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dahabada lopes
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Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins
S Sinha, DHJ Lopes, Z Du, ES Pang, A Shanmugam, A Lomakin, ...
Journal of the American Chemical Society 133 (42), 16958-16969, 2011
3412011
Mechanism of islet amyloid polypeptide fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy
DHJ Lopes, A Meister, A Gohlke, A Hauser, A Blume, R Winter
Biophysical journal 93 (9), 3132-3141, 2007
2102007
A key role for lysine residues in amyloid β-protein folding, assembly, and toxicity
S Sinha, DHJ Lopes, G Bitan
ACS Chemical Neuroscience 3 (6), 473-481, 2012
1392012
Contribuições da perspectiva institucional para a análise das organizações: possibilidades teóricas, empíricas e de aplicação
CA Carvalho, MMF Vieira, D LOPES
Organizações, cultura e desenvolvimento local: a agenda de pesquisa do …, 2003
1312003
Towards an understanding of the temperature/pressure configurational and free-energy landscape of biomolecules
R Winter, D Lopes, S Grudzielanek, K Vogtt
Walter de Gruyter 32 (1), 41-97, 2007
1122007
Angiotensin-converting enzyme overexpression in myelomonocytes prevents Alzheimer’s-like cognitive decline
KE Bernstein, Y Koronyo, BC Salumbides, J Sheyn, L Pelissier, ...
The Journal of clinical investigation 124 (3), 1000-1012, 2014
1102014
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
M Koronyo-Hamaoui, J Sheyn, EY Hayden, S Li, DT Fuchs, GC Regis, ...
Brain 143 (1), 336-358, 2020
662020
Induction of methionine-sulfoxide reductases protects neurons from amyloid β-protein insults in vitro and in vivo
J Moskovitz, P Maiti, DHJ Lopes, DB Oien, A Attar, T Liu, S Mittal, J Hayes, ...
Biochemistry 50 (49), 10687-10697, 2011
662011
Design of β-amyloid aggregation inhibitors from a predicted structural motif
PA Novick, DH Lopes, KM Branson, A Esteras-Chopo, IA Graef, G Bitan, ...
Journal of Medicinal Chemistry 55 (7), 3002-3010, 2012
642012
Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism
DHJ Lopes, A Attar, G Nair, EY Hayden, Z Du, K McDaniel, S Dutt, ...
ACS chemical biology 10 (6), 1555-1569, 2015
532015
Amyloidogenicity and cytotoxicity of recombinant mature human islet amyloid polypeptide (rhIAPP)
DHJ Lopes, C Colin, TL Degaki, ACV de Sousa, MNN Vieira, A Sebollela, ...
Journal of Biological Chemistry 279 (41), 42803-42810, 2004
512004
C-terminal tetrapeptides inhibit Aβ42-induced neurotoxicity primarily through specific interaction at the N-terminus of Aβ42
H Li, Z Du, DHJ Lopes, EA Fradinger, C Wang, G Bitan
Journal of medicinal chemistry 54 (24), 8451-8460, 2011
392011
Urea increases tolerance of yeast inorganic pyrophosphatase activity to ethanol: the other side of urea interaction with proteins
DHJ Lopes, M Sola-Penna
Archives of Biochemistry and Biophysics 394 (1), 61-66, 2001
362001
Effects of trehalose and ethanol on yeast cytosolic pyrophosphatase
DHJ Lopes, JR Meyer-Fernandes, M Sola-Penna
Zeitschrift für Naturforschung C 54 (3-4), 186-190, 1999
201999
Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis
DHJ Lopes, A Chapeaurouge, GA Manderson, JS Johansson, ST Ferreira
Journal of Biological Chemistry 279 (12), 10991-10996, 2004
182004
Tranilast binds to Aβ monomers and promotes Aβ fibrillation
CR Connors, DJ Rosenman, DHJ Lopes, S Mittal, G Bitan, M Sorci, ...
Biochemistry 52 (23), 3995-4002, 2013
172013
Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins
DHJ Lopes, S Sinha, C Rosensweig, G Bitan
Amyloid Proteins: Methods and Protocols, 11-21, 2012
162012
A Two‐Step Strategy for Structure–Activity Relationship Studies of NMethylated Aβ42 C‐Terminal Fragments as Aβ42 Toxicity Inhibitors
H Li, R Zemel, DHJ Lopes, BH Monien, G Bitan
ChemMedChem 7 (3), 515-522, 2012
132012
Islet amyloid polypeptide and high hydrostatic pressure: towards an understanding of the fibrillization process
DHJ Lopes, V Smirnovas, R Winter
Journal of Physics: Conference Series 121 (11), 112002, 2008
32008
Mechanism of IAPP fibrillation at lipid interfaces studied by infrared reflection absorption spectroscopy
DHJ Lopes, A Meister, A Gohlke, A Hauser, A Blume, R Winter
Biophys J. doi 10, 2007
32007
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