Landscape of intercellular crosstalk in healthy and NASH liver revealed by single-cell secretome gene analysis X Xiong, H Kuang, S Ansari, T Liu, J Gong, S Wang, XY Zhao, Y Ji, C Li, ... Molecular cell 75 (3), 644-660. e5, 2019 | 576 | 2019 |
The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis GX Wang, XY Zhao, ZX Meng, M Kern, A Dietrich, Z Chen, Z Cozacov, ... Nature medicine 20 (12), 1436-1443, 2014 | 466 | 2014 |
Hepatic neuregulin 4 signaling defines an endocrine checkpoint for steatosis-to-NASH progression L Guo, P Zhang, Z Chen, H Xia, S Li, Y Zhang, S Kobberup, W Zou, JD Lin The Journal of clinical investigation 127 (12), 4449-4461, 2017 | 148 | 2017 |
Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders Z Chen, GX Wang, SL Ma, DY Jung, H Ha, T Altamimi, XY Zhao, L Guo, ... Molecular metabolism 6 (8), 863-872, 2017 | 121 | 2017 |
Cyclodepsipeptide toxin promotes the degradation of Hsp90 client proteins through chaperone-mediated autophagy S Shen, P Zhang, MA Lovchik, Y Li, L Tang, Z Chen, R Zeng, D Ma, ... Journal of Cell Biology 185 (4), 629-639, 2009 | 100 | 2009 |
Glucose sensing by skeletal myocytes couples nutrient signaling to systemic homeostasis ZX Meng, J Gong, Z Chen, J Sun, Y Xiao, L Wang, Y Li, J Liu, XZS Xu, ... Molecular cell 66 (3), 332-344. e4, 2017 | 61 | 2017 |
The obesity-induced adipokine sST2 exacerbates adipose Treg and ILC2 depletion and promotes insulin resistance XY Zhao, L Zhou, Z Chen, Y Ji, X Peng, L Qi, S Li, JD Lin Science advances 6 (20), eaay6191, 2020 | 56 | 2020 |
miR-92b regulates Mef2 levels through a negative-feedback circuit during Drosophila muscle development Z Chen, S Liang, Y Zhao, Z Han Development 139 (19), 3543-3552, 2012 | 54 | 2012 |
NRG1-Fc improves metabolic health via dual hepatic and central action P Zhang, H Kuang, Y He, SO Idiga, S Li, Z Chen, Z Yang, X Cai, K Zhang, ... JCI insight 3 (5), 2018 | 45 | 2018 |
Neuregulin 4 suppresses NASH-HCC development by restraining tumor-prone liver microenvironment P Zhang, Z Chen, H Kuang, T Liu, J Zhu, L Zhou, Q Wang, X Xiong, ... Cell metabolism 34 (9), 1359-1376. e7, 2022 | 43 | 2022 |
Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation Z Chen, X Sun, S Shen, H Zhang, X Ma, J Liu, S Kuang, Q Yu Journal of Biological Chemistry 288 (20), 14417-14427, 2013 | 42 | 2013 |
hnRNPU/TrkB defines a chromatin accessibility checkpoint for liver injury and nonalcoholic steatohepatitis pathogenesis J Xiong, T Liu, L Mi, H Kuang, X Xiong, Z Chen, S Li, JD Lin Hepatology 71 (4), 1228-1246, 2020 | 34 | 2020 |
Wnt4 is required for ostia development in the Drosophila heart Z Chen, J Zhu, Y Fu, A Richman, Z Han Developmental biology 413 (2), 188-198, 2016 | 12 | 2016 |
Negative regulation of interferon-γ/STAT1 signaling through cell adhesion and cell density-dependent STAT1 dephosphorylation Z Chen, X Ma, H Zhang, X Sun, S Shen, Y Li, Y Gu, Y Wang, S Yan, Q Yu Cellular signalling 23 (8), 1404-1412, 2011 | 10 | 2011 |
ROS signaling–induced mitochondrial Sgk1 expression regulates epithelial cell renewal Y Li, C Liu, L Rolling, V Sikora, Z Chen, J Gurwin, C Barabell, J Lin, ... Proceedings of the National Academy of Sciences 120 (24), e2216310120, 2023 | 5 | 2023 |
Intrahepatic paracrine signaling by cardiotrophin‐like cytokine factor 1 ameliorates diet‐induced NASH in mice T Liu, Q Wang, L Zhou, P Zhang, L Mi, X Qiu, Z Chen, H Kuang, S Li, ... Hepatology 78 (5), 1478-1491, 2023 | 4 | 2023 |
Myeloid-specific ablation of Basp1 ameliorates diet-induced NASH in mice by attenuating pro-inflammatory signaling Z Meng, L Zhou, S Hong, X Qiu, Z Chen, T Liu, K Inoki, JD Lin Hepatology 79 (2), 409-424, 2024 | 1 | 2024 |
Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo VT Tang, J Xiang, Z Chen, J McCormick, PS Abbineni, XW Chen, ... Proceedings of the National Academy of Sciences 121 (19), e2322164121, 2024 | | 2024 |
MiR-92b is a heart and muscle specific microRNA that regulates Mef2 level through a negative feedback loop in Drosophila. 2 Zhimin Chen1, Shanshan Liang1, Ying Zhao1, Zhe Han1 53rd Annual Drosophila Research Conference, 2012 | | 2012 |