Precise genome modification in the crop species Zea mays using zinc-finger nucleases VK Shukla, Y Doyon, JC Miller, RC DeKelver, EA Moehle, SE Worden, ... Nature 459 (7245), 437-441, 2009 | 1210 | 2009 |
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases Y Doyon, JM McCammon, JC Miller, F Faraji, C Ngo, GE Katibah, ... Nature biotechnology 26 (6), 702-708, 2008 | 1162 | 2008 |
In vivo genome editing restores haemostasis in a mouse model of haemophilia H Li, V Haurigot, Y Doyon, T Li, SY Wong, AS Bhagwat, N Malani, ... Nature 475 (7355), 217-221, 2011 | 756 | 2011 |
ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation Y Doyon, C Cayrou, M Ullah, AJ Landry, V Côté, W Selleck, WS Lane, ... Molecular cell 21 (1), 51-64, 2006 | 756 | 2006 |
Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans Y Doyon, W Selleck, WS Lane, S Tan, J Côté Molecular and cellular biology, 2004 | 720 | 2004 |
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures Y Doyon, TD Vo, MC Mendel, SG Greenberg, J Wang, DF Xia, JC Miller, ... Nature methods 8 (1), 74-79, 2011 | 532 | 2011 |
The highly conserved and multifunctional NuA4 HAT complex Y Doyon, J Côté Current opinion in genetics & development 14 (2), 147-154, 2004 | 477 | 2004 |
In vivo genome editing of the albumin locus as a platform for protein replacement therapy R Sharma, XM Anguela, Y Doyon, T Wechsler, RC DeKelver, S Sproul, ... Blood, The Journal of the American Society of Hematology 126 (15), 1777-1784, 2015 | 354 | 2015 |
Targeted transgene integration in plant cells using designed zinc finger nucleases CQ Cai, Y Doyon, WM Ainley, JC Miller, RC DeKelver, EA Moehle, ... Plant molecular biology 69, 699-709, 2009 | 283 | 2009 |
Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells JB Doyon, B Zeitler, J Cheng, AT Cheng, JM Cherone, Y Santiago, ... Nature cell biology 13 (3), 331-337, 2011 | 277 | 2011 |
The TIP60 complex regulates bivalent chromatin recognition by 53BP1 through direct H4K20me binding and H2AK15 acetylation K Jacquet, A Fradet-Turcotte, N Avvakumov, JP Lambert, C Roques, ... Molecular cell 62 (3), 409-421, 2016 | 266 | 2016 |
Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes M Ullah, N Pelletier, L Xiao, SP Zhao, K Wang, C Degerny, S Tahmasebi, ... Molecular and cellular biology, 2008 | 244 | 2008 |
Engineered cleavage half-domains Y Doyon, JC Miller US Patent 8,962,281, 2015 | 227 | 2015 |
HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail N Saksouk, N Avvakumov, KS Champagne, T Hung, Y Doyon, C Cayrou, ... Molecular cell 33 (2), 257-265, 2009 | 211 | 2009 |
Robust ZFN-mediated genome editing in adult hemophilic mice XM Anguela, R Sharma, Y Doyon, JC Miller, H Li, V Haurigot, ME Rohde, ... Blood, The Journal of the American Society of Hematology 122 (19), 3283-3287, 2013 | 209 | 2013 |
Eaf1 is the platform for NuA4 molecular assembly that evolutionarily links chromatin acetylation to ATP-dependent exchange of histone H2A variants A Auger, L Galarneau, M Altaf, A Nourani, Y Doyon, RT Utley, D Cronier, ... Molecular and cellular biology 28 (7), 2257-2270, 2008 | 208 | 2008 |
Transient cold shock enhances zinc-finger nuclease–mediated gene disruption Y Doyon, VM Choi, DF Xia, TD Vo, PD Gregory, MC Holmes Nature methods 7 (6), 459-460, 2010 | 200 | 2010 |
Cancer translocations in human cells induced by zinc finger and TALE nucleases M Piganeau, H Ghezraoui, A De Cian, L Guittat, M Tomishima, ... Genome research 23 (7), 1182-1193, 2013 | 173 | 2013 |
Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme J Wang, G Friedman, Y Doyon, NS Wang, CJ Li, JC Miller, KL Hua, JJ Yan, ... Genome research 22 (7), 1316-1326, 2012 | 171 | 2012 |
Marker-free coselection for CRISPR-driven genome editing in human cells D Agudelo, A Duringer, L Bozoyan, CC Huard, S Carter, J Loehr, ... Nature methods 14 (6), 615-620, 2017 | 167 | 2017 |