Nuclear receptor Rev-erbα is a critical lithium-sensitive component of the circadian clock L Yin, J Wang, PS Klein, MA Lazar Science 311 (5763), 1002-1005, 2006 | 699 | 2006 |
Precipitation of autoimmune diabetes with anti-PD-1 immunotherapy J Hughes, N Vudattu, M Sznol, S Gettinger, H Kluger, B Lupsa, KC Herold Diabetes care 38 (4), e55, 2015 | 369 | 2015 |
The orphan nuclear receptor Rev-erbα regulates circadian expression of plasminogen activator inhibitor type 1 J Wang, L Yin, MA Lazar Journal of Biological Chemistry 281 (45), 33842-33848, 2006 | 164 | 2006 |
Bifunctional role of Rev-erbα in adipocyte differentiation J Wang, MA Lazar Molecular and cellular biology 28 (7), 2213-2220, 2008 | 139 | 2008 |
Autoimmune diseases in children and adults with type 1 diabetes from the T1D Exchange Clinic Registry JW Hughes, TD Riddlesworth, LA DiMeglio, KM Miller, MR Rickels, ... The Journal of Clinical Endocrinology & Metabolism 101 (12), 4931-4937, 2016 | 112 | 2016 |
Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells AN Vomund, BH Zinselmeyer, J Hughes, B Calderon, C Valderrama, ... Proceedings of the National Academy of Sciences 112 (40), E5496-E5502, 2015 | 109 | 2015 |
Regulation of islet glucagon secretion: Beyond calcium JW Hughes, A Ustione, Z Lavagnino, DW Piston Diabetes, Obesity and Metabolism 20, 127-136, 2018 | 77 | 2018 |
Primary cilia control glucose homeostasis via islet paracrine interactions JW Hughes, JH Cho, HE Conway, MR DiGruccio, XW Ng, HF Roseman, ... Proceedings of the National Academy of Sciences 117 (16), 8912-8923, 2020 | 70 | 2020 |
Late-onset T1DM and older age predict risk of additional autoimmune disease JW Hughes, YK Bao, M Salam, P Joshi, CR Kilpatrick, K Juneja, D Nieves, ... Diabetes Care 42 (1), 32-38, 2019 | 32 | 2019 |
Refractory pituitary granulomatosis with polyangiitis (Wegener's) treated with rituximab J Hughes, G Barkhoudarian, P Pedro, ER Laws, E Mody, SE Inzucchi, ... Endocrine Practice 19 (1), e1-e7, 2013 | 32 | 2013 |
Immunomodulatory activity of humanized anti–IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes KC Herold, SL Bucktrout, X Wang, BW Bode, SE Gitelman, PA Gottlieb, ... JCI insight 4 (24), 2019 | 31 | 2019 |
Islet primary cilia motility controls insulin secretion JH Cho, ZA Li, L Zhu, BD Muegge, HF Roseman, EY Lee, T Utterback, ... Science advances 8 (38), eabq8486, 2022 | 25 | 2022 |
High-risk gastric pathology and prevalent autoimmune diseases in patients with pernicious anemia JW Hughes, BD Muegge, GS Tobin, M Litvin, L Sun, JB Saenz, ... Endocrine Practice 23 (11), 1297-1303, 2017 | 23 | 2017 |
Moyamoya syndrome causing stroke in young women with type 1 diabetes JW Hughes, JA Wyckoff, AS Hollander, CP Derdeyn, JB McGill Journal of Diabetes and its Complications 30 (8), 1640-1642, 2016 | 14 | 2016 |
Novel SIRT1 mutation linked to autoimmune diabetes in humans JW Hughes, KC Herold Cell metabolism 17 (3), 311-312, 2013 | 14 | 2013 |
Molecular phenotyping of single pancreatic islet leader beta cells by “Flash-Seq” P Chabosseau, F Yong, LF Delgadillo-Silva, EY Lee, R Melhem, S Li, ... Life Sciences 316, 121436, 2023 | 13 | 2023 |
Fluorescence imaging of beta cell primary cilia ZA Li, JH Cho, LG Woodhams, JW Hughes Frontiers in Endocrinology 13, 1004136, 2022 | 11 | 2022 |
Scanning electron microscopy of human islet cilia AJ Polino, S Sviben, I Melena, DW Piston, JW Hughes Proceedings of the National Academy of Sciences 120 (22), e2302624120, 2023 | 8 | 2023 |
Spontaneous restoration of functional β‐cell mass in obese SM/J mice MA Miranda, C Carson, CL St. Pierre, JF Macias‐Velasco, JW Hughes, ... Physiological reports 8 (20), e14573, 2020 | 8 | 2020 |
Clitoral epidermoid cyst presenting as pseudoclitoromegaly of pregnancy JW Hughes, MK Guess, A Hittelman, S Yip, J Astle, L Pal, SE Inzucchi, ... American Journal of Perinatology Reports 3 (01), 057-062, 2013 | 8 | 2013 |