Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis Y Touil, W Igoudjil, M Corvaisier, AF Dessein, J Vandomme, D Monté, ... Clinical cancer research 20 (4), 837-846, 2014 | 324 | 2014 |
Inactivation of the HIF-1α/PDK3 signaling axis drives melanoma toward mitochondrial oxidative metabolism and potentiates the therapeutic activity of pro-oxidants J Kluza, P Corazao-Rozas, Y Touil, M Jendoubi, C Maire, P Guerreschi, ... Cancer research 72 (19), 5035-5047, 2012 | 175 | 2012 |
Liposomal encapsulation of the natural flavonoid fisetin improves bioavailability and antitumor efficacy J Seguin, L Brullé, R Boyer, YM Lu, MR Romano, YS Touil, D Scherman, ... International journal of pharmaceutics 444 (1-2), 146-154, 2013 | 141 | 2013 |
Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice YS Touil, J Seguin, D Scherman, GG Chabot Cancer chemotherapy and pharmacology 68, 445-455, 2011 | 114 | 2011 |
Development of a liposomal formulation of the natural flavonoid fisetin N Mignet, J Seguin, MR Romano, L Brullé, YS Touil, D Scherman, ... International journal of pharmaceutics 423 (1), 69-76, 2012 | 109 | 2012 |
Fisetin disposition and metabolism in mice: Identification of geraldol as an active metabolite YS Touil, N Auzeil, F Boulinguez, H Saighi, A Regazzetti, D Scherman, ... Biochemical pharmacology 82 (11), 1731-1739, 2011 | 101 | 2011 |
Flavonoid-induced morphological modifications of endothelial cells through microtubule stabilization YS Touil, A Fellous, D Scherman, GG Chabot Nutrition and cancer 61 (3), 310-321, 2009 | 90 | 2009 |
The PI3K/AKT signaling pathway controls the quiescence of the low-Rhodamine123-retention cell compartment enriched for melanoma stem cell activity Y Touil, T Zuliani, I Wolowczuk, K Kuranda, J Prochazkova, J Andrieux, ... Stem cells 31 (4), 641-651, 2013 | 72 | 2013 |
Nerve growth factor and proNGF simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell … E Tomellini, Y Touil, C Lagadec, S Julien, P Ostyn, N Ziental-Gelus, ... Stem Cells 33 (2), 342-353, 2015 | 65 | 2015 |
TRPC3 shapes the ER-mitochondria Ca2+ transfer characterizing tumour-promoting senescence V Farfariello, DV Gordienko, L Mesilmany, Y Touil, E Germain, I Fliniaux, ... Nature communications 13 (1), 956, 2022 | 42 | 2022 |
Insulin-like growth factor 1 receptor and p38 mitogen-activated protein kinase signals inversely regulate signal transducer and activator of transcription 3 activity to control … J Vandomme, Y Touil, P Ostyn, C Olejnik, P Flamenco, R El Machhour, ... Stem Cells and Development 23 (8), 839-851, 2014 | 36 | 2014 |
Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells Y Touil, P Segard, P Ostyn, S Begard, C Aspord, R El Machhour, ... Scientific Reports 6 (1), 30405, 2016 | 33 | 2016 |
Transient TNF regulates the self-renewing capacity of stem-like label-retaining cells in sphere and skin equivalent models of melanoma P Ostyn, R El Machhour, S Begard, N Kotecki, J Vandomme, P Flamenco, ... Cell Communication and Signaling 12, 1-13, 2014 | 27 | 2014 |
Flavonoids in cancer prevention and therapy: chemistry, pharmacology, mechanisms of action, and perspectives for cancer drug discovery GG Chabot, YS Touil, MH Pham, D Dauzonne Alternative and Complementary Therapies for Cancer: Integrative Approaches …, 2010 | 25 | 2010 |
Aggressiveness potential of spontaneous canine mucosal melanoma can dictate distinct cancer stem cell compartment behaviors in regard to their initial size and expansion abilities Y Touil, Z Segaoula, X Thuru, S Galiegue-Zouitina, D Tierny, B Quesnel Stem Cells and Development 29 (14), 919-928, 2020 | 7 | 2020 |
Pairing cells of different sizes in a microfluidic device for immunological synapse monitoring FA Shaik, C Lewuillon, A Guillemette, B Ahmadian, C Brinster, B Quesnel, ... Lab on a Chip 22 (5), 908-920, 2022 | 6 | 2022 |
Involvement of ORAI1/SOCE in human AML cell lines and primary cells according to ABCB1 activity, LSC compartment and potential resistance to ara-C exposure C Lewuillon, A Guillemette, S Titah, FA Shaik, N Jouy, O Labiad, ... International Journal of Molecular Sciences 23 (10), 5555, 2022 | 5 | 2022 |
p65/RelA NF‐κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics Y Touil, C Latreche‐Carton, HE Bouazzati, AL Nugues, N Jouy, X Thuru, ... Journal of Cellular Biochemistry 123 (3), 543-556, 2022 | 4 | 2022 |
Put in a “Ca2+ll” to Acute Myeloid Leukemia C Lewuillon, MO Laguillaumie, B Quesnel, T Idziorek, Y Touil, ... Cells 11 (3), 543, 2022 | 4 | 2022 |
Synergistic antiangiogenic and antitumoral effects of the combination of the flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma bearing mice Y Touil, J Seguin, D Scherman, G Chabot CANCER RESEARCH 69, 2009 | 2 | 2009 |