Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ... Cell 161 (7), 1681-1696, 2015 | 2754 | 2015 |
Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment Q Wang, B Hu, X Hu, H Kim, M Squatrito, L Scarpace, AC deCarvalho, ... Cancer cell 32 (1), 42-56. e6, 2017 | 1553 | 2017 |
Trends in oxidative aging theories FL Muller, MS Lustgarten, Y Jang, A Richardson, H Van Remmen Free Radical Biology and Medicine 43 (4), 477-503, 2007 | 1434 | 2007 |
Telomere dysfunction induces metabolic and mitochondrial compromise E Sahin, S Colla, M Liesa, J Moslehi, FL Müller, M Guo, M Cooper, ... Nature 470 (7334), 359-365, 2011 | 1407 | 2011 |
Complex III releases superoxide to both sides of the inner mitochondrial membrane FL Muller, Y Liu, H Van Remmen Journal of Biological Chemistry 279 (47), 49064-49073, 2004 | 1312 | 2004 |
Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function A Viale, P Pettazzoni, CA Lyssiotis, H Ying, N Sánchez, M Marchesini, ... Nature 514 (7524), 628-632, 2014 | 1211 | 2014 |
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice M Jaskelioff, FL Muller, JH Paik, E Thomas, S Jiang, AC Adams, E Sahin, ... Nature 469 (7328), 102-106, 2011 | 1021 | 2011 |
An inhibitor of oxidative phosphorylation exploits cancer vulnerability JR Molina, Y Sun, M Protopopova, S Gera, M Bandi, C Bristow, T McAfoos, ... Nature medicine 24 (7), 1036-1046, 2018 | 750 | 2018 |
Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy FL Muller, W Song, Y Liu, A Chaudhuri, S Pieke-Dahl, R Strong, ... Free Radical Biology and Medicine 40 (11), 1993-2004, 2006 | 546 | 2006 |
Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution H Kim, S Zheng, SS Amini, SM Virk, T Mikkelsen, DJ Brat, J Grimsby, ... Genome research 25 (3), 316-327, 2015 | 504 | 2015 |
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis J Paik, Z Ding, R Narurkar, S Ramkissoon, F Muller, WS Kamoun, ... Cell stem cell 5 (5), 540-553, 2009 | 488 | 2009 |
Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production FL Muller, W Song, YC Jang, Y Liu, M Sabia, A Richardson, ... American journal of physiology-Regulatory, integrative and comparative …, 2007 | 396 | 2007 |
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma LN Kwong, JC Costello, H Liu, S Jiang, TL Helms, AE Langsdorf, ... Nature medicine 18 (10), 1503-1510, 2012 | 390 | 2012 |
Passenger deletions generate therapeutic vulnerabilities in cancer FL Muller, S Colla, E Aquilanti, VE Manzo, G Genovese, J Lee, ... Nature 488 (7411), 337-342, 2012 | 366 | 2012 |
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration YC Jang, MS Lustgarten, Y Liu, FL Muller, A Bhattacharya, H Liang, ... The FASEB Journal 24 (5), 1376-1390, 2010 | 342 | 2010 |
The nature and mechanism of superoxide production by the electron transport chain: its relevance to aging F Muller Journal of the American Aging Association 23 (4), 227-253, 2000 | 302 | 2000 |
The in vivo gene expression signature of oxidative stress ES Han, FL Muller, VI Pérez, W Qi, H Liang, L Xi, C Fu, E Doyle, M Hickey, ... Physiological genomics 34 (1), 112-126, 2008 | 283 | 2008 |
Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging A Mansouri, FL Muller, Y Liu, R Ng, J Faulkner, M Hamilton, A Richardson, ... Mechanisms of ageing and development 127 (3), 298-306, 2006 | 258 | 2006 |
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer P Dey, J Baddour, F Muller, CC Wu, H Wang, WT Liao, Z Lan, A Chen, ... Nature 542 (7639), 119-123, 2017 | 257 | 2017 |
Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer Y Lissanu Deribe, Y Sun, C Terranova, F Khan, J Martinez-Ledesma, ... Nature medicine 24 (7), 1047-1057, 2018 | 245 | 2018 |