Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin NS Laursen, RHE Friesen, X Zhu, M Jongeneelen, S Blokland, J Vermond, ... Science 362 (6414), 598-602, 2018 | 224 | 2018 |
Stabilizing the closed SARS-CoV-2 spike trimer J Juraszek, L Rutten, S Blokland, P Bouchier, R Voorzaat, T Ritschel, ... Nature communications 12 (1), 244, 2021 | 149 | 2021 |
A small-molecule fusion inhibitor of influenza virus is orally active in mice MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ... Science 363 (6431), eaar6221, 2019 | 120 | 2019 |
A universal approach to optimize the folding and stability of prefusion-closed HIV-1 envelope trimers L Rutten, YT Lai, S Blokland, D Truan, IJM Bisschop, NM Strokappe, ... Cell reports 23 (2), 584-595, 2018 | 91 | 2018 |
Structure-based design of prefusion-stabilized filovirus glycoprotein trimers L Rutten, MSA Gilman, S Blokland, J Juraszek, JS McLellan, ... Cell reports 30 (13), 4540-4550. e3, 2020 | 59 | 2020 |
Automated design by structure-based stabilization and consensus repair to achieve prefusion-closed envelope trimers in a wide variety of HIV strains R Rawi, L Rutten, YT Lai, AS Olia, S Blokland, J Juraszek, CH Shen, ... Cell reports 33 (8), 2020 | 38 | 2020 |
A universal approach to optimize the folding and stability of prefusion-closed HIV-1 envelope trimers. Cell Rep 23: 584–595 L Rutten, YT Lai, S Blokland, D Truan, IJM Bisschop, NM Strokappe, ... | 10 | 2018 |
Automated design by structure-based stabilization and consensus repair to achieve prefusion-closed envelope trimers in a wide variety of HIV strains. Cell Rep 33: 108432 R Rawi, L Rutten, YT Lai, AS Olia, S Blokland, J Juraszek, CH Shen, ... | 8 | 2020 |
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike X Yu, J Juraszek, L Rutten, MJG Bakkers, S Blokland, JM Melchers, ... PLoS Pathogens 19 (5), e1011308, 2023 | 6 | 2023 |
An orally active small molecule fusion inhibitor of influenza virus MJP van Dongen, RU Kadam, J Juraszek, E Lawson, B Brandenburg, ... Science (New York, NY) 363 (6431), 2019 | 3 | 2019 |
Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity L Rutten, M Swart, A Koornneef, P Bouchier, S Blokland, A Sadi, ... Scientific Reports 14 (1), 5735, 2024 | 2 | 2024 |
CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits A Koornneef, K Vanshylla, G Hardenberg, L Rutten, NM Strokappe, ... Nature communications 15 (1), 3128, 2024 | 1 | 2024 |
Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen M Swart, H Kuipers, F Milder, M Jongeneelen, T Ritschel, J Tolboom, ... npj Vaccines 8 (1), 176, 2023 | 1 | 2023 |
Antigen-binding protein directed against epitope in the CH1 domain of human IgG antibodies WJJ Hermans, S Blokland, MAV Kesteren, JM Horrevoets, FJM Detmers Google Patents, 2017 | 1 | 2017 |
CaptureSelect affinity ligands for antibody detection and characterization P Hermans, G Grit, S Blokland, BAC BV | 1 | 2013 |
Stabilized Filovirus glycoprotein trimers J Langedijk, L Rutten, S Blokland US Patent 11,603,390, 2023 | | 2023 |
Stabilized filovirus glycoprotein trimers JPM Langedijk, L RUTTEN, S BLOKLAND | | 2020 |
Antigen-Binding Protein Directed Against Epitope in the CH1 Domain of Human IgG Antibodies WJJ Hermans, S Blokland, MA Van Kesteren, JM Horrevoets, ... US Patent App. 15/799,920, 2018 | | 2018 |
Sequential Immunization With Different Repaired and Stabilized HIV-1 Envelope Trimers Induces Broad Tier2 Neutralization in Rabbits L Rutten, YT Lai, S Blokland, F Wegmann, G Hardenberg, D Truan, ... AIDS RESEARCH AND HUMAN RETROVIRUSES 34, 337-337, 2018 | | 2018 |
Antigen-binding protein directed against epitope in the CH1 domain of human IgG antibodies WJJ Hermans, S Blokland, MA Van Kesteren, JM Horrevoets, ... US Patent 9,850,315, 2017 | | 2017 |