The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer AM Krebs, J Mitschke, M Lasierra Losada, O Schmalhofer, M Boerries, ... Nature cell biology 19 (5), 518-529, 2017 | 902 | 2017 |
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ... Nature medicine 24 (3), 282-291, 2018 | 264 | 2018 |
Cardiac adenoviral S100A1 gene delivery rescues failing myocardium P Most, ST Pleger, M Völkers, B Heidt, M Boerries, D Weichenhan, ... The Journal of clinical investigation 114 (11), 1550-1563, 2004 | 248 | 2004 |
Spatially confined sub-tumor microenvironments in pancreatic cancer BT Grünwald, A Devisme, G Andrieux, F Vyas, K Aliar, CW McCloskey, ... Cell 184 (22), 5577-5592. e18, 2021 | 233 | 2021 |
Spatially resolved multi-omics deciphers bidirectional tumor-host interdependence in glioblastoma VM Ravi, P Will, J Kueckelhaus, N Sun, K Joseph, H Salié, L Vollmer, ... Cancer cell 40 (6), 639-655. e13, 2022 | 212 | 2022 |
Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms A Prestipino, AJ Emhardt, K Aumann, D O’Sullivan, SP Gorantla, ... Science translational medicine 10 (429), eaam7729, 2018 | 210 | 2018 |
HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice R Hoefflin, S Harlander, S Schäfer, P Metzger, F Kuo, D Schönenberger, ... Nature communications 11 (1), 4111, 2020 | 185 | 2020 |
S100A1: A regulator of myocardial contractility PMJBPESTPMRMBFNBPPMLJTEPKGLSWJKHAKA Remppis PNAS 98 (24), 13889–13894, 2002 | 181* | 2002 |
Comprehensive genomic and transcriptomic analysis for guiding therapeutic decisions in patients with rare cancers P Horak, C Heining, S Kreutzfeldt, B Hutter, A Mock, J Hüllein, M Fröhlich, ... Cancer discovery 11 (11), 2780-2795, 2021 | 164 | 2021 |
MIRACUM: medical informatics in research and care in university medicine HU Prokosch, T Acker, J Bernarding, H Binder, M Boeker, M Boerries, ... Methods of information in medicine 57 (S 01), e82-e91, 2018 | 158 | 2018 |
From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract S Ebeling, K Naumann, S Pollok, T Wardecki, S Vidal-y-Sy, ... Plos one 9 (1), e86147, 2014 | 156 | 2014 |
T-cell dysfunction in the glioblastoma microenvironment is mediated by myeloid cells releasing interleukin-10 VM Ravi, N Neidert, P Will, K Joseph, JP Maier, J Kückelhaus, L Vollmer, ... Nature communications 13 (1), 925, 2022 | 149 | 2022 |
Conformation-specific antibodies reveal distinct actin structures in the nucleus and the cytoplasm CA Schoenenberger, S Buchmeier, M Boerries, R Sütterlin, U Aebi, ... Journal of structural biology 152 (3), 157-168, 2005 | 148 | 2005 |
Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks M Boerries, F Grahammer, S Eiselein, M Buck, C Meyer, M Goedel, ... Kidney international 83 (6), 1052-1064, 2013 | 147 | 2013 |
Combination of lenvatinib and pembrolizumab is an effective treatment option for anaplastic and poorly differentiated thyroid carcinoma C Dierks, J Seufert, K Aumann, J Ruf, C Klein, S Kiefer, M Rassner, ... Thyroid 31 (7), 1076-1085, 2021 | 137 | 2021 |
Ca2+-Dependent Interaction of S100A1 with F1-ATPase Leads to an Increased ATP Content in Cardiomyocytes M Boerries, P Most, JR Gledhill, JE Walker, HA Katus, WJ Koch, U Aebi, ... Molecular and cellular biology 27 (12), 4365-4373, 2007 | 127 | 2007 |
Quantitative evaluation of chromosomal rearrangements in gene-edited human stem cells by CAST-Seq G Turchiano, G Andrieux, J Klermund, G Blattner, V Pennucci, M El Gaz, ... Cell Stem Cell 28 (6), 1136-1147. e5, 2021 | 124 | 2021 |
Molecular consequences of SARS-CoV-2 liver tropism N Wanner, G Andrieux, P Badia-i-Mompel, C Edler, S Pfefferle, ... Nature metabolism 4 (3), 310-319, 2022 | 123 | 2022 |
RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia DB Lipka, T Witte, R Toth, J Yang, M Wiesenfarth, P Nöllke, A Fischer, ... Nature communications 8 (1), 2126, 2017 | 114 | 2017 |
Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation S Hamarsheh, L Osswald, BS Saller, S Unger, D De Feo, JM Vinnakota, ... Nature communications 11 (1), 1659, 2020 | 110 | 2020 |