Reversal of tumoral immune resistance by inhibition of tryptophan 2, 3-dioxygenase L Pilotte, P Larrieu, V Stroobant, D Colau, E Dolušić, R Frédérick, ... Proceedings of the National Academy of Sciences 109 (7), 2497-2502, 2012 | 613 | 2012 |
Differential scanning calorimetry in life science: thermodynamics, stability, molecular recognition and application in drug design G Bruylants, J Wouters, C Michaux Current medicinal chemistry 12 (17), 2011-2020, 2005 | 451 | 2005 |
Pharmaceutical salts and co-crystals J Wouters, L Quéré Royal Society of Chemistry, 2011 | 248 | 2011 |
Structural aspects of monoamine oxidase and its reversible J Wouters Curr Med Chem 5 (2), 137-162, 1998 | 235 | 1998 |
Tryptophan 2, 3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl) ethenyl) indoles as potential anticancer immunomodulators E Dolušić, P Larrieu, L Moineaux, V Stroobant, L Pilotte, D Colau, ... Journal of medicinal chemistry 54 (15), 5320-5334, 2011 | 213 | 2011 |
Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling G Labar, C Bauvois, F Borel, JL Ferrer, J Wouters, DM Lambert Chembiochem 11 (2), 218-227, 2010 | 209 | 2010 |
The endoxylanases from family 11: computer analysis of protein sequences reveals important structural and phylogenetic relationships A Sapag, J Wouters, C Lambert, P De Ioannes, J Eyzaguirre, E Depiereux Journal of Biotechnology 95 (2), 109-131, 2002 | 172 | 2002 |
Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2, 4-diones as fatty acid amide hydrolase inhibitors templates GG Muccioli, N Fazio, GKE Scriba, W Poppitz, F Cannata, JH Poupaert, ... Journal of medicinal chemistry 49 (1), 417-425, 2006 | 148 | 2006 |
A rapid and efficient microwave-assisted synthesis of hydantoins and thiohydantoins GG Muccioli, JH Poupaert, J Wouters, B Norberg, W Poppitz, GKE Scriba, ... Tetrahedron 59 (8), 1301-1307, 2003 | 132 | 2003 |
Pharmaceutical salts and cocrystals involving amino acids: a brief structural overview of the state-of-art A Tilborg, B Norberg, J Wouters European journal of medicinal chemistry 74, 411-426, 2014 | 130 | 2014 |
A review on the monoacylglycerol lipase: at the interface between fat and endocannabinoid signalling G Labar, J Wouters, DM Lambert Current medicinal chemistry 17 (24), 2588-2607, 2010 | 128 | 2010 |
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase M Roovers, J Wouters, JM Bujnicki, C Tricot, V Stalon, H Grosjean, ... Nucleic acids research 32 (2), 465-476, 2004 | 125 | 2004 |
Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B G Rondelet, T Dal Maso, L Willems, J Wouters Journal of structural biology 194 (3), 357-367, 2016 | 124 | 2016 |
Comparing the crystallization and polymorphic behaviour of saturated and unsaturated monoglycerides J Vereecken, W Meeussen, I Foubert, A Lesaffer, J Wouters, K Dewettinck Food research international 42 (10), 1415-1425, 2009 | 115 | 2009 |
Analysis of conserved active site residues in monoamine oxidase A and B and their three-dimensional molecular modeling RM Geha, K Chen, J Wouters, F Ooms, JC Shih Journal of Biological Chemistry 277 (19), 17209-17216, 2002 | 114 | 2002 |
Supramolecular Wiring of Benzo‐1, 3‐chalcogenazoles through Programmed Chalcogen Bonding Interactions A Kremer, A Fermi, N Biot, J Wouters, D Bonifazi Chemistry–A European Journal 22 (16), 5665-5675, 2016 | 112 | 2016 |
Synthesis and evaluation of β-carboline derivatives as potential monoamine oxidase inhibitors J Reniers, S Robert, R Frederick, B Masereel, S Vincent, J Wouters Bioorganic & medicinal chemistry 19 (1), 134-144, 2011 | 110 | 2011 |
Cation‐π (Na+‐Trp) interactions in the crystal structure of tetragonal lysozyme J Wouters Protein Science 7 (11), 2472-2475, 1998 | 108 | 1998 |
Catalytic mechanism of Escherichia coli isopentenyl diphosphate isomerase involves Cys-67, Glu-116, and Tyr-104 as suggested by crystal structures of complexes with transition … J Wouters, Y Oudjama, SJ Barkley, C Tricot, V Stalon, L Droogmans, ... Journal of Biological Chemistry 278 (14), 11903-11908, 2003 | 107 | 2003 |
Novel trisubstituted harmine derivatives with original in vitro anticancer activity R Frédérick, C Bruyère, C Vancraeynest, J Reniers, C Meinguet, L Pochet, ... Journal of medicinal chemistry 55 (14), 6489-6501, 2012 | 98 | 2012 |