| Deciphering the evolution of cephalosporin resistance to ceftolozane-tazobactam in Pseudomonas aeruginosa MD Barnes, MA Taracila, JD Rutter, CR Bethel, I Galdadas, AM Hujer, ... MBio 9 (6), 10.1128/mbio. 02085-18, 2018 | 72 | 2018 |
| Multiscale simulations reveal IRMOF-74-III as a potent drug carrier for gemcitabine delivery M Kotzabasaki, I Galdadas, E Tylianakis, E Klontzas, Z Cournia, ... Journal of Materials Chemistry B 5 (18), 3277-3282, 2017 | 65 | 2017 |
| Insights into the mechanism of the PIK3CA E545K activating mutation using MD simulations H Leontiadou, I Galdadas, C Athanasiou, Z Cournia Scientific reports 8 (1), 15544, 2018 | 63 | 2018 |
| Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant S Ilmjärv, F Abdul, S Acosta-Gutiérrez, C Estarellas, I Galdadas, ... Scientific reports 11 (1), 13705, 2021 | 59 | 2021 |
| Allosteric communication in class A β-lactamases occurs via cooperative coupling of loop dynamics I Galdadas, S Qu, ASF Oliveira, E Olehnovics, AR Mack, MF Mojica, ... Elife 10, e66567, 2021 | 59 | 2021 |
| Defining the architecture of KPC-2 Carbapenemase: identifying allosteric networks to fight antibiotics resistance I Galdadas, S Lovera, G Pérez-Hernández, MD Barnes, J Healy, ... Scientific Reports 8 (1), 12916, 2018 | 39 | 2018 |
| Structural basis of the effect of activating mutations on the EGF receptor I Galdadas, L Carlino, RA Ward, SJ Hughes, S Haider, FL Gervasio Elife 10, e65824, 2021 | 34 | 2021 |
| Unravelling the effect of the E545K mutation on PI3Kα kinase I Galdadas, FL Gervasio, Z Cournia Chemical science 11 (13), 3511-3515, 2020 | 22 | 2020 |
| Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography A Borsatto, O Akkad, I Galdadas, SMS Damfo, S Haider, F Kozielski, ... eLife 11 (e81167), 2022 | 18 | 2022 |
| Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation P Juyoux, I Galdadas, D Gobbo, J von Velsen, M Pelosse, M Tully, ... Science 381 (6663), 1217-1225, 2023 | 17 | 2023 |
| Design, synthesis, and anticancer activity of a selenium-containing galectin-3 and galectin-9N inhibitor S Di Gaetano, L Pirone, I Galdadas, S Traboni, A Iadonisi, E Pedone, ... International Journal of Molecular Sciences 23 (5), 2581, 2022 | 8 | 2022 |
| Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers RS Iyer, SR Needham, I Galdadas, BM Davis, SK Roberts, RCH Man, ... Nature Communications 15 (1), 2130, 2024 | 6 | 2024 |
| The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm L Wehrli, I Galdadas, L Voirol, M Smieško, Y Cambet, V Jaquet, S Guerrier, ... Frontiers in Cell and Developmental Biology 11, 1221578, 2023 | 4 | 2023 |
| Drug-Membrane Interactions in the Renin Angiotensin System D Ntountaniotis, TF Kellici, P Gkeka, Z Cournia, I Galdadas, G Mali, ... Thermodynamics and Biophysics of Biomedical Nanosystems: Applications and …, 2019 | 4 | 2019 |
| The effect of S427F mutation on RXRα activity depends on its dimeric partner I Galdadas, V Bonis, P Vgenopoulou, M Papadourakis, P Kakoulidis, ... Chemical Science 12 (44), 14700-14710, 2021 | 3 | 2021 |
| When two kinases go for a dance I Galdadas, FL Gervasio, P Juyoux TheScienceBreaker 10 (3), 2024 | | 2024 |
| Understanding the effect of oncogenic mutations on kinases I Galdadas UCL (University College London), 2021 | | 2021 |
| Νovel small molecule modulators of the hotspot PIK3CA mutants identified by computational and experimental approaches Z Cournia, P Gkeka, H Leontiadou, I Galdadas, C Athanasiou, ... Cancer Research 79 (13_Supplement), 3918-3918, 2019 | | 2019 |
