Early and protective microglial activation in Alzheimer’s disease: a prospective study using 18F-DPA-714 PET imaging L Hamelin, J Lagarde, G Dorothée, C Leroy, M Labit, RA Comley, ... Brain, 2016 | 438 | 2016 |
Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain. KP Ng, TA Pascoal, S Mathotaarachchi, J Therriault, MS Kang, M Shin, ... Alzheimer's Research & Therapy 9 (25), 2017 | 335 | 2017 |
Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding S Červenka, SE Pålhagen, RA Comley, G Panagiotidis, Z Cselényi, ... Brain 129 (8), 2017-2028, 2006 | 306 | 2006 |
Imaging Dopamine D3 Receptors in the Human Brain with Positron Emission Tomography, [11C] PHNO, and a Selective D3 Receptor Antagonist G Searle, JD Beaver, RA Comley, M Bani, A Tziortzi, M Slifstein, ... Biological Psychiatry 68 (4), 392-399, 2010 | 166 | 2010 |
Synaptic changes in Parkinson disease assessed with in vivo imaging D Matuskey, S Tinaz, KC Wilcox, M Naganawa, T Toyonaga, M Dias, ... Annals of neurology 87 (3), 329-338, 2020 | 136 | 2020 |
Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo L Marner, N Gillings, RA Comley, WFC Baaré, EA Rabiner, AA Wilson, ... Journal of Nuclear Medicine 50 (6), 900-908, 2009 | 105 | 2009 |
Radioligand development for molecular imaging of the central nervous system with positron emission tomography. M Honer, L Gobbi, L Martarello, R Comley Drug Discovery Today, 2014 | 84 | 2014 |
Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET S Ashworth, EA Rabiner, RN Gunn, C Plisson, AA Wilson, RA Comley, ... Journal of Nuclear Medicine 51 (7), 1021-1029, 2010 | 84 | 2010 |
Characterization of 3 novel tau radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in healthy controls and in Alzheimer subjects DF Wong, RA Comley, H Kuwabara, PB Rosenberg, SM Resnick, ... Journal of Nuclear Medicine 59 (12), 1869-1876, 2018 | 76 | 2018 |
Evaluation of 18F-RO-948 PET for quantitative assessment of tau accumulation in the human brain H Kuwabara, RA Comley, E Borroni, M Honer, K Kitmiller, J Roberts, ... Journal of Nuclear Medicine 59 (12), 1877-1884, 2018 | 76 | 2018 |
Kinetic modeling of the tau PET tracer 18F-AV-1451 in human healthy volunteers and Alzheimer disease subjects O Barret, D Alagille, S Sanabria, RA Comley, RM Weimer, E Borroni, ... Journal of Nuclear Medicine 58 (7), 1124-1131, 2017 | 75 | 2017 |
Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor CA Parker, RN Gunn, EA Rabiner, M Slifstein, R Comley, C Salinas, ... Journal of Nuclear Medicine 53 (2), 295-303, 2012 | 57 | 2012 |
Characterization of 3 PET tracers for quantification of mitochondrial and synaptic function in healthy human brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J A Mansur, EA Rabiner, RA Comley, Y Lewis, LT Middleton, M Huiban, ... Journal of Nuclear Medicine 61 (1), 96-103, 2020 | 56 | 2020 |
Radiation dose estimates for carbon-11-labelled PET tracers J van der Aart, WA Hallett, EA Rabiner, J Passchier, RA Comley Nuclear medicine and biology 39 (2), 305-314, 2012 | 49 | 2012 |
A comparison of gray matter density in restless legs syndrome patients and matched controls using voxel‐based morphometry RA Comley, S Cervenka, SE Palhagen, G Panagiotidis, JC Matthews, ... Journal of Neuroimaging 22 (1), 28-32, 2012 | 49 | 2012 |
A quantitative study of adipokinetic hormone of the firebug, Pyrrhocoris apterus GJ Goldsworthy, D Kodrik, R Comley, M Lightfoot Journal of insect physiology 48 (12), 1103-1109, 2002 | 47 | 2002 |
Mathematical Modelling of [11C]-(+)-PHNO Human Competition Studies GE Searle, JD Beaver, A Tziortzi, RA Comley, M Bani, G Ghibellini, ... NeuroImage, 2012 | 41 | 2012 |
The application of positron emission tomography (PET) imaging in CNS drug development I Suridjan, RA Comley, EA Rabiner Brain imaging and behavior 13, 354-365, 2019 | 37 | 2019 |
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease AV Venkataraman, A Mansur, G Rizzo, C Bishop, Y Lewis, E Kocagoncu, ... Science Translational Medicine 14 (658), eabk1051, 2022 | 35 | 2022 |
First in-human PET study of 3 novel tau radiopharmaceuticals:[11C] RO6924963,[11C] RO6931643, and [18F] RO6958948 DF Wong, R Comley, H Kuwabara, PB Rosenberg, SM Resnick, ... Journal of Nuclear Medicine, 2018 | 35 | 2018 |