| IDO1 and kynurenine pathway metabolites activate PI3K-Akt signaling in the neoplastic colon epithelium to promote cancer cell proliferation and inhibit apoptosis KS Bishnupuri, DM Alvarado, AN Khouri, M Shabsovich, B Chen, ... Cancer research 79 (6), 1138-1150, 2019 | 172 | 2019 |
| Lactobacillus rhamnosus GG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal … TE Riehl, D Alvarado, X Ee, A Zuckerman, L Foster, V Kapoor, D Thotala, ... Gut 68 (6), 1003-1013, 2019 | 170 | 2019 |
| Epithelial indoleamine 2, 3-dioxygenase 1 modulates aryl hydrocarbon receptor and notch signaling to increase differentiation of secretory cells and alter mucus-associated … DM Alvarado, B Chen, M Iticovici, AI Thaker, N Dai, KL VanDussen, ... Gastroenterology 157 (4), 1093-1108. e11, 2019 | 114 | 2019 |
| Butyrate and mucosal inflammation: new scientific evidence supports clinical observation K Cushing, DM Alvarado, MA Ciorba Clinical and translational gastroenterology 6 (8), e108, 2015 | 102 | 2015 |
| Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer S Santhanam, DM Alvarado, MA Ciorba Translational Research 167 (1), 67-79, 2016 | 84 | 2016 |
| Interferon-induced IDO1 mediates radiation resistance and is a therapeutic target in colorectal cancer B Chen, DM Alvarado, M Iticovici, NS Kau, H Park, PJ Parikh, D Thotala, ... Cancer immunology research 8 (4), 451-464, 2020 | 73 | 2020 |
| Hyaluronic acid binding to TLR4 promotes proliferation and blocks apoptosis in colon cancer S Makkar, TE Riehl, B Chen, Y Yan, DM Alvarado, MA Ciorba, ... Molecular cancer therapeutics 18 (12), 2446-2456, 2019 | 63 | 2019 |
| Patient-derived small intestinal myofibroblasts direct perfused, physiologically responsive capillary development in a microfluidic Gut-on-a-Chip Model KM Seiler, A Bajinting, DM Alvarado, MA Traore, MM Binkley, WH Goo, ... Scientific reports 10 (1), 3842, 2020 | 39 | 2020 |
| CEACAMs serve as toxin-stimulated receptors for enterotoxigenic Escherichia coli A Sheikh, B Tumala, TJ Vickers, D Alvarado, MA Ciorba, TR Bhuiyan, ... Proceedings of the National Academy of Sciences 117 (46), 29055-29062, 2020 | 28 | 2020 |
| Hyaluronic acid promotes Lgr5+ stem cell proliferation and crypt fission through TLR4 and PGE2 transactivation of EGFR TE Riehl, D Alvarado, X Ee, MA Ciorba, WF Stenson American Journal of Physiology-Gastrointestinal and Liver Physiology 319 (1 …, 2020 | 28 | 2020 |
| Inflammatory bowel disease is associated with an increased risk of incident acute arterial events: analysis of the United Kingdom Biobank QA Alayo, EV Loftus Jr, A Yarur, D Alvarado, MA Ciorba, L de Las Fuentes, ... Clinical Gastroenterology and Hepatology 21 (3), 761-770. e13, 2023 | 19 | 2023 |
| Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice V Gonzalez-Perez, PL Martinez-Espinosa, M Sala-Rabanal, N Bharadwaj, ... Proceedings of the National Academy of Sciences 118 (3), e2019149118, 2021 | 19 | 2021 |
| Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice DM Alvarado, PA Coulombe Journal of Biological Chemistry 289 (28), 19435-19447, 2014 | 13 | 2014 |
| A role for salivary peptides in the innate defense against enterotoxigenic Escherichia coli JW Brown, A Badahdah, M Iticovici, TJ Vickers, DM Alvarado, ... The Journal of infectious diseases 217 (9), 1435-1441, 2018 | 12 | 2018 |
| Mesalamine reduces intestinal ACE2 expression without modifying SARS-CoV-2 infection or disease severity in mice DM Alvarado, J Son, LB Thackray, MF Gomez Castro, S Prasad, X Cui, ... Inflammatory bowel diseases 28 (2), 318-321, 2022 | 9 | 2022 |
| Stem cell and niche regulation in human short bowel syndrome VA Gazit, EA Swietlicki, MU Liang, A Surti, R McDaniel, M Geisman, ... JCI insight 5 (23), 2020 | 8 | 2020 |
| Serotonin receptors regulate inflammatory response in experimental colitis DM Alvarado, MA Ciorba The Journal of Nutrition 150 (7), 1678, 2020 | 7 | 2020 |
| PD-236 defining the signaling pathways and functional role for kynurenine metabolites in the normal and neoplastic colon epithelium S Santhanam, D Alvarado, A Khouri, B Dieckgraefe, K Bishnupuri, ... Inflammatory Bowel Diseases 23, S77-S78, 2017 | 6 | 2017 |
| RBM47 regulates intestinal injury and tumorigenesis by modifying proliferation, oxidative response, and inflammatory pathways S Soleymanjahi, V Blanc, EA Molitor, DM Alvarado, Y Xie, V Gazit, ... JCI insight 8 (9), 2023 | 5 | 2023 |
| Role of kynurenine pathway in gastrointestinal diseases DM Alvarado, S Santhanam, MA Ciorba Targeting the Broadly Pathogenic Kynurenine Pathway, 157-167, 2015 | 3 | 2015 |
