020 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 813 | 2018 |
MUC1 and HIF-1alpha signaling crosstalk induces anabolic glucose metabolism to impart gemcitabine resistance to pancreatic cancer SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika, E Vernucci, RJ King, ... Cancer cell 32 (1), 71-87. e7, 2017 | 474 | 2017 |
Enhancer reprogramming promotes pancreatic cancer metastasis JS Roe, CI Hwang, TDD Somerville, JP Milazzo, EJ Lee, B Da Silva, ... Cell 170 (5), 875-888. e20, 2017 | 392 | 2017 |
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring Y Shi, W Gao, NK Lytle, P Huang, X Yuan, AM Dann, M Ridinger-Saison, ... Nature 569 (7754), 131-135, 2019 | 341 | 2019 |
Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle G Wang, AK Biswas, W Ma, M Kandpal, C Coker, PM Grandgenett, ... Nature medicine 24 (6), 770-781, 2018 | 155 | 2018 |
Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma RG Fox, NK Lytle, DV Jaquish, FD Park, T Ito, J Bajaj, CS Koechlein, ... Nature 534 (7607), 407-411, 2016 | 143 | 2016 |
Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-Ras JP Eggers, PM Grandgenett, EC Collisson, ME Lewallen, J Tremayne, ... Clinical Cancer Research 17 (19), 6140-6150, 2011 | 122 | 2011 |
ADH‐1 suppresses N‐cadherin‐dependent pancreatic cancer progression Y Shintani, Y Fukumoto, N Chaika, PM Grandgenett, MA Hollingsworth, ... International journal of cancer 122 (1), 71-77, 2008 | 101 | 2008 |
Expression and function of the Trypanosoma brucei major surface protease (GP63) genes DJ LaCount, AE Gruszynski, PM Grandgenett, JD Bangs, JE Donelson Journal of Biological Chemistry 278 (27), 24658-24664, 2003 | 93 | 2003 |
The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF ME Behrens, PM Grandgenett, JM Bailey, PK Singh, CH Yi, F Yu, ... Oncogene 29 (42), 5667-5677, 2010 | 92 | 2010 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8: 1112–1129. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 90 | |
Rosiglitazone and Gemcitabine in combination reduces immune suppression and modulates T cell populations in pancreatic cancer SK Bunt, AM Mohr, JM Bailey, PM Grandgenett, MA Hollingsworth Cancer immunology, immunotherapy 62, 225-236, 2013 | 78 | 2013 |
A function for a specific zinc metalloprotease of African trypanosomes PM Grandgenett, K Otsu, HR Wilson, ME Wilson, JE Donelson PLoS pathogens 3 (10), e150, 2007 | 72 | 2007 |
Metabolic programming of distinct cancer stem cells promotes metastasis of pancreatic ductal adenocarcinoma RK Nimmakayala, F Leon, S Rachagani, S Rauth, P Nallasamy, ... Oncogene 40 (1), 215-231, 2021 | 71 | 2021 |
Oncofetal chondroitin sulfate glycosaminoglycans are key players in integrin signaling and tumor cell motility TM Clausen, MA Pereira, N Al Nakouzi, HZ Oo, MØ Agerbæk, S Lee, ... Molecular Cancer Research 14 (12), 1288-1299, 2016 | 67 | 2016 |
Tumour extracellular vesicles and particles induce liver metabolic dysfunction G Wang, J Li, L Bojmar, H Chen, Z Li, GC Tobias, M Hu, EA Homan, ... Nature 618 (7964), 374-382, 2023 | 61 | 2023 |
MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer P Radhakrishnan, AM Mohr, PM Grandgenett, MM Steele, SK Batra, ... PloS one 8 (10), e73356, 2013 | 57 | 2013 |