Delivery and specificity of CRISPR/Cas9 genome editing technologies for human gene therapy JL Gori, PD Hsu, ML Maeder, S Shen, GG Welstead, D Bumcrot Human gene therapy 26 (7), 443-451, 2015 | 262 | 2015 |
Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells JL Gori, JM Butler, YY Chan, D Chandrasekaran, MG Poulos, M Ginsberg, ... The Journal of clinical investigation 125 (3), 1243-1254, 2015 | 131 | 2015 |
Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients JE Adair, SK Johnston, MM Mrugala, BC Beard, LA Guyman, AL Baldock, ... The Journal of clinical investigation 124 (9), 4082-4092, 2014 | 101 | 2014 |
Safeguarding nonhuman primate iPS cells with suicide genes B Zhong, KL Watts, JL Gori, ME Wohlfahrt, J Enssle, JE Adair, HP Kiem Molecular Therapy 19 (9), 1667-1675, 2011 | 62 | 2011 |
Hepatic cells derived from induced pluripotent stem cells of pigtail macaques support hepatitis C virus infection M Sourisseau, O Goldman, W He, JL Gori, HP Kiem, V Gouon–Evans, ... Gastroenterology 145 (5), 966-969. e7, 2013 | 55 | 2013 |
Efficient generation, purification, and expansion of CD34+ hematopoietic progenitor cells from nonhuman primate–induced pluripotent stem cells JL Gori, D Chandrasekaran, JP Kowalski, JE Adair, BC Beard, ... Blood, The Journal of the American Society of Hematology 120 (13), e35-e44, 2012 | 47 | 2012 |
Crispr/cas-mediated gene conversion C Cotta-Ramusino, JL Gori US Patent App. 15/081,456, 2016 | 40 | 2016 |
Endothelial cells promote expansion of long-term engrafting marrow hematopoietic stem and progenitor cells in primates JL Gori, JM Butler, B Kunar, MG Poulos, M Ginsberg, DJ Nolan, ... Stem cells translational medicine 6 (3), 864-876, 2017 | 36 | 2017 |
Counterselection and Co-Delivery of Transposon and Transposase Functions for Sleeping Beauty-Mediated Transposition in Cultured Mammalian Cells AD Converse, LR Belur, JL Gori, G Liu, F Amaya, E Aguilar-Cordova, ... Bioscience reports 24 (6), 577-594, 2004 | 34 | 2004 |
Protection of mice from methotrexate toxicity by ex vivo transduction using lentivirus vectors expressing drug-resistant dihydrofolate reductase JL Gori, K Podetz-Pedersen, D Swanson, AD Karlen, R Gunther, ... Journal of Pharmacology and Experimental Therapeutics 322 (3), 989-997, 2007 | 24 | 2007 |
Optimized CRISPR/cas9 systems and methods for gene editing in stem cells JL Gori US Patent 11,390,884, 2022 | 22 | 2022 |
Crispr/cas-related methods, compositions and components GG Welstead, JL Gori, JM Heath, DA Bumcrot US Patent App. 15/560,968, 2018 | 20 | 2018 |
In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model JL Gori, BC Beard, C Ironside, G Karponi, HP Kiem Cancer gene therapy 19 (8), 523-529, 2012 | 19 | 2012 |
CRISPR/Cas-related methods and compositions for improving transplantation JL Gori, T Wang, H Jayaram, P Odonnell US Patent 11,911,415, 2024 | 12 | 2024 |
In vivo selection of human embryonic stem cell-derived cells expressing methotrexate-resistant dihydrofolate reductase JL Gori, X Tian, D Swanson, R Gunther, LD Shultz, RS McIvor, ... Gene therapy 17 (2), 238-249, 2010 | 11 | 2010 |
Crispr/cas-related methods and compositions for treating hiv infection and aids JL Gori, GG Welstead, P Odonnell US Patent App. 15/809,549, 2018 | 7 | 2018 |
Prime Editing Efficiently and Precisely Corrects Causative Mutation in Chronic Granulomatous Disease, Restoring Myeloid Function: Toward Development of a Prime Edited … JM Heath, JS Orenstein, JG Tedeschi, A Ng, MD Collier, J Kushakji, ... Blood 142, 7129, 2023 | 6 | 2023 |
Cpf1-related methods and compositions for gene editing J Gori, J Zuris, H Jayaram US Patent App. 16/899,302, 2020 | 6 | 2020 |
Multiplex Prime Editing and PASSIGE TM for Non-Viral Generation of an Allogeneic CAR-T Cell Product EJ Pomeroy, AV Anzalone, CJ Podracky, NB Bloch, R Chang, AA Dwivedi, ... Blood 142, 4803, 2023 | 4 | 2023 |
In vivo protection of activated Tyr22‐dihydrofolate reductase gene‐modified canine T lymphocytes from methotrexate JL Gori, BC Beard, NP Williams, C Ironside, D Swanson, R Scott McIvor, ... The journal of gene medicine 15 (6-7), 233-241, 2013 | 4 | 2013 |