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Sven Blokland
Sven Blokland
Scientist at Janssen Vaccines and Prevention
在 its.jnj.com 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
NS Laursen, RHE Friesen, X Zhu, M Jongeneelen, S Blokland, J Vermond, ...
Science 362 (6414), 598-602, 2018
2242018
Stabilizing the closed SARS-CoV-2 spike trimer
J Juraszek, L Rutten, S Blokland, P Bouchier, R Voorzaat, T Ritschel, ...
Nature communications 12 (1), 244, 2021
1492021
A small-molecule fusion inhibitor of influenza virus is orally active in mice
MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ...
Science 363 (6431), eaar6221, 2019
1202019
A universal approach to optimize the folding and stability of prefusion-closed HIV-1 envelope trimers
L Rutten, YT Lai, S Blokland, D Truan, IJM Bisschop, NM Strokappe, ...
Cell reports 23 (2), 584-595, 2018
912018
Structure-based design of prefusion-stabilized filovirus glycoprotein trimers
L Rutten, MSA Gilman, S Blokland, J Juraszek, JS McLellan, ...
Cell reports 30 (13), 4540-4550. e3, 2020
592020
Automated design by structure-based stabilization and consensus repair to achieve prefusion-closed envelope trimers in a wide variety of HIV strains
R Rawi, L Rutten, YT Lai, AS Olia, S Blokland, J Juraszek, CH Shen, ...
Cell reports 33 (8), 2020
382020
A universal approach to optimize the folding and stability of prefusion-closed HIV-1 envelope trimers. Cell Rep 23: 584–595
L Rutten, YT Lai, S Blokland, D Truan, IJM Bisschop, NM Strokappe, ...
102018
Automated design by structure-based stabilization and consensus repair to achieve prefusion-closed envelope trimers in a wide variety of HIV strains. Cell Rep 33: 108432
R Rawi, L Rutten, YT Lai, AS Olia, S Blokland, J Juraszek, CH Shen, ...
82020
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
X Yu, J Juraszek, L Rutten, MJG Bakkers, S Blokland, JM Melchers, ...
PLoS Pathogens 19 (5), e1011308, 2023
62023
An orally active small molecule fusion inhibitor of influenza virus
MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ...
Science (New York, NY) 363 (6431), 2019
32019
Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity
L Rutten, M Swart, A Koornneef, P Bouchier, S Blokland, A Sadi, ...
Scientific Reports 14 (1), 5735, 2024
22024
CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits
A Koornneef, K Vanshylla, G Hardenberg, L Rutten, NM Strokappe, ...
Nature communications 15 (1), 3128, 2024
12024
Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen
M Swart, H Kuipers, F Milder, M Jongeneelen, T Ritschel, J Tolboom, ...
npj Vaccines 8 (1), 176, 2023
12023
Antigen-binding protein directed against epitope in the CH1 domain of human IgG antibodies
WJJ Hermans, S Blokland, MAV Kesteren, JM Horrevoets, FJM Detmers
Google Patents, 2017
12017
CaptureSelect affinity ligands for antibody detection and characterization
P Hermans, G Grit, S Blokland, BAC BV
12013
Stabilized Filovirus glycoprotein trimers
J Langedijk, L Rutten, S Blokland
US Patent 11,603,390, 2023
2023
Stabilized filovirus glycoprotein trimers
JPM Langedijk, L RUTTEN, S BLOKLAND
2020
Antigen-Binding Protein Directed Against Epitope in the CH1 Domain of Human IgG Antibodies
WJJ Hermans, S Blokland, MA Van Kesteren, JM Horrevoets, ...
US Patent App. 15/799,920, 2018
2018
Sequential Immunization With Different Repaired and Stabilized HIV-1 Envelope Trimers Induces Broad Tier2 Neutralization in Rabbits
L Rutten, YT Lai, S Blokland, F Wegmann, G Hardenberg, D Truan, ...
AIDS RESEARCH AND HUMAN RETROVIRUSES 34, 337-337, 2018
2018
Antigen-binding protein directed against epitope in the CH1 domain of human IgG antibodies
WJJ Hermans, S Blokland, MA Van Kesteren, JM Horrevoets, ...
US Patent 9,850,315, 2017
2017
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