Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases K Das Gupta, MR Shakespear, A Iyer, DP Fairlie, MJ Sweet Clinical & translational immunology 5 (1), e62, 2016 | 113 | 2016 |
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells X Sun, B Cao, M Naval-Sanchez, T Pham, YBY Sun, B Williams, ... Nature communications 12 (1), 2665, 2021 | 62 | 2021 |
Class IIa histone deacetylases drive toll-like receptor-inducible glycolysis and macrophage inflammatory responses via pyruvate kinase M2 KD Gupta, MR Shakespear, JEB Curson, AMV Murthy, A Iyer, MP Hodson, ... Cell reports 30 (8), 2712-2728. e8, 2020 | 58 | 2020 |
Histone deacetylase inhibitors promote mitochondrial reactive oxygen species production and bacterial clearance by human macrophages JK Ariffin, K das Gupta, R Kapetanovic, A Iyer, RC Reid, DP Fairlie, ... Antimicrobial agents and chemotherapy 60 (3), 1521-1529, 2016 | 58 | 2016 |
Lysine deacetylases and regulated glycolysis in macrophages MR Shakespear, A Iyer, CY Cheng, KD Gupta, A Singhal, DP Fairlie, ... Trends in immunology 39 (6), 473-488, 2018 | 56 | 2018 |
Histone deacetylase 7: a signalling hub controlling development, inflammation, metabolism and disease Y Wang, R Abrol, JYW Mak, K Das Gupta, D Ramnath, D Karunakaran, ... The FEBS journal 290 (11), 2805-2832, 2023 | 24 | 2023 |
SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages RM Lucas, L Liu, JEB Curson, YWH Koh, N Tuladhar, ND Condon, ... Cell Reports 36 (10), 2021 | 13 | 2021 |
The histone deacetylase Hdac7 supports LPS-inducible glycolysis and Il-1β production in murine macrophages via distinct mechanisms D Ramnath, K Das Gupta, Y Wang, R Abrol, JEB Curson, J Lim, RC Reid, ... Journal of Leukocyte Biology 111 (2), 327-336, 2022 | 11 | 2022 |
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages K Das Gupta, D Ramnath, JB von Pein, JEB Curson, Y Wang, R Abrol, ... Proceedings of the National Academy of Sciences 120 (4), e2212813120, 2023 | 3 | 2023 |
CFTR is required for zinc-mediated antibacterial defense in human macrophages K Das Gupta, JEB Curson, AA Tarique, R Kapetanovic, MA Schembri, ... Proceedings of the National Academy of Sciences 121 (8), e2315190121, 2024 | 1 | 2024 |
The Brass Dagger: How macrophages deploy Zinc and Copper as an antibacterial weapon? R Kapetanovic, C Stocks, K das Gupta, J von Pein, MJ Sweet FrenchBic annual meeting/French-Japanese Symposium on BioInorganic chemistry, 2024 | | 2024 |
Suggested searches JA Smith, BTK Yuen, W Purtha, JM Balolong, JD Phipps, F Crawford, ... Perspective, 2024 | | 2024 |
Histone deacetylase 7 (HDAC7) regulates a sub-set of TLR-mediated pro-inflammatory responses in macrophages by both deacetylase-dependent and-independent mechanisms K Das Gupta, M Shakespear, K Tunny, D Hohenhaus, JN Bokil, A Iyer, ... European Journal of Immunology 46, 833-834, 2016 | | 2016 |